N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents

Autor: Khelifi, Ilhem, Naret, Timothée, Hamze, Abdallah, Bignon, Jérome, Levaique, Hélène, Garcia Alvarez, Maria Concepcion, Dubois, Joëlle, Provot, Olivier, Alami, Mouad

Publikováno v: In European Journal of Medicinal Chemistry 15 April 2019 168:176-188

Overexpression of the natural tetrapeptide acetyl- N-ser-asp-lys-pro derived from thymosin β4 in neoplastic diseases.

Autor: Liu, Jian‐Miao¹ (AUTHOR), Garcia‐Alvarez, Maria‐Concepcion¹ (AUTHOR), Bignon, Jerome¹ (AUTHOR), Kusinski, Michal² (AUTHOR), Kuzdak, Krzysztof² (AUTHOR), Riches, Andrew³ (AUTHOR), Wdzieczak‐Bakala, Joanna¹ (AUTHOR)

Publikováno v: Annals of the New York Academy of Sciences. Apr2010, Vol. 1194 Issue 1, p53-59. 7p. 4 Graphs.

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Overexpression of the natural tetrapeptide acetyl-N-ser-asp-lys-pro derived from thymosin beta4 in neoplastic diseases

Autor: Liu, Jian-Miao, Garcia-Alvarez, Maria-Concepcion, Bignon, Jerome, Kusinski, Michal, Kuzdak, Krzysztof, Riches, Andrew, Wdzieczak-Bakala, Joanna

Publikováno v: Annals of the New York Academy of Sciences
Annals of the New York Academy of Sciences, Wiley, 2010, 1194, pp.53-59. ⟨10.1111/j.1749-6632.2010.05488.x⟩

International audience; The natural tetrapeptide acetyl-ser-asp-lys-pro (AcSDKP) is formed in vivo by enzymatic cleavage of the N terminus of thymosin beta4 by prolyl oligopeptidase (POP). Recently, AcSDKP was shown to promote angiogenesis. Because o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bfb88e43e03cc84cc47a09dd601b33ee
https://pubmed.ncbi.nlm.nih.gov/20536450

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