ATXN3 controls DNA replication and transcription by regulating chromatin structure

Autor: Esperanza Hernández-Carralero, Elisa Cabrera, Gara Rodríguez-Torres, Yeray Hernández-Reyes, Abhay N Singh, Cristina Santa-María, José Miguel Fernández-Justel, Roel C Janssens, Jurgen A Marteijn, Bernd O Evert, Niels Mailand, María Gómez, Kristijan Ramadan, Veronique A J Smits, Raimundo Freire

Publikováno v: Hernández-Carralero, E, Cabrera, E, Rodríguez-Torres, G, Hernández-Reyes, Y, Singh, A N, Santa-María, C, Fernández-Justel, J M, Janssens, R C, Marteijn, J A, Evert, B O, Mailand, N, Gómez, M, Ramadan, K, Smits, V A J & Freire, R 2023, ' ATXN3 controls DNA replication and transcription by regulating chromatin structure ', Nucleic Acids Research, vol. 51, no. 11, pp. 5396–5413 . https://doi.org/10.1093/nar/gkad212

The deubiquitinating enzyme Ataxin-3 (ATXN3) contains a polyglutamine (PolyQ) region, the expansion of which causes spinocerebellar ataxia type-3 (SCA3). ATXN3 has multiple functions, such as regulating transcription or controlling genomic stability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aa7d5c4a33687a0e2797bef5f2c754
https://doi.org/10.1093/nar/gkad212