Pan-cancer antagonistic inhibition pattern of ATM-driven G2/M checkpoint pathway vs other DNA repair pathways.

Autor: Zolotovskaia MA; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; Omicsway Corp., Walnut, CA, 91789, USA. Electronic address: zolotovskaia.ma@mipt.ru., Modestov AA; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Suntsova MV; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; World-Class Research Center 'Digital biodesign and personalized healthcare', Sechenov First Moscow State Medical University, Moscow, Russia., Rachkova AA; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Koroleva EV; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia., Poddubskaya EV; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Sekacheva MI; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Tkachev VS; Oncobox Ltd., Moscow 121205, Russia., Garazha AV; Omicsway Corp., Walnut, CA, 91789, USA; Oncobox Ltd., Moscow 121205, Russia., Glusker AA; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Seryakov AP; Department of Oncology, Medical Holding SM-Clinic, 105120 Moscow, Russia., Vladimirova US; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Rumiantsev PO; Department of Nuclear Medicine, Endocrinology Research Centre, Moscow 117312, Russia., Moisseev AA; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia., Zharkov DO; Laboratory for Protein Engineering, Novosibirsk State University, Novosibirsk 630090, Russia; Laboratory for Genomic and Protein Engineering, SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia., Kuzmin DV; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia., Zhao X; Core Laboratory, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao 266042 China., Prassolov VS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia., Shegay PV; National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, 249036 Obninsk, Russia., Li X; UCLA Technology Center for Genomics & Bioinformatics, Department of Pathology & Laboratory Medicine, Los Angeles, CA 90095, USA., Steinbichler TB; Tyrolean Cancer Research Institute, Innsbruck, Austria., Kim E; Clinic for Neurosurgery, Laboratory of Experimental Neurooncology, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany., Sorokin MI; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; Omicsway Corp., Walnut, CA, 91789, USA; Laboratory for Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia; Laboratory for Genomic Analysis of Signaling Systems, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia., Wang Y; Core Laboratory, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao 266042 China. Electronic address: yewang@qdu.edu.cn., Buzdin AA; Laboratory for Translational Genomic Bioinformatics, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region 141701, Russia; World-Class Research Center 'Digital biodesign and personalized healthcare', Sechenov First Moscow State Medical University, Moscow, Russia; Laboratory for Genomic Analysis of Signaling Systems, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia; PathoBiology Group, European Organization for Research and Treatment of Cancer (EORTC), Brussels, Belgium.

Publikováno v: DNA repair [DNA Repair (Amst)] 2023 Mar; Vol. 123, pp. 103448. Date of Electronic Publication: 2023 Jan 13.

Gene Expression Signature in Diagnosis of Endometriosis

Autor: Aznaurova, YB, Adamyan, LV, Stepanian, AA, Garazha, AV, Buzdin, AA

Publikováno v: In The Journal of Minimally Invasive Gynecology November-December 2019 26(7) Supplement:S4-S5

Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs.

Autor: Zolotovskaia MA; Oncobox Ltd., Moscow, Russia.; Department of Oncology, Hematology and Radiotherapy of Pediatric Faculty, Pirogov Russian National Research Medical University, Moscow, Russia., Sorokin MI; The Laboratory of Clinical Bioinformatics, IM Sechenov First Moscow State Medical University, Moscow, Russia.; Omicsway Corp., Walnut, CA, United States.; Science-Educational Center Department, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Emelianova AA; Science-Educational Center Department, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Borisov NM; The Laboratory of Clinical Bioinformatics, IM Sechenov First Moscow State Medical University, Moscow, Russia.; Omicsway Corp., Walnut, CA, United States., Kuzmin DV; Science-Educational Center Department, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Borger P; Laboratory of the Swiss Hepato-Pancreato-Biliary, Department of Surgery, Transplantation Center, University Hospital Zurich, Zurich, Switzerland., Garazha AV; Omicsway Corp., Walnut, CA, United States., Buzdin AA; Oncobox Ltd., Moscow, Russia.; The Laboratory of Clinical Bioinformatics, IM Sechenov First Moscow State Medical University, Moscow, Russia.; Science-Educational Center Department, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2019 Jan 23; Vol. 10, pp. 1. Date of Electronic Publication: 2019 Jan 23 (Print Publication: 2019).

Potentialities of MicroRNA Diagnosis in Patients with Bladder Cancer.

Autor: Shegay PV; National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia. dr.shegay@mail.ru., Zhavoronkov AA; First Oncology Research and Advisory Center (FORAC), Moscow, Russia., Gaifullin NM; M. V. Lomonosov Moscow State University, Moscow, Russia., Vorob'ev NV; National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia., Alekseev BY; National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia., Popov SV; National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia., Garazha AV; First Oncology Research and Advisory Center (FORAC), Moscow, Russia., Buzdin AA; First Oncology Research and Advisory Center (FORAC), Moscow, Russia., Kaprin AD; National Medical Radiological Research Center, Ministry of Health of the Russian Federation, Moscow, Russia.

Publikováno v: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Nov; Vol. 164 (1), pp. 106-108. Date of Electronic Publication: 2017 Nov 09.

Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts.

Autor: Buzdin AA; a Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology , Moscow , Russia.; b Group for Genomic Regulation of Cell Signaling Systems, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry , Moscow , Russia.; c National Research Centre 'Kurchatov Institute', Centre for Convergence of Nano-, Bio-, Information and Cognitive Sciences and Technologies , Moscow , Russia., Artcibasova AV; a Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology , Moscow , Russia.; d Pathway Pharmaceuticals , Wan Chai, Hong Kong , Hong Kong SAR., Fedorova NF; e N.F. Gamaleya Federal Research Centre for Epidemiology and Microbiology of the Ministry of Health of the Russian Federation , Moscow , Russia., Suntsova MV; a Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology , Moscow , Russia.; b Group for Genomic Regulation of Cell Signaling Systems, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry , Moscow , Russia., Garazha AV; a Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology , Moscow , Russia.; f Moscow Institute of Physics and Technology , Dolgoprudny, Moscow region , Russia., Sorokin MI; g First Oncology Research and Advisory Center , Moscow , Russia., Allina D; f Moscow Institute of Physics and Technology , Dolgoprudny, Moscow region , Russia.; g First Oncology Research and Advisory Center , Moscow , Russia., Shalatonin M; h The Morozov Children's City Hospital , Moscow Russia., Borisov NM; c National Research Centre 'Kurchatov Institute', Centre for Convergence of Nano-, Bio-, Information and Cognitive Sciences and Technologies , Moscow , Russia.; g First Oncology Research and Advisory Center , Moscow , Russia., Zhavoronkov AA; a Laboratory of Bioinformatics, D. Rogachyov Federal Research Center of Pediatric Hematology, Oncology and Immunology , Moscow , Russia.; d Pathway Pharmaceuticals , Wan Chai, Hong Kong , Hong Kong SAR., Kovalchuk I; i Department of Biological Sciences , University of Lethbridge , Lethbridge , AB , Canada., Kovalchuk O; i Department of Biological Sciences , University of Lethbridge , Lethbridge , AB , Canada., Kushch AA; e N.F. Gamaleya Federal Research Centre for Epidemiology and Microbiology of the Ministry of Health of the Russian Federation , Moscow , Russia.

Publikováno v: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2016 Dec 16; Vol. 15 (24), pp. 3378-3389.