Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gaoshang, Chai"'
Autor:
Haitao Yu, Mengzhu Li, Qihang Pan, Yanchao Liu, Yao Zhang, Ting He, Huisheng Yang, Yue Xiao, Ying Weng, Yang Gao, Dan Ke, Gaoshang Chai, Jian‐Zhi Wang
Publikováno v:
MedComm, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract Platelets may serve as a perfect peripheral source for exploring diagnostic biomarkers for Alzheimer's disease (AD); however, the molecular linkage between platelet and the brain is missing. To find the common altered and driving molecules i
Externí odkaz:
https://doaj.org/article/9245d0b608234789a2db308f78fec2ad
Autor:
Junjie Liang, Shanshan Han, Chao Ye, Haimeng Zhu, Jiajun Wu, Yunjuan Nie, Gaoshang Chai, Peng Zhao, Dengxin Zhang
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 512 (2023)
Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients. Sevoflurane, an inhaled anesthetic, has been demonstrated to be associated with POCD i
Externí odkaz:
https://doaj.org/article/3bfe9da2422d445dbddc415c44873963
Autor:
Yunjuan Nie, Kaikai Yu, Boyu Li, Yudong Hu, Hui Zhang, Ruiting Xin, Yue Xiong, Peng Zhao, Gaoshang Chai
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 4, Pp 377-384 (2019)
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease characterized by inflammation, multifocal fibrotic lesions and excessive collagen deposition with limited therapies. As a major bioactive compound in garlic, S-allyl-l-cyste
Externí odkaz:
https://doaj.org/article/ae32e74361554f1794bf7b4d4613d00b
Autor:
Peng Zhao, Xiaohang Qian, Yunjuan Nie, Na Sun, Zhongxuan Wang, Jiajun Wu, Chen Wei, Ruikun Ma, Zhe Wang, Gaoshang Chai, Yuqing Li
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) is a devastating disease in the elderly with no known effective treatment. It is characterized by progressive deterioration of memory and cognition. Many new potential targets are being investigated to develop effective the
Externí odkaz:
https://doaj.org/article/b4b95fd03e67469f98987b4e47a715f0
Autor:
Peng Zhao, Yaqian You, Zhe Wang, Yanjun Zhou, Gaoshang Chai, Gen Yan, Zhewu Jin, Qing Wang, Hongxu Sun
Publikováno v:
Brain Structure and Function. 227:1051-1065
Sleep disturbance is common in patients with Alzheimer’s disease (AD), and orexin A is a pivotal neurotransmitter for bidirectionally regulating the amyloid-β (Aβ) deposition of AD brain and poor sleep. In the present study, we examined the chara
Autor:
Yunjuan Nie, Xiaorun Zhai, Jiao Li, Aijuan Sun, Huilian Che, Christman, John W., Gaoshang Chai, Peng Zhao, Manjula Karpurapu
Publikováno v:
Aging & Disease; Aug2023, Vol. 14 Issue 4, p1441-1457, 17p
Autor:
Yunjuan Nie, Zhongxuan Wang, Gaoshang Chai, Yue Xiong, Boyu Li, Hui Zhang, Ruiting Xin, Xiaohang Qian, Zihan Tang, Jiajun Wu, Peng Zhao
Publikováno v:
Molecules, Vol 24, Iss 8, p 1510 (2019)
Acute lung injury (ALI) is a severe clinical disease marked by dysregulated inflammation response and has a high rate of morbidity and mortality. Macrophages, which play diverse roles in the inflammatory response, are becoming therapeutic targets in
Externí odkaz:
https://doaj.org/article/6f8fcdfc8dc34b9d847de3330606815a
Autor:
Manjula Karpurapu, Peng Zhao, Gaoshang Chai, John W Christman, Huilian Che, Aijuan Sun, Jiao Li, Xiaorun Zhai, Yunjuan Nie
Publikováno v:
Aging and disease.
Autor:
Gaoshang Chai, Jiajun Wu, Rongfei Fang, Yanlin Liu, Xuechun Wang, Xi Wang, Jinming Zhang, Jiali Zhou, Zhiqian Jiang, Haiyan Yi, Yunjuan Nie, Peng Zhao, Dengxin Zhang
Publikováno v:
SSRN Electronic Journal.
Autor:
Gaoshang Chai, Peng Zhao, Xiaohang Qian, Dan Zhang, Huilian Che, Yang Zhang, Yaqian You, Zhe Wu Jin, Xue Wang, Boyu Li, Yunjuan Nie
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 46:575-586
It has been established that lanatoside C, a FDA-approved cardiac glycoside, reduces proliferation of cancer cell lines. The proliferation of fibroblasts is critical to the pathogenesis of pulmonary fibrosis (PF), a progressive and fatal fibrotic lun