Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Gareth J Sanger"'
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269689 (2022)
BackgroundThe effect of ageing on total collagen content of human colon has been poorly investigated. The aim of this study was to determine if ageing altered total collagen content and distribution in the human colon.MethodsMacroscopically normal as
Externí odkaz:
https://doaj.org/article/2330909000ed4b42837bef258499dc67
Autor:
Nicholas Baidoo, Gareth J. Sanger
Publikováno v:
Experimental and Molecular Pathology, Vol 139, Iss , Pp 104923- (2024)
Background & aims: Older people experience a greater incidence of lower bowel disorders, including constipation. Causes can include factors associated with growing older, such as use of medications or disease, but compounded by degenerative changes w
Externí odkaz:
https://doaj.org/article/77c983507d7e48f49989a33a3b1f5f09
Publikováno v:
Frontiers in Pharmacology, Vol 1 (2011)
During hunger, a series of high-amplitude contractions of the stomach and small intestine (phase III), which form part of a cycle of quiescence and contractions (known as the migrating motor complex; MMC), play a ‘housekeeping’ role prior to the
Externí odkaz:
https://doaj.org/article/dc680dbb6ba2409b8e90fa538bb9b6d2
Publikováno v:
MethodsX, Vol 11, Iss , Pp 102416- (2023)
Collagen is the most abundant structural protein and extracellular matrix component in mammals. In the colon, collagen fibres reside in all the major sublayers; namely, the mucosa, submucosa, muscularis externa and the serosa. Methods to quantify col
Externí odkaz:
https://doaj.org/article/18ec1d50c7a446479f4ea1ede2f29516
Autor:
Marilisa Straface, Marie-Ange Kouassi, Raj Makwana, Ellie Crawley, Alexandra Palmer, Weigang Cai, Armen Gharibans, Miriam Adebibe, John Loy, Greg O’Grady, Paul LR Andrews, Gareth J. Sanger
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106247- (2022)
Electrical slow waves, generated by interstitial cells of Cajal (ICC), cause spontaneous contractions of human stomach. Software was developed to measure muscle tone and eleven different parameters defining these contractions in human stomach, displa
Externí odkaz:
https://doaj.org/article/6545b2f4a9034b76bc76a3087d12427a
Autor:
Gareth J. Sanger
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract The gastrointestinal (GI) hormone motilin helps control human stomach movements during hunger and promotes hunger. Although widely present among mammals, it is generally accepted that in rodents the genes for motilin and/or its receptor have
Externí odkaz:
https://doaj.org/article/dc819d461e544936933a215f97be4bca
Autor:
Gareth J. Sanger, Paul L. R. Andrews
Publikováno v:
Alimentary Pharmacology & Therapeutics. 57:962-978
Autor:
Raj Makwana, Ellie Crawley, Marilisa Straface, Alexandra Palmer, Armen Gharibans, Kalpana Devalia, John Loy, Greg O'Grady, Paul L. R. Andrews, Gareth J. Sanger
Publikováno v:
British Journal of Pharmacology. 179:5305-5322
BACKGROUND AND PURPOSE: Nausea is associated with the hormonal secretion of vasopressin and adrenaline, although their actions in inducing nausea is poorly understood. Here, we have investigated their actions on human stomach muscle. EXPERIMENTAL APP
Autor:
Gareth J. Sanger, Paul L.R. Andrews
Publikováno v:
Gastroenterology.