Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Gap Ryol Lee"'
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract T helper type 9 (Th9) cells play important roles in immune responses by producing interleukin‐9 (IL‐9). Several transcription factors are responsible for Th9 cell differentiation; however, transcriptional regulation of Th9 cells is not f
Externí odkaz:
https://doaj.org/article/86f34fc2e3934eb6b5e1906acd966aa0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Regulatory T (Treg) cells maintain immune homeostasis by preventing abnormal or excessive immune responses. Histone deacetylase 6 (HDAC6) regulates expression of Foxp3, and thus, Treg cell differentiation; however, its role in Treg cell diff
Externí odkaz:
https://doaj.org/article/88373e9b81e24b689a2c49a6bfc84a9d
Autor:
Woo Ho Lee, Sung Woong Jang, Hyeong Su Kim, So Hee Kim, Jung In Heo, Ga Eul Kim, Gap Ryol Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 11, Pp 1-12 (2019)
Immunology: fanning the fires of airway inflammation A protein that regulates gene expression in immune cells may contribute to airway inflammation in asthma and allergies. A subset of immune cells known as Th9 cells plays a prominent role in these r
Externí odkaz:
https://doaj.org/article/58eb92b9f6a949aeb3ffdcbaedbe0bfb
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 7, Pp 1-15 (2019)
Autoimmunity: Revealing the genes behind immune cell responses The identification of a protein involved in the functioning of certain immune cells may inform future therapies for autoimmune diseases and cancer. Regulatory T cells (Treg) are immune ce
Externí odkaz:
https://doaj.org/article/90e1c49aeff9427193ede277c558ab2a
Autor:
Soo Seok Hwang, Sung Woong Jang, Min Kyung Kim, Lark Kyun Kim, Bong-Sung Kim, Hyeong Su Kim, Kiwan Kim, Wonyong Lee, Richard A. Flavell, Gap Ryol Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Treg control the magnitude of immune responses, but how these cells are controlled is less understood. Here the authors show that a transcriptional repressor YY1 inhibits Foxp3, the master regulator of Treg, by repressing its transcription, and by di
Externí odkaz:
https://doaj.org/article/4652ebf99d2c460eaee2534aba5dd274
Autor:
Gap Ryol Lee
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Regulatory T (Treg) cells maintain immune homeostasis by suppressing excessive immune responses. Treg cells induce tolerance against self- and foreign antigens, thus preventing autoimmunity, allergy, graft rejection, and fetus rejection during pregna
Externí odkaz:
https://doaj.org/article/0025a115cc984c339cac0a7376d9f501
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148576 (2016)
The T helper type 2 (Th2) locus control region (LCR) regulates Th2 cell differentiation. Several transcription factors bind to the LCR to modulate the expression of Th2 cytokine genes, but the molecular mechanisms behind Th2 cytokine gene regulation
Externí odkaz:
https://doaj.org/article/a0ab1ea585f14d4697cc54d4e2705010
Autor:
Hong-Jai Park, Do-Hyun Kim, Jin-Young Choi, Won-Ju Kim, Ji Yun Kim, Alireza G Senejani, Soo Seok Hwang, Lark Kyun Kim, Zuzana Tobiasova, Gap Ryol Lee, Joseph Craft, Alfred L M Bothwell, Je-Min Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99127 (2014)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor that regulates lipid and glucose metabolism. Although studies of PPARγ ligands have demonstrated its regulatory functions in inflammation and adaptive immunity, its
Externí odkaz:
https://doaj.org/article/ded578c19adc4d8ba998f3895c01a705
Autor:
Yongbo Liu, Jing Zhou, Xiaoyu Li, Xiaoting Zhang, Jintong Shi, Xuefei Wang, Hao Li, Shan Miao, Huifang Chen, Xiaoxiao He, Liting Dong, Gap Ryol Lee, Junke Zheng, Ru-Juan Liu, Bing Su, Youqiong Ye, Richard A. Flavell, Chengqi Yi, Yuzhang Wu, Hua-Bing Li
Publikováno v:
Nature Immunology. 23:1433-1444
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd57f0eaf09111df9422cf73160a7e79
https://doi.org/10.1038/s41590-022-01301-3
https://doi.org/10.1038/s41590-022-01301-3
Autor:
Gap Ryol Lee
Publikováno v:
Immune Network. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76b5ed54ed3b1ac7443508eb84282d8
https://doi.org/10.4110/in.2023.23.e4
https://doi.org/10.4110/in.2023.23.e4