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Akademický článek

P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-Derived Cardiomyocytes in 3-Dimensional Suspension Culture Via FOXO-FOXM1 Regulation.

Autor: Velayutham N; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA.; Department of Cardiology Boston Children's Hospital Boston MA USA., Elwell HLT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Zhuo Z; Bioinformatics Core, Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA USA., Rüland L; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Elcure Alvarez F; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Frontini S; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Rodriguez Carreras Y; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Eichholtz M; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Ricci-Blair E; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Shaw JY; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Bouffard AH; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Sokol M; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Mancheño Juncosa E; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Rhoades S; Ginkgo Bioworks Boston MA USA., van den Berg D; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Kreymerman A; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Aoyama J; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA., Höfflin J; Ginkgo Bioworks Boston MA USA., Ryan H; Ginkgo Bioworks Boston MA USA., Ho Sui S; Bioinformatics Core, Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA USA., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute Harvard University Cambridge MA USA.; Division of Cardiovascular Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA USA.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2024 Jul 02; Vol. 13 (13), pp. e033155. Date of Electronic Publication: 2024 Jun 27.

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Akademický článek

Tissue-embedded stretchable nanoelectronics reveal endothelial cell-mediated electrical maturation of human 3D cardiac microtissues.

Autor: Lin Z; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA., Garbern JC; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Department of Cardiology, Boston Children's Hospital, Boston, MA, USA., Liu R; School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA., Li Q; School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA., Mancheño Juncosa E; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Elwell HLT; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Sokol M; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Aoyama J; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Deumer US; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Hsiao E; School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA., Sheng H; School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA., Lee RT; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Liu J; School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA.

Publikováno v: Science advances [Sci Adv] 2023 Mar 10; Vol. 9 (10), pp. eade8513. Date of Electronic Publication: 2023 Mar 08.

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Akademický článek

Senescence mechanisms and targets in the heart.

Autor: Chen MS; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA 02115, USA., Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA.; Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2022 Mar 25; Vol. 118 (5), pp. 1173-1187.

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Akademický článek

Heart regeneration: 20 years of progress and renewed optimism.

Autor: Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA; Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA 02115, USA. Electronic address: richard_lee@harvard.edu.

Publikováno v: Developmental cell [Dev Cell] 2022 Feb 28; Vol. 57 (4), pp. 424-439.

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Akademický článek

Mitochondria and metabolic transitions in cardiomyocytes: lessons from development for stem cell-derived cardiomyocytes.

Autor: Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA, 02138, USA.; Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA, 02138, USA. richard_lee@harvard.edu.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA. richard_lee@harvard.edu.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2021 Mar 12; Vol. 12 (1), pp. 177. Date of Electronic Publication: 2021 Mar 12.

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Akademický článek

Pluripotent stem cell-derived cardiomyocytes for treatment of cardiomyopathic damage: Current concepts and future directions.

Autor: Garbern JC; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, United States; Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, United States., Escalante GO; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, United States., Lee RT; Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, United States; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, MA 02115, United States. Electronic address: richard_lee@harvard.edu.

Publikováno v: Trends in cardiovascular medicine [Trends Cardiovasc Med] 2021 Feb; Vol. 31 (2), pp. 85-90. Date of Electronic Publication: 2020 Jan 14.

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