Výsledky vyhledávání - "Garayoa, M. (Mercedes)"

Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines

Autor: Paino, T. (Teresa), Sarasquete, M.E. (María E.), Paiva, B. (Bruno), Krzeminski, P. (Patryk), San-Segundo, L. (Laura), Corchete, L.A. (Luis A.), Redondo, A. (Alba), Garayoa, M. (Mercedes), García-Sanz, R. (Ramón), Gutierrez, N.C. (Norma C.), Ocio, E.M. (Enrique M.), San-Miguel, J.F. (Jesús F.)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease potentially due to the presence of resistant myeloma cancer stem cells (MM-CSC). Although the presence of clonogenic cells in MM was described three de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::eeaf305630970479dd885cb06086fbf4
https://hdl.handle.net/10171/38274

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Depressed adrenomedullin in the embryonic transforming growth factor-beta1 null mouse becomes elevated postnatally

Autor: Bodegas-Frías, E. (Elena), Martinez, A. (Alfredo), Ozbun, L.L. (Laurent L.), Garayoa, M. (Mercedes), Letterio, J.J. (John J.), Montuenga-Badia, L.M. (Luis M.), Jakowlew, S.B. (Sonia B.)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Transforming growth factor-beta (TGF-beta) and adrenomedullin are multifunctional regulatory proteins which are expressed in developing embryonic and adult tissues. Because of their colocalization, TGF-beta1 and adrenomedullin may be able to coordina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::20655d41330e30cadcd00b37916d505e
https://hdl.handle.net/10171/18814

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Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement

Autor: Ajona, D. (Daniel), Castaño, Z. (Z.), Garayoa, M. (Mercedes), Zudaire, E. (Enrique), Pajares, M.J. (María José), Martinez, A. (Alfredo), Cuttitta, F. (Frank), Montuenga-Badia, L.M. (Luis M.), Pio, R. (Rubén)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a23274d8a9b65fea99336d552f70ff93
https://hdl.handle.net/10171/18807

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Mitogen-Activated Protein Kinase Phosphatase-1 Is Overexpressed in Non-Small Cell Lung Cancer and Is an Independent Predictor of Outcome in Patients

Autor: Vicent, S. (Silvestre), Garayoa, M. (Mercedes), Lopez-Picazo, J.M. (José M.), Lozano, M.D. (María Dolores), Toledo, G. (Gemma), Thunnissen, F.B. (Frederick B.), Manzano, R.G. (Ramón G.), Montuenga-Badia, L.M. (Luis M.)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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An increase in the activity of the mitogen-activated protein kinases (MAPKs) has been correlated with a more malignant phenotype in several tumor models in vitro and in vivo. A key regulatory mechanism of the MAPKs [extracellular signal-regulated kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::336626119cc2cc56cc469ad5441f513d
https://hdl.handle.net/10171/18811

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Androgen-independent expression of adrenomedullin and peptidylglycine alpha-amidating monooxygenase in human prostatic carcinoma

Autor: Jimenez, N. (Nuria), Abasolo, I. (Ibane), Jongsma, J. (Johan), Calvo, A. (Alfonso), Garayoa, M. (Mercedes), Kwast, T.H. (Theodorus H. ) van der, Steenbrugge, G.J. (Gert J.) van, Montuenga-Badia, L.M. (Luis M.)

Publikováno v: Molecular Carcinogenesis, 38, 14-24. Wiley-Liss Inc.
Dadun. Depósito Académico Digital de la Universidad de Navarra
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Most of the locally advanced and metastatic prostate carcinomas (PCs) treated with antiandrogenic therapy eventually become refractory to this treatment. Locally produced factors may control prostate tumor biology after androgen withdrawal. Adrenomed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d9a358ded45559ae7a8a49f82722c639
https://hdl.handle.net/10171/20180

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Adrenomedullin functions as an important tumor survival factor in human carcinogenesis

Autor: Cuttitta, F. (Frank), Pio, R. (Rubén), Garayoa, M. (Mercedes), Zudaire, E. (Enrique), Julian, M. (Miguel), Elssasser, T. (T.), Montuenga-Badia, L.M. (Luis M.), Martinez, A. (Alfredo)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Adrenomedullin (AM) is a pluripotent regulatory peptide initially isolated from a human pheochromocytoma (adrenal tumor) and subsequently shown to play a critical role in cancer cell division, tumor neovascularization, and circumvention of programmed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c531bfa13489a65653316cb5c0732ae2
https://hdl.handle.net/10171/20182

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Adrenomedullin in mammalian embryogenesis

Autor: Garayoa, M. (Mercedes), Bodegas-Frías, E. (Elena), Cuttitta, F. (Frank), Montuenga-Badia, L.M. (Luis M.)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Here are summarized data supporting that adrenomedullin (AM) is a multifunctional factor involved in the complex regulatory mechanisms of mammalian development. During rodent embryogenesis, AM is first expressed in the heart, followed by a broader bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3a8c3c8f8dcebb512f3892fb635edebe
https://hdl.handle.net/10171/20187

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The role of adrenomedullin as a growth regulatory peptide in the normal and malignant setting

Autor: Martinez, A. (Alfredo), Walsh, T. (Thomas), Miller, M.J. (Mae Jean), Pio, R. (Rubén), Garayoa, M. (Mercedes), Montuenga-Badia, L.M. (Luis M.), Cuttitta, F. (Frank)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Adrenomedullin (AM ) is a recently discovered pluripo1ent peptide initially isolated fraro a human adrenal gland tumor (pheochromocytoma). Adrenomedullin has been shown to have an ancient origin with immunoreactive species fOWld in maromals, birds, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2e1634a075a6f6e61e3672c1ce47fb31
https://hdl.handle.net/10171/20167

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Malpighian tubules of Formica polyctena (Hymenoptera): light and electron microscopic study

Autor: Garayoa, M. (Mercedes), Villaro, A.C. (Ana Cristina), Montuenga-Badia, L.M. (Luis M.), Sesma, M.P. (María Pilar)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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The study of semithin (1 μ in thickness) and thin sections of Epon-embedded material reveals that Malpighian tubules of Formica polyctena are composed of a single cellular type throughout their length. No differentiated regions were observed. Ultras

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cb14452a4f6d94a330e656cf8c276d58
https://hdl.handle.net/10171/20123

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