Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gareth D, Griffiths"'
Autor:
Gareth D. Griffiths
Publikováno v:
Toxins, Vol 3, Iss 11, Pp 1373-1392 (2011)
The toxin ricin has long been understood to have potential for criminal activity and there has been concern that it might be used as a mass-scale weapon on a military basis for at least two decades. Currently, the focus has extended to encompass terr
Externí odkaz:
https://doaj.org/article/da0e3d75bb8240d99a31fe6232ea6adf
Autor:
Sarah J. C. Whitfield, Gareth D. Griffiths, Dominic C. Jenner, Robert J. Gwyther, Fiona M. Stahl, Lucy J. Cork, Jane L. Holley, A. Christopher Green, Graeme C. Clark
Publikováno v:
Toxins, Vol 9, Iss 10, p 329 (2017)
Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and inci
Externí odkaz:
https://doaj.org/article/96cfe0f83b8141faa9b71d3620e7e162
Autor:
Gareth D. Griffiths, Ethel Diane Williamson, Jane E. Risdall, Alun Carter, Sarah Joanne Christine Whitfield
Publikováno v:
Advances in Bioscience and Biotechnology. :1-12
Staphylococcal Enterotoxin B (SEB) is considered a potential biological weapon. It is toxic by both inhalation and ingestion. Effects of ingestion include fever, vomiting and diarrhoea, while inhalation may additionally result in chest pain, dyspnoea
Autor:
A. Christopher Green, Gareth D. Griffiths, Sarah J C Whitfield, Graeme C. Clark, Lucy Jane Cork, Fiona M. Stahl, Jane L Holley, Robert J Gwyther, Dominic C. Jenner
Publikováno v:
Toxins, Vol 9, Iss 10, p 329 (2017)
Toxins; Volume 9; Issue 10; Pages: 329
Toxins
Toxins; Volume 9; Issue 10; Pages: 329
Toxins
Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and inci
Autor:
Sarah Joanne Christine Whitfield, Christopher Taylor, Gareth D. Griffiths, Sandrine Vessillier, A. Christopher Green, Sjoerd Rijpkema, Luisa Saraiva, Jane E. Risdall, E. Diane Williamson, Alun Carter, James T. A. Jones
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(10)
Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo. Exposure to the toxin can be lethal and cause signi
Publikováno v:
Microbes and Infection. 14:369-379
Interactions between Francisella tularensis and the host are slowly being elucidated. Microarray technology was used to further characterise the response of Balb/c mice after inhalation of the virulent F. tularensis , SchuS4. The validated array data
Autor:
Philippe Thullier, Gareth D. Griffiths
Publikováno v:
Clinical Toxicology. 47:643-650
It is extremely important that diagnosis of persons exposed to ricin be achieved in a timely fashion for triage and appropriate treatment. A sensitive and specific immunochromatographic test (ICT) for ricin has been developed for this purpose and rep
Autor:
A. Brown, Doreen Hooi, Leah Scott, P. C. Pearce, David I. Pritchard, Rebecca J. Hornby, Gareth D. Griffiths
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 78:936-945
Patent and pathologic infections of the human hookworm Necator americanus were established in the common marmoset (Callithrix jacchus). In a pilot study, a laboratory strain of N. americanus was compared with a fresh field isolate. Pathology was more
Publikováno v:
Inhalation Toxicology. 19:873-887
Ricin is a toxin and seed protein produced by the castor oil plant, Ricinus communis. The toxin is a dimeric protein consisting of an enzymic A chain and a B chain with lectin properties aiding the uptake of the whole molecule into cells. Ricin has b
Autor:
Stephen J. Wilson, E. A. M. Scott, K.E. Williams, Gareth D. Griffiths, S. Chamberlain, A. J. Smith, T.M. Mann, A. P. Bowditch, P. C. Pearce
Publikováno v:
Pharmacology Biochemistry and Behavior. 84:282-293
Following active service during the 1990/1991 Gulf conflict, a number of UK and US veterans presented with a diverse range of symptoms, collectively known as Gulf Veterans' Illnesses (GVI). The administration of vaccines and/or the pretreatment again