Directing novel ChoKα1 inhibitors using MamC-mediated biomimetic magnetic nanoparticles: a way to improve specificity and efficiency.

Autor: Sola-Leyva A; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada 18071, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada 18014, Spain. Electronic address: albertosola@ugr.es., Jabalera Y; Department of Microbiology, Faculty of Sciences, University of Granada, Granada 18071, Spain. Electronic address: yjabalera@ugr.es., Jimenez-Carretero M; Department of Microbiology, Faculty of Sciences, University of Granada, Granada 18071, Spain. Electronic address: monicajc@correo.ugr.es., Lázaro M; NanoMag Lab. Department of Applied Physic, Faculty of Science, University of Granada, Granada 18071, Spain., Pozo-Gualda T; Department of Microbiology, Faculty of Sciences, University of Granada, Granada 18071, Spain., García-Vargas PJ; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada 18071, Spain., Luque-Navarro PM; Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada 18071, Spain., Fasiolo A; Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada 18071, Spain., López-Cara LC; Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada 18071, Spain. Electronic address: lcarlotalopez@ugr.es., Iglesias GR; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada 18014, Spain; NanoMag Lab. Department of Applied Physic, Faculty of Science, University of Granada, Granada 18071, Spain; MNat Unit of Excellence, University of Granada, Granada 18071, Spain. Electronic address: iglesias@ugr.es., Paz Carrasco-Jiménez M; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada 18071, Spain. Electronic address: mpazcj@ugr.es., Jiménez-López C; Department of Microbiology, Faculty of Sciences, University of Granada, Granada 18071, Spain. Electronic address: cjl@ugr.es.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107693. Date of Electronic Publication: 2024 Aug 03.