Weekly Oral Tenofovir Alafenamide Protects Macaques from Vaginal and Rectal Simian HIV Infection.

Autor: Massud I; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Nishiura K; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Ruone S; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Holder A; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Dinh C; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Lipscomb J; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Mitchell J; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Khalil GM; Quantitative Sciences and Data Management Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA., Heneine W; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Garcia-Lerma JG; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Dobard CW; Laboratory Branch, Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

Publikováno v: Pharmaceutics [Pharmaceutics] 2024 Mar 11; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 11.

Genital Immune Cell Activation and Tenofovir Gel Efficacy: A Case-Control Study.

Autor: Liebenberg LJP; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Passmore JAS; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; National Health Laboratory Service, Cape Town, South Africa., Osman F; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa., Jewanraj J; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Mtshali A; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Garcia-Lerma JG; Division of HIV/AIDS Prevention, National Center for HIV/ AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Heneine W; Division of HIV/AIDS Prevention, National Center for HIV/ AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Holder A; Division of HIV/AIDS Prevention, National Center for HIV/ AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Archary D; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Ngcapu S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Sivro A; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Mansoor LE; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa., Abdool Karim Q; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA., Abdool Karim SS; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA., McKinnon LR; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Sep 29; Vol. 75 (6), pp. 1088-1091.

Tenofovir Alafenamide for HIV Prevention: Review of the Proceedings from the Gates Foundation Long-Acting TAF Product Development Meeting.

Autor: Romano JW; NWJ Group, LLC., Wayne, Pennsylvania, USA., Baum MM; Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, USA., Demkovich ZR; RTI International, Durham, North Carolina, USA., Diana F; FJD-CMC Consulting, LLC., Ocean City, New Jersey, USA., Dobard C; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Feldman PL; Intarcia Therapeutics, Inc., Research Triangle Park, North Carolina, USA., Garcia-Lerma JG; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Grattoni A; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas, USA., Gunawardana M; Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, USA., Ho DK; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Hope TJ; Department of Cell and Developmental Biology, Northwestern University, Chicago, Illinois, USA., Massud I; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Milad M; Milad Pharmaceutical Consulting, Plymouth, Michigan, USA., Moss JA; Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, USA., Pons-Faudoa FP; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas, USA., Roller S; Intarcia Therapeutics, Inc., Research Triangle Park, North Carolina, USA., van der Straten A; Women's Global Health Imperative, RTI International, Berkeley, California, USA.; Department of Medicine, Center for AIDS Prevention Study (CAPS), UCSF, San Francisco, California, USA., Srinivasan S; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Veazey RS; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA., Zane D; Intarcia Therapeutics, Inc., Heyward, California, USA.

Publikováno v: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2021 Jun; Vol. 37 (6), pp. 409-420.

Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women.

Autor: McKinnon LR; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa., Liebenberg LJ; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa., Yende-Zuma N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa., Archary D; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa., Ngcapu S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa., Sivro A; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa., Nagelkerke N; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada., Garcia Lerma JG; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Kashuba AD; Eschelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Masson L; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa., Mansoor LE; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa., Karim QA; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA., Karim SSA; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Department of Epidemiology, Columbia University, New York, New York, USA., Passmore JS; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; National Health Laboratory Service, Cape Town, South Africa.

Publikováno v: Nature medicine [Nat Med] 2018 May; Vol. 24 (4), pp. 491-496. Date of Electronic Publication: 2018 Feb 26.

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