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Association between missense variants of uncertain significance in the CHEK2 gene and hereditary breast cancer: a cosegregation and bioinformatics analysis.

Autor: Alonso N; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, Hospital San Pedro, Logroño, Spain., Menao S; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Biochemistry Department, University Hospital Lozano Blesa, Zaragoza, Spain., Lastra R; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain., Arruebo M; Biochemistry Department, University Hospital Lozano Blesa, Zaragoza, Spain., Bueso MP; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain., Pérez E; Breast Unit, University Hospital Lozano Blesa, Zaragoza, Spain., Murillo ML; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain., Álvarez M; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain., Alonso A; Biochemistry Department, University Hospital Arnau de Vilanova, Lleida, Spain., Rebollar S; Biochemistry Department, University Hospital Lozano Blesa, Zaragoza, Spain., Cruellas M; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital of Valld'Hebron, and Valld'Hebron Institute of Oncology, Barcelona, Spain., Arribas D; General Surgery Department, University Hospital Lozano Blesa, Zaragoza, Spain., Ramos M; Biochemistry Department, University Hospital Lozano Blesa, Zaragoza, Spain., Isla D; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain., Galano-Frutos JJ; Department of Biochemistry, Molecular and Cell Biology, Faculty of Science, University of Zaragoza, Zaragoza, Spain.; Biocomputation and Complex Systems Physics Institute (BIFI), Joint Units BIFI-IQFR (CSIC) and GBs-CSIC, University of Zaragoza, Zaragoza, Spain., García-Cebollada H; Department of Biochemistry, Molecular and Cell Biology, Faculty of Science, University of Zaragoza, Zaragoza, Spain.; Biocomputation and Complex Systems Physics Institute (BIFI), Joint Units BIFI-IQFR (CSIC) and GBs-CSIC, University of Zaragoza, Zaragoza, Spain., Sancho J; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Department of Biochemistry, Molecular and Cell Biology, Faculty of Science, University of Zaragoza, Zaragoza, Spain.; Biocomputation and Complex Systems Physics Institute (BIFI), Joint Units BIFI-IQFR (CSIC) and GBs-CSIC, University of Zaragoza, Zaragoza, Spain., Andrés R; Aragon Health Research Institute (IIS Aragón), Zaragoza, Spain.; Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain.

Publikováno v: Frontiers in genetics [Front Genet] 2024 Feb 27; Vol. 14, pp. 1274108. Date of Electronic Publication: 2024 Feb 27 (Print Publication: 2023).