An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals

Autor: Anna Offersgaard, Carlos R. Duarte Hernandez, Yuyong Zhou, Zhe Duan, Karen Anbro Gammeltoft, Katrine T. Hartmann, Ulrik Fahnøe, Pavel Marichal-Gallardo, Garazi Peña Alzua, Alexander P. Underwood, Christina Sølund, Nina Weis, Jesper Hansen Bonde, Jan P. Christensen, Gabriel K. Pedersen, Henrik Elvang Jensen, Kenn Holmbeck, Jens Bukh, Judith Margarete Gottwein

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

Abstract Rapidly waning immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires continued global access to affordable vaccines. Globally, inactivated SARS-CoV-2 vaccines have been widely used during the SARS-CoV-2 pande

Externí odkaz: https://doaj.org/article/7364ae58a77642cc80f00f3bfff1ca99

Time and temperature dependent analytical stability of dry-collected Evalyn HPV self-sampling brush for cervical cancer screening

Autor: Ditte Møller Ejegod, Helle Pedersen, Garazi Peña Alzua, Camilla Pedersen, Jesper Bonde

Publikováno v: Papillomavirus Research, Vol 5, Iss , Pp 192-200 (2018)

As a new initiative, HPV self-sampling to non-attenders using the dry Evalyn self-sampling brush is offered in the Capital Region of Denmark. The use of a dry brush is largely uncharted territory in terms of analytical stability. In this study we aim

Externí odkaz: https://doaj.org/article/b964d8387e0044edb84f45dccd25918f

Identification of novel neutralizing determinants for protection against HCV

Autor: Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein

Publikováno v: Alzua, G P, Pihl, A F, Offersgaard, A, Velázquez-Moctezuma, R, Duarte Hernandez, C R, Augestad, E H, Fahnøe, U, Mathiesen, C K, Krarup, H, Law, M, Prentoe, J, Bukh, J & Gottwein, J M 2023, ' Identification of novel neutralizing determinants for protection against HCV ', Hepatology, vol. 73, no. 3, pp. 982-996 . https://doi.org/10.1002/hep.32772
Alzua, G P, Pihl, A F, Offersgaard, A, Velázquez-Moctezuma, R, Hernandez, C R D, Augestad, E H, Fahnøe, U, Mathiesen, C K, Krarup, H, Law, M, Prentoe, J, Bukh, J & Gottwein, J M 2023, ' Identification of novel neutralizing determinants for protection against HCV ', Hepatology, vol. 77, no. 3, pp. 982-996 . https://doi.org/10.1002/hep.32772

BACKGROUND AND AIMS: HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine. N-linked glycosylation of viral envelope proteins is a key mechanism for such evasio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee8ddda5099418631770b24f323c860
https://curis.ku.dk/portal/da/publications/identification-of-novel-neutralizing-determinants-for-protection-against-hcv(8ae9404e-763e-4513-aa0e-d6bc1800cc97).html