Výsledky vyhledávání - "Gareth R. Lewis"

Akademický článek

SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans.

Autor: Clare F Price, David Tyssen, Secondo Sonza, Ashley Davie, Sonya Evans, Gareth R Lewis, Shirley Xia, Tim Spelman, Peter Hodsman, Thomas R Moench, Andrew Humberstone, Jeremy R A Paull, Gilda Tachedjian

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24095 (2011)

UnlabelledSPL7013 Gel (VivaGel(®)) is a microbicide in development for prevention of HIV and HSV. This clinical study assessed retention and duration of antiviral activity following vaginal administration of 3% SPL7013 Gel in healthy women. Particip

Externí odkaz: https://doaj.org/article/bdfe8b68946e44cf931a6d338a6ecc77

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Akademický článek

Structure activity relationship of dendrimer microbicides with dual action antiviral activity.

Autor: David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R Gorry, Paul A Ramsland, Richard Cone, Jeremy R A Paull, Gareth R Lewis, Gilda Tachedjian

Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12309 (2010)

Topical microbicides, used by women to prevent the transmission of HIV and other sexually transmitted infections are urgently required. Dendrimers are highly branched nanoparticles being developed as microbicides. However, the anti-HIV and HSV struct

Externí odkaz: https://doaj.org/article/8e209eef94d84445b4f108cdfa4f797f

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Hydrophobic vs. Hydrophilic: Ionic Competition in Remacemide Salt Structures

Autor: Gareth R. Lewis, Gerry Steele, Lorraine McBride, Alastair J. Florence, Alan R. Kennedy, Norman Shankland, William I. F. David, Kenneth Shankland, Simon J. Teat

Publikováno v: Crystal Growth & Design. 5:427-438

Remacemide [2-amino-N-(1-methyl-1,2-diphenylethyl)-acetamide] was developed as a potential antagonist for epilepsy, Parkinsonism, and Huntington's disease. This paper investigates hydrophilic and hydrophobic intermolecular interactions that occur wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92f055155f24007b40fc45752ce41d2c
https://doi.org/10.1021/cg049836u

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A prospective study of the predictive power of spiral computed tomographic angiography for defining renal vascular anatomy before live-donor nephrectomy

Autor: Nicolas R. Brook, Michael L. Nicholson, Peter S. Veitch, Kevin Mulcahy, Gareth R. Lewis

Publikováno v: BJU International. 94:1077-1081

The advent of laparoscopic donor nephrectomy for renal transplantation has focused minds to an even greater degree on the vascular anatomy of the donor kidney. The authors from Leicester determined the accuracy of spiral CT imaging for donor venous a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ed7ea5dbd9441855374e5dc14b9da2
https://doi.org/10.1111/j.1464-410x.2004.05107.x

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Cyanide-bridged complexes with Sn(II)Mn(I), Sn(II)Mn(II), Sn(IV)Mn(I) and Sn(IV)Mn(II) oxidation states †

Autor: Kirsty M. Anderson, Neil G. Connelly, Maria Teresa Moreno, A. Guy Orpen, Andrew J. Wood, Nicholas J. Goodwin, Gareth R. Lewis

Publikováno v: RIUR: Repositorio Institucional de la Universidad de La Rioja
Universidad de La Rioja (UR)
Scopus-Elsevier
RIUR. Repositorio Institucional de la Universidad de La Rioja
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The redox-active cyanomanganese carbonyl ligands trans- and cis-[Mn(CN)(CO)2(PR3)(dppm)] (R = OEt or OPh, dppm = Ph2PCH2PPh2) and trans-[Mn(CN)(CO)(dppm)2] react with SnCl2 to give [Cl2SnII(μ-NC)MnILx] [Lx = trans- and cis-(CO)2(PR3)(dppm), R = OEt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e200384d1380f7981ec898e5d230972
https://doi.org/10.1039/b100721l

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Crystal supramolecularity: multiple phenyl embraces formed by [AsPh4]+ cations

Autor: Gareth R. Lewis, Ian G. Dance

Publikováno v: Inorganica Chimica Acta. 306:160-167

Analysis of the 483 crystals in the Cambridge Structural Database containing [AsPh4]+ cations has revealed mutually attractive interactions between the cations leading to the formation of supramolecular motifs. The types of inter-cation interaction c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66d6c0e39e8f0c500f72e409e7f4228a
https://doi.org/10.1016/s0020-1693(00)00164-x

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Supramolecular potentials and embraces for fluorous aromatic molecules

Autor: Susan Lorenzo, Gareth R. Lewis, Ian G. Dance

Publikováno v: New Journal of Chemistry. 24:295-304

In order to understand better the supramolecular chemistry of fluorous molecules, and particularly coordination complexes and organometallic molecules with perfluoroaromatic substituents, the relevant intermolecular potentials have been parametrised.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ea60aeb3b9168b362ef4b274aeaa53
https://doi.org/10.1039/a909540c

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Crystal supramolecular motifs for [Ph4P]+ salts of [M(mnt)2]2−, [M(mnt)2]−, [{M(mnt)2}2]2−, [M(mnt)3]3− and [M(mnt)3]2− (mnt2− = maleonitriledithiolate) †

Autor: Ian G. Dance, Gareth R. Lewis

Publikováno v: Journal of the Chemical Society, Dalton Transactions. :3176-3185

The crystal structures of [Ph4P]2[M(mnt)2] (M = Zn 1, Cu 2 or Ni 3), [Ph4P][M(mnt)2] (M = Cu 4 or Ni 5), [Ph4P]2[{M(mnt)2}2] (M = Co 6 or Fe 7), [Ph4P]2[M(mnt)3] (M = Fe 8 or Cr 10) and [Ph4P]3[Cr(mnt)3] 9 {mnt = maleonitriledithiolate, [S2C2(CN)2]2�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fff4ac3502add96987db4f356b01fec
https://doi.org/10.1039/b000093k

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Structure dependence on redox state and charge in [Fe4(μ3-S4)(η-C5H5)4]m[M(mnt)2]n (M = Ni or Pt, m, n = 1 or 2)

Autor: Gareth R. Lewis, Peter Thornton, Dena Bellamy, A. Guy Orpen, Neil G. Connelly, Aristides Christofides

Publikováno v: Journal of the Chemical Society, Dalton Transactions. :4038-4043

The complex salts [Fe4(μ3-S)4(η-C5H5)4]m[M(mnt)2]n {M = Ni, n = 2, m = 1 1; n = 1, m = 1 2 or 2 3: M = Pt, n = 2, m = 1 4; n = 1, m = 1 5 or 2 6; mnt = S2C2(CN)2} have been synthesized by stoichiometric reactions between [NEt4]n[M(mnt)2] (n = 1 or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32e41a6f97a60400d4e5c3c4bcef2abd
https://doi.org/10.1039/b006262f

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Organic–inorganic hybrid solids: control of perhalometallate solid state structures †

Autor: Amy L. Gillon, Xi-Meng Wang, Yolanda Rodríguez-Martín, Sarah Rotter, A. Guy Orpen, Gareth R. Lewis, Catalina Ruiz-Pérez, Jonathan Starbuck

Publikováno v: Journal of the Chemical Society, Dalton Transactions. :3897-3905

MX⋯HN+ hydrogen bond synthons have been exploited in preparation of crystalline salts [4,4′-H2bipy][MX4] [X = Cl, M = Pd, Pt, Co, Zn, Hg, Mn, Cd and Pb; X = Br, M = Pd, Co, Zn and Mn]. In these salts three structural forms for the halometallate s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce7519da2e836696af768994bbe66e05
https://doi.org/10.1039/b005036i

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