Portable, low-field magnetic resonance imaging for evaluation of Alzheimer's disease.

Autor: Sorby-Adams AJ; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Guo J; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Laso P; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kirsch JE; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Zabinska J; Department of Neurology, Center for Brain & Mind Health, Yale New Haven Hospital and Yale School of Medicine, New Haven, CT, USA., Garcia Guarniz AL; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Schaefer PW; Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Payabvash S; Division of Neuroradiology, Department of Radiology and Biomedical Imaging, Yale New Haven Hospital and Yale University School of Medicine, New Haven, CT, USA., de Havenon A; Department of Neurology, Center for Brain & Mind Health, Yale New Haven Hospital and Yale School of Medicine, New Haven, CT, USA., Rosen MS; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Sheth KN; Department of Neurology, Center for Brain & Mind Health, Yale New Haven Hospital and Yale School of Medicine, New Haven, CT, USA., Gomez-Isla T; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Iglesias JE; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kimberly WT; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. wtkimberly@mgh.harvard.edu.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. wtkimberly@mgh.harvard.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Dec 02; Vol. 15 (1), pp. 10488. Date of Electronic Publication: 2024 Dec 02.

Diffusion-Weighted Imaging Fluid-Attenuated Inversion Recovery Mismatch on Portable, Low-Field Magnetic Resonance Imaging Among Acute Stroke Patients.

Autor: Sorby-Adams A; Department of Neurology and the Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Guo J; Department of Neurology and the Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., de Havenon A; Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, CT, USA., Payabvash S; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA., Sze G; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA., Pinter NK; Department of Radiology, Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.; Department of Neurosurgery, Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA., Jaikumar V; Department of Neurosurgery, Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA., Siddiqui A; Department of Neurosurgery, Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA., Baldassano S; Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Garcia-Guarniz AL; Department of Neurology and the Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Zabinska J; Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, CT, USA., Lalwani D; Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, CT, USA., Peasley E; Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, CT, USA., Goldstein JN; Department of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Nelson OK; Department of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Schaefer PW; Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Wira CR 3rd; Department of Emergency Medicine, Yale New Haven Hospital and Yale School of Medicine, New Haven, CT, USA., Pitts J; Hyperfine Incorporated, Guilford, CT, USA., Lee V; Wexner Medical Center, Ohio State University, Columbus, OH, USA., Muir KW; School of Psychology and Neuroscience, University of Glasgow, Glasgow, UK., Nimjee SM; Wexner Medical Center, Ohio State University, Columbus, OH, USA., Kirsch J; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Iglesias JE; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Center for Medical Image Computing, University College London, London, UK.; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA., Rosen MS; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Sheth KN; Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, CT, USA., Kimberly WT; Department of Neurology and the Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Publikováno v: Annals of neurology [Ann Neurol] 2024 Aug; Vol. 96 (2), pp. 321-331. Date of Electronic Publication: 2024 May 13.

Plasma Metabolites and Life's Simple 7 in REGARDS.

Autor: Kijpaisalratana N; Department of Neurology, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (N.K., Z.A., W.T.K.).; Division of Neurology, Department of Medicine (N.K.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; Division of Academic Affairs (N.K.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Ament Z; Department of Neurology, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (N.K., Z.A., W.T.K.).; Department of Neurology, Massachusetts General Hospital, Boston (Z.A., A.-L.G.G., W.T.K.)., Patki A; Department of Epidemiology (A.P., A.C.J., C.A.C., M.R.I.), School of Public Health, University of Alabama at Birmingham., Bhave VM; Harvard Medical School, Boston, MA (V.M.B., W.T.K.)., Jones AC; Department of Epidemiology (A.P., A.C.J., C.A.C., M.R.I.), School of Public Health, University of Alabama at Birmingham., Couch CA; Department of Epidemiology (A.P., A.C.J., C.A.C., M.R.I.), School of Public Health, University of Alabama at Birmingham., Garcia Guarniz AL; Department of Neurology, Massachusetts General Hospital, Boston (Z.A., A.-L.G.G., W.T.K.)., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington (M.C.)., Long DL; Department of Biostatistics (D.L.L., S.E.J.), School of Public Health, University of Alabama at Birmingham., Judd SE; Department of Biostatistics (D.L.L., S.E.J.), School of Public Health, University of Alabama at Birmingham., Irvin MR; Department of Epidemiology (A.P., A.C.J., C.A.C., M.R.I.), School of Public Health, University of Alabama at Birmingham., Kimberly WT; Department of Neurology, Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (N.K., Z.A., W.T.K.).; Department of Neurology, Massachusetts General Hospital, Boston (Z.A., A.-L.G.G., W.T.K.).; Harvard Medical School, Boston, MA (V.M.B., W.T.K.).

Publikováno v: Stroke [Stroke] 2024 May; Vol. 55 (5), pp. 1191-1199. Date of Electronic Publication: 2024 Mar 14.

Gut microbiota-associated metabolites and risk of ischemic stroke in REGARDS.

Autor: Ament Z; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Patki A; Department of Epidemiology, School of Public Health at the University of Alabama at Birmingham, Birmingham, AL, USA., Bhave VM; Harvard Medical School, Boston, MA, USA., Chaudhary NS; Department of Epidemiology, School of Public Health at the University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Garcia Guarniz AL; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Kijpaisalratana N; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Division of Neurology, Department of Medicine and Division of Academic Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Judd SE; Department of Biostatistics, School of Public Health at the University of Alabama at Birmingham, Birmingham, AL, USA., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Long DL; Department of Biostatistics, School of Public Health at the University of Alabama at Birmingham, Birmingham, AL, USA., Irvin MR; Department of Epidemiology, School of Public Health at the University of Alabama at Birmingham, Birmingham, AL, USA., Kimberly WT; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2023 Jul; Vol. 43 (7), pp. 1089-1098. Date of Electronic Publication: 2023 Mar 08.

Nucleosides Associated With Incident Ischemic Stroke in the REGARDS and JHS Cohorts.

Autor: Ament Z; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Patki A; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Chaudhary N; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Bhave VM; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Garcia Guarniz AL; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Gao Y; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Gerszten RE; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Correa A; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Judd SE; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Cushman M; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Long DL; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Irvin MR; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington., Kimberly WT; From the Center for Genomic Medicine, Harvard Medical School (Z.A., W.T.K.), and Department of Neurology (Z.A., A.-L.G.G., W.T.K.), Massachusetts General Hospital, Boston; Departments of Epidemiology (A.P., N.C., R.M.I.) and Biostatistics (S.E.J., L.L.), School of Public Health, University of Alabama at Birmingham; Harvard Medical School (V.M.B.), Boston, MA; The Jackson Heart Study (Y.G., A.C.), University of Mississippi Medical Center, Jackson; Department of Medicine (R.E.G.), Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington.

Publikováno v: Neurology [Neurology] 2022 May 24; Vol. 98 (21), pp. e2097-e2107. Date of Electronic Publication: 2022 Mar 09.