Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials.

Autor: Río P; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Zubicaray J; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Pediatric Hematology and Oncology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Foundation for the Biomedical Research, Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Navarro S; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Gálvez E; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Pediatric Hematology and Oncology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Foundation for the Biomedical Research, Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Sánchez-Domínguez R; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Nicoletti E; Rocket Pharmaceuticals, Cranbury, NJ, USA., Sebastián E; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Pediatric Hematology and Oncology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Foundation for the Biomedical Research, Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Rothe M; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany., Pujol R; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Institut de Recerca Sant Pau, Universitat Autónoma de Barcelona, Barcelona, Spain; Unit of Genomic Medicine, Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Bogliolo M; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Institut de Recerca Sant Pau, Universitat Autónoma de Barcelona, Barcelona, Spain; Serra Hunter Fellow, Department of Genetics and Microbiology, Faculty of Biosciences, Universitat Autònoma de Barcelona, Barcelona, Spain; Unit of Genomic Medicine, Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., John-Neek P; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany., Bastone AL; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany., Schambach A; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Wang W; Genwerk, Heidelberg, Germany., Schmidt M; Genwerk, Heidelberg, Germany., Larcher L; Université Paris Cité, Inserm, CNRS, Hôpital Saint-Louis, APHP, Paris, France., Segovia JC; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Yáñez RM; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Alberquilla O; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Díez B; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Fernández-García M; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., García-García L; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain., Ramírez M; Pediatric Hematology and Oncology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Sanitary Research Institute Fundación La Princesa, Madrid, Spain., Galy A; Genethon, UMR_S951, Université Paris-Saclay, Univ Evry, Inserm, Evry-Courcouronnes, France., Lefrere F; Hôpital Universitaire Necker Enfants-Malades, Assistance Publique Hôpitaux de Paris GHU Paris Centre, Université Paris Cité, Paris, France; Centre D'Investigation Clinique en Biotherapie INSERM, Institut Imagine, Paris, France., Cavazzana M; Hôpital Universitaire Necker Enfants-Malades, Assistance Publique Hôpitaux de Paris GHU Paris Centre, Université Paris Cité, Paris, France; Centre D'Investigation Clinique en Biotherapie INSERM, Institut Imagine, Paris, France., Leblanc T; Robert-Debré University Hospital (APHP and Université Paris Cité), Paris, France., García de Andoin N; Donostia Universitary Hospital, San Sebastián, Spain; Biogipuzkoa Health Research Institute, San Sebastián, Spain., López-Almaraz R; Cruces Universitary Hospital, Barakaldo, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Catalá A; Hospital Sant Joan de Déu, Barcelona, Spain; Research Institute Sant Joan de Déu, Barcelona, Spain., Barquinero J; Vall d'Hebron Institut de Recerca, Barcelona, Spain., Rodríguez-Perales S; Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Rao G; Rocket Pharmaceuticals, Cranbury, NJ, USA., Surrallés J; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Institut de Recerca Sant Pau, Universitat Autónoma de Barcelona, Barcelona, Spain; Unit of Genomic Medicine, Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Soulier J; Université Paris Cité, Inserm, CNRS, Hôpital Saint-Louis, APHP, Paris, France., Díaz-de-Heredia C; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Vall d'Hebron Institut de Recerca, Barcelona, Spain; Pediatric Haematology and Oncology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Schwartz JD; Rocket Pharmaceuticals, Cranbury, NJ, USA., Sevilla J; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Pediatric Hematology and Oncology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Foundation for the Biomedical Research, Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Bueren JA; Biomedical Innovation Unit, Center for Research on Energy, Environment and Technology (CIEMAT), Madrid, Spain; Biomedical Network Research Center for Rare Diseases (CIBERER), Madrid, Spain; Sanitary Research Institute Fundación Jiménez Díaz (U.A.M), Madrid, Spain. Electronic address: juan.bueren@ciemat.es.

Publikováno v: Lancet (London, England) [Lancet] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.

Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets.

Autor: Nunes-Xavier CE; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Zaldumbide L; Department of Pathology, Cruces University Hospital, Barakaldo, Spain., Mosteiro L; Department of Pathology, Cruces University Hospital, Barakaldo, Spain., López-Almaraz R; Pediatric Oncology and Hematology, Cruces University Hospital, Barakaldo, Spain., García de Andoin N; Unit of Pediatric Oncohematology, Donostia University Hospital, San Sebastian, Spain., Aguirre P; Department of Pathology, Donostia University Hospital, San Sebastian, Spain., Emaldi M; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Torices L; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., López JI; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Pathology, Cruces University Hospital, Barakaldo, Spain., Pulido R; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Dec 08; Vol. 9, pp. 811297. Date of Electronic Publication: 2021 Dec 08 (Print Publication: 2021).

1399 - Involvement of SNPS in CDKN2A/B locus in childhood acute lymphoblastic leukemia susceptibility in the Spanish population

Autor: Gutierrez-Camino, A., Martin-Guerrero, I., Garcia de Andoin, N., Navajas, A., Sastre, A., Carbone Baneres, A., Astigarraga, I., Garcia-Orad, A.

Publikováno v: In European Journal of Cancer February 2017 72 Supplement 1:S144-S144

1398 - SNPS in microRNAs associated with methotrexate plasma levels in Spanish children with acute lymphoblastic leukemia

Autor: Umerez, M., Gutierrez-Camino, A., Martin-Guerrero, I., Garcia De Andoin, N., Sastre, A., Navajas, A., Astigarraga, I., Garcia-Orad, A.

Publikováno v: In European Journal of Cancer February 2017 72 Supplement 1:S143-S143

Pharmacoepigenetics in childhood acute lymphoblastic leukemia: involvement of miRNA polymorphisms in hepatotoxicity.

Autor: Gutierrez-Camino A; Department of Genetics, Physic Anthropology & Animal Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain., Umerez M; Department of Genetics, Physic Anthropology & Animal Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain., Santos B; Department of Genetics, Physic Anthropology & Animal Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain., Martin-Guerrero I; Department of Genetics, Physic Anthropology & Animal Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain., García de Andoin N; Department of Pediatrics, University Hospital Donostia, San Sebastian, Spain.; Department of Pediatrics, University of the Basque Country, UPV/EHU, Leioa, Spain., Sastre A; Department of Oncohematology, University Hospital La Paz, Madrid, Spain., Navajas A; Department of Pediatrics, University Hospital Cruces, Barakaldo, Spain.; BioCruces Health Research Institute, Barakaldo, Spain., Astigarraga I; Department of Pediatrics, University of the Basque Country, UPV/EHU, Leioa, Spain.; Department of Pediatrics, University Hospital Cruces, Barakaldo, Spain.; BioCruces Health Research Institute, Barakaldo, Spain., Garcia-Orad A; Department of Genetics, Physic Anthropology & Animal Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain.; BioCruces Health Research Institute, Barakaldo, Spain.

Publikováno v: Epigenomics [Epigenomics] 2018 Apr 01; Vol. 10 (4), pp. 409-417. Date of Electronic Publication: 2018 Mar 23.