Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gaoyuan Cao"'
Autor:
Mengyuan Kan, Maoyun Sun, Xiaofeng Jiang, Avantika R. Diwadkar, Vishal Parikh, Gaoyuan Cao, Eric Gebski, William Jester, Bo Lan, Reynold A. Panettieri, Cynthia Koziol-White, Quan Lu, Blanca E. Himes
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background CCAAT/Enhancer Binding Protein D (CEBPD), a pleiotropic glucocorticoid-responsive transcription factor, modulates inflammatory responses. Of relevance to asthma, expression of CEBPD in airway smooth muscle (ASM) increases with glu
Externí odkaz:
https://doaj.org/article/a5ddadf8bc3f433fb4bed68c1ebc7034
Autor:
Shengjie Xu, Anthony Schwab, Nikhil Karmacharya, Gaoyuan Cao, Joanna Woo, Nicholas Kim, Steven S. An, Reynold A. Panettieri Jr, Joseph A. Jude
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Activation of free fatty acid receptors (FFAR1 and FFAR4) which are G protein-coupled receptors (GPCRs) with established (patho)physiological roles in a variety of obesity-related disorders, induce human airway smooth muscle (HASM
Externí odkaz:
https://doaj.org/article/0d19388550394064a4134701d05d7fee
Autor:
Elena Chung, Christie A. Ojiaku, Gaoyuan Cao, Vishal Parikh, Brian Deeney, Shengjie Xu, Serena Wang, Reynold A. Panettieri, Cynthia Koziol-White
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Glucocorticoids (GCs) and β2-adrenergic receptor (β2AR) agonists improve asthma outcomes in most patients. GCs also modulate gene expression in human airway smooth muscle (HASM), thereby attenuating airway inflammation and airway hyperresp
Externí odkaz:
https://doaj.org/article/a64f01d636fe4849be42c39d562b0e16
Autor:
Manveen K Gupta, Kewal Asosingh, Mark Aronica, Suzy Comhair, Gaoyuan Cao, Serpil Erzurum, Reynold A Panettieri, Sathyamangla V Naga Prasad
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125803 (2015)
β2-adrenergic receptor (β2AR) agonists (β2-agonist) are the most commonly used therapy for acute relief in asthma, but chronic use of these bronchodilators paradoxically exacerbates airway hyper-responsiveness. Activation of βARs by β-agonist le
Externí odkaz:
https://doaj.org/article/042c0fc46acc4eedab5f06352cf1c857
Autor:
Shengjie Xu, Nikhil Karmacharya, Gaoyuan Cao, Changjiang Guo, Andrew Gow, Reynold A. Panettieri, Joseph A. Jude
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(3)
Obesity can aggravate asthma by enhancing airway hyperresponsiveness (AHR) and attenuating response to treatment. However, the precise mechanisms linking obesity and asthma remain unknown. Human airway smooth muscle (HASM) cells exhibit amplified exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709b8f09ce70e24d59286de7456f5af0
https://pubmed.ncbi.nlm.nih.gov/35787188
https://pubmed.ncbi.nlm.nih.gov/35787188
Autor:
Yuanyue Zhang, Jacob T. Bailey, En Xu, Kunal Singh, Marieke Lavaert, Verena M. Link, Shanti D’Souza, Alex Hafiz, Jian Cao, Gaoyuan Cao, Derek B. Sant’Angelo, Wei Sun, Yasmine Belkaid, Avinash Bhandoola, Dorian B. McGavern, Qi Yang
Publikováno v:
Nature Immunology. 23:1714-1725
Increasing evidence indicates close interaction between immune cells and the brain, revising the traditional view of the immune privilege of the brain. However, the specific mechanisms by which immune cells promote normal neural function are not enti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb960b8f0dcfe1aa321ed3f7246f414
https://doi.org/10.1038/s41590-022-01349-1
https://doi.org/10.1038/s41590-022-01349-1
Autor:
Brian T. Deeney, Gaoyuan Cao, Sarah Orfanos, Jordan Lee, Mengyuan Kan, Blanca E. Himes, Vishal Parikh, Cynthia J. Koziol-White, Steven S. An, Reynold A. Panettieri
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L142-L151
Epinephrine (EPI), an endogenous catecholamine involved in the body’s fight-or-flight responses to stress, activates α1-adrenergic receptors (α1ARs) expressed on various organs to evoke a wide range of physiological functions, including vasoconst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3ac31e32f02e0bf7b173fa9248f6b1f
https://doi.org/10.1152/ajplung.00444.2021
https://doi.org/10.1152/ajplung.00444.2021
Autor:
En Xu, Gaoyuan Cao, Zhi Yang, Yuanyue Zhang, Youwen Si, Kunal Singh, Joseph Jude, Steven S. An, Cynthia J. Koziol‐White, Reynold A. Panettieri, Qi Yang
Publikováno v:
Allergy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee26306b499b7aa9cb3450cc426f9f2
https://doi.org/10.1111/all.15766
https://doi.org/10.1111/all.15766
Autor:
Shengjie Xu, Nikhil Karmacharya, Joanna Woo, Gaoyuan Cao, Changjiang Guo, Andrew Gow, Reynold A. Panettieri, Joseph A. Jude
Publikováno v:
American journal of respiratory cell and molecular biology. 68(1)
Bronchomotor tone modulated by airway smooth muscle shortening represents a key mechanism that increases airway resistance in asthma. Altered glucose metabolism in inflammatory and airway structural cells is associated with asthma. Although these obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7e2b91e03aa8f2975267600fa2bd7d
https://pubmed.ncbi.nlm.nih.gov/36227725
https://pubmed.ncbi.nlm.nih.gov/36227725
Autor:
Ippolito, Michael, De Pascali, Francesco, Hopfinger, Nathan, Komolov, Konstantin E., Laurinavichyute, Daniela, Reddy, Poli Adi Narayana, Sakkal, Leon A., Rajkowski, Kyle Z., Nayak, Ajay P., Lee, Justin, Lee, Jordan, Gaoyuan Cao, Donover, Preston S., Reichman, Melvin, An, Steven S., Salvino, Joseph M., Penn, Raymond B., Armen, Roger S., Scott, Charles P., Benovic, Jeffrey L.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/1/2023, Vol. 120 Issue 31, p1-12, 54p