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Akademický článek

Ferroptosis-inducing nanomedicine and targeted short peptide for synergistic treatment of hepatocellular carcinoma

Autor: Luyang Wang, Le Tong, Zecheng Xiong, Yi Chen, Ping Zhang, Yan Gao, Jing Liu, Lei Yang, Chunqi Huang, Gaoqi Ye, Jing Du, Huibiao Liu, Wei Yang, Ying Wang

Publikováno v: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)

Abstract The poor prognosis of hepatocellular carcinoma (HCC) is still an urgent challenge to be solved worldwide. Hence, assembling drugs and targeted short peptides together to construct a novel medicine delivery strategy is crucial for targeted an

Externí odkaz: https://doaj.org/article/4791f7f01a5048198984deb59e2dea5f

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Akademický článek

Wheat alkylresorcinols modulate high-fat diet induced hepatic steatosis and insulin resistance through activating AMPK signaling pathway

Autor: Zongwei Wang, Lina Guan, Yiman Zhang, Xinyu Hou, Ziyuan Wang, Fei Gao, Gaoqi Ye, Jing Wang, Jie Liu

Publikováno v: Journal of Functional Foods, Vol 117, Iss , Pp 106238- (2024)

Wheat alkylresorcinols (ARs) are phenolic lipids present in the bran part of whole grain wheat, which have been proven to improve obesity and atherosclerosis. However, the effects of ARs on hepatic steatosis and their possible mechanisms remain uncle

Externí odkaz: https://doaj.org/article/d729ea01209d47c8a238244eef3b09a7

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Akademický článek

CD146 is a Novel ANGPTL2 Receptor that Promotes Obesity by Manipulating Lipid Metabolism and Energy Expenditure

Publikováno v: Advanced Science, Vol 8, Iss 6, Pp n/a-n/a (2021)

Abstract Obesity and its related complications pose an increasing threat to human health; however, targetable obesity‐related membrane receptors are not yet elucidated. Here, the membrane receptor CD146 is demonstrated to play an essential role in

Externí odkaz: https://doaj.org/article/2d60f8b3ecd04e4e80af82ab213691b8

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Akademický článek

miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis

Autor: Lihua Wang, Ergang Wang, Yi Wang, Robert Mines, Kun Xiang, Zhiguo Sun, Gaiting Zhou, Kai-Yuan Chen, Nikolai Rakhilin, Shanshan Chao, Gaoqi Ye, Zhenzhen Wu, Huiwen Yan, Hong Shen, Jeffrey Everitt, Pengcheng Bu, Xiling Shen

Publikováno v: eLife, Vol 7 (2018)

Inflammation often induces regeneration to repair the tissue damage. However, chronic inflammation can transform temporary hyperplasia into a fertile ground for tumorigenesis. Here, we demonstrate that the microRNA miR-34a acts as a central safeguard

Externí odkaz: https://doaj.org/article/22e0fc37293c4969b8b6caaf3ed6ada3

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5-Heptadecylresorcinol alleviated high-fat diet induced obesity and insulin resistance by activating brown adipose tissue

Autor: Zihui Yang, Siqi Yang, Ziyuan Wang, Yiming Hao, Zongwei Wang, Yulong Wei, Gaoqi Ye, Jie Liu, Jing Wang

Publikováno v: Food & Function.

5-Heptadecylresorcinol (AR-C17) improved the metabolism and energy expenditure of BAT, exhibiting a protective effect on obesity and insulin resistance in high-fat fed obese mice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a561a17da4d26ab3dafee9f932c1915f
https://doi.org/10.1039/d3fo00071k

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