Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gar Kay Hui"'
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0288351 (2023)
FcγRI (CD64) is the only high-affinity Fcγ receptor found on monocytes, macrophages, eosinophils, neutrophils and dendritic cells. It binds immunoglobulin G (IgG) antibody-antigen complexes at its Fc region to trigger key immune responses. CD64 con
Externí odkaz:
https://doaj.org/article/65d310ba5b09425aaaaecc45d7472c60
Autor:
Paul A. Dalby, Lucy E. Rayner, Richard K. Heenan, Stephen J. Perkins, Jayesh Gor, Gar Kay Hui
Publikováno v:
Journal of Biological Chemistry. 290:8420-8438
The human IgG1 antibody subclass shows distinct properties compared with the IgG2, IgG3, and IgG4 subclasses and is the most exploited subclass in therapeutic antibodies. It is the most abundant subclass, has a half-life as long as that of IgG2 and I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15594e92db1aba4b4b9ecc6d826d9bcb
https://doi.org/10.1074/jbc.m114.631002
https://doi.org/10.1074/jbc.m114.631002
Autor:
Gar Kay, Hui, David W, Wright, Owen L, Vennard, Lucy E, Rayner, Melisa, Pang, See Cheng, Yeo, Jayesh, Gor, Karen, Molyneux, Jonathan, Barratt, Stephen J, Perkins
Publikováno v:
Biochemical Journal
Detailed analytical ultracentrifugation and X-ray/neutron scattering data and a new atomistic modelling approach revealed asymmetric extended solution structures for human IgA1 that account for its receptor-binding function. IgA1 with different hinge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72eb2c5849373fcfbf6812cfc9a567ed
https://pubmed.ncbi.nlm.nih.gov/26268558
https://pubmed.ncbi.nlm.nih.gov/26268558
Autor:
Rayner, Lucy E.1, Gar Kay Hui1, Jayesh Gor1, Heenan, Richard K.2, Dalby, Paul A.3, Perkins, Stephen J.1 s.perkins@ucl.ac.uk
Publikováno v:
Journal of Biological Chemistry. 7/25/2014, Vol. 289 Issue 30, p20740-20756. 17p.
Autor:
Stephen J. Perkins, Emre H. Brookes, Ruodan Nan, David W. Wright, Joseph E. Curtis, Gar Kay Hui
Publikováno v:
Biophysical Journal. (2):191a
Small angle X-ray and neutron scattering (SAS) experiments and molecular modelling offer powerful tools to understand protein behaviour in solution. SAS experiments have made huge strides in the last two decades due to improved instrumentation and so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87508532a93a890273a5b2e1c916049