Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gaoyan, Kuang"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Osteoarthritis (OA) is a prevalent clinical condition affecting the entire joint, characterized by its multifactorial etiology and complex pathophysiology. The onset of OA is linked to inflammatory mediators produced by the synovium, cartilage, and s
Externí odkaz:
https://doaj.org/article/bf8e0690706943b898bfeca99a68846b
Autor:
Xiaotong Xu, Naping Li, Yongrong Wu, Ke Yan, Yilin Mi, Nanxing Yi, Xuyi Tan, Gaoyan Kuang, Min Lu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Knee osteoarthritis (KOA), a chronic degenerative disease, is mainly characterized by destruction of articular cartilage and inflammatory reactions. At present, there is a lack of economical and effective clinical treatment. Zhuifeng Toug
Externí odkaz:
https://doaj.org/article/b66c479b9e154eff9ca160d708881f2a
Autor:
Nanxing Yi, Yilin Mi, Xiaotong Xu, Naping Li, Fan Zeng, Ke Yan, Kaiyun Tan, Gaoyan Kuang, Min Lu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
As life expectancy increases, Osteoarthritis (OA) is becoming a more frequently seen chronic joint disease. The main characteristics of OA are loss of articular cartilage, subchondral bone sclerosis, and synovial inflammation. Baicalein (Bai), a trad
Externí odkaz:
https://doaj.org/article/8d2f7fb12ce547eb9c9346547d22e41a
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids, proteins, and metabolites. Exosomes transfer substances and informatio
Externí odkaz:
https://doaj.org/article/c92b50dc16ef439897eebb2a0ff5b49e
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Diabetic nephropathy (DN) is one of the main complications of diabetes and the main cause of diabetic end-stage renal disease, which is often fatal. DN is usually characterized by progressive renal interstitial fibrosis, which is closely related to t
Externí odkaz:
https://doaj.org/article/e2ab698b4a404ac2b3df5e21042012f0
Autor:
Yilin Mi, Nanxing Yi, Xiaotong Xu, Fan Zeng, Naping Li, Xuyi Tan, Zhixian Gong, Ke Yan, Gaoyan Kuang, Min Lu
Publikováno v:
Food & Function. 14:4065-4077
Prebiotics can delay the progression of PTOA by regulating the metabolites of gut microbiota and protecting the gut barrier, which gives a new perspective for the application of prebiotics to PTOA.
Publikováno v:
Computational and Mathematical Methods in Medicine. 2022:1-21
Background. Knee osteoarthritis (KOA) is a common degenerative joint disease. In this study, we aimed to identify new biomarkers of KOA to improve the accuracy of diagnosis and treatment. Methods. GSE98918 and GSE51588 were downloaded from the Gene E
Autor:
Nanxing Yi, Yilin Mi, Xiaotong Xu, Naping Li, Baiyi Chen, Ke Yan, Kaiyun Tan, Bo Zhang, Linhua Wang, Gaoyan Kuang, Min Lu
Publikováno v:
International immunopharmacology. 113
Osteoarthritis (OA) is a common degenerative disease with few treatments. In traditional Chinese medicine (TCM), Radix Angelicae biseratae (RAB) is commonly used to treat OA. Nodakenin (Nod) is one main coumarin active component in RAB and exhibits a
Publikováno v:
Journal of Cancer
Emerging evidence indicates that long noncoding RNAs (lncRNAs) are closely associated with colorectal cancer (CRC) tumorigenesis. One example is lncRNA Deleted in Lymphocytic Leukemia 2 (DLEU2). However, how DLEU2 contributes to CRC is still poorly u
Publikováno v:
Tropical Journal of Pharmaceutical Research. 19:1701-1708
Purpose: To determine the therapeutic effects of kidney yang-tonifying, blood-activating and phlegmeliminating methods on steroid-induced osteonecrosis of femoral head (SONFH), and their mechanisms of action.Methods: A rabbit model of SONFH was estab