Výsledky vyhledávání - "Garance Coquant"

Akademický článek

3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors

Autor: Garance Coquant, Doriane Aguanno, Loïc Brot, Christine Belloir, Julie Delugeard, Nathalie Roger, Hang-Phuong Pham, Loïc Briand, Marielle Moreau, Luisa de Sordi, Véronique Carrière, Jean-Pierre Grill, Sophie Thenet, Philippe Seksik

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule 3-oxo-C12:2-HSL, first identified in human gut microbiota, exerts anti-inflammatory

Externí odkaz: https://doaj.org/article/b8792f0195a14d089cac4c1d13deb817

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Akademický článek

Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity

Autor: Garance Coquant, Jean-Pierre Grill, Philippe Seksik

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Among numerous molecules found in the gut ecosystem, quorum sensing (QS) molecules represent an overlooked part that warrants highlighting. QS relies on the release of small molecules (auto-inducers) by bacteria that accumulate in the environment dep

Externí odkaz: https://doaj.org/article/b5e455d1c375409fa392b7ac42ef3b1d

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Akademický článek

Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells

Autor: Agathe Peyrottes, Garance Coquant, Loïc Brot, Dominique Rainteau, Philippe Seksik, Jean-Pierre Grill, Jean-Maurice Mallet

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 24, p 9448 (2020)

Background: Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD), the potential effects of these molecules on host cells have raised interest in the medical

Externí odkaz: https://doaj.org/article/8bc183c52be9498297f1a952e10f101e

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Gossip in the gut: Quorum sensing, a new player in the host-microbiota interactions

Autor: Philippe Seksik, Sophie Thenet, Doriane Aguanno, Jean-Pierre Grill, Nathan Grellier, Sandrine Pham, Véronique Carrière, Garance Coquant

Publikováno v: World Journal of Gastroenterology
World Journal of Gastroenterology, Baishideng Publishing Group Co. Limited, 2021, 27 (42), pp.7247-7270. ⟨10.3748/wjg.v27.i42.7247⟩
World Journal of Gastroenterology, 2021, 27 (42), pp.7247-7270. ⟨10.3748/wjg.v27.i42.7247⟩

International audience; Bacteria are known to communicate with each other and regulate their activities in social networks by secreting and sensing signaling molecules called autoinducers, a process known as quorum sensing (QS). This is a growing are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89aab3411006d0ada41daaf00953e1ca
https://pubmed.ncbi.nlm.nih.gov/34876787

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The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption

Autor: Jean-Pierre Grill, Céline Osinski, Philippe Seksik, Daniel Stockholm, Sophie Thenet, Véronique Carrière, Bárbara Graziela Postal, Garance Coquant, Margaux Wieckowski, Doriane Aguanno

Publikováno v: Tissue Barriers
article-version (VoR) Version of Record

The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major actors of the intestinal barrier, which is impaired in inflammatory bowel disease (IBD), along wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee536eec4432609de9f660d88a4be69
https://doi.org/10.1080/21688370.2020.1832877

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