Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gaopeng Guan"'
Autor:
Zheling Li, Xiaohui Qiu, Gaopeng Guan, Ke Shi, Shuyue Chen, Jiangjie Tang, Muzhang Xiao, Shijie Tang, Yu Yan, Jianda Zhou, Huiqing Xie
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30022- (2024)
Background: Wound healing is a complex biological process that can be impaired in individuals with diabetes. Diabetic wounds are a serious complication of diabetes that require promoting diagnosis and effective treatment. FGF-21, a member of the endo
Externí odkaz:
https://doaj.org/article/7627dcffcb224b189a052e55e18b4717
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Long-term/high-dose glucocorticoid (GC) use results in glycolipid metabolism disorder, which severely limits its clinical application. The role of the gut microbiota and its metabolites in GC-induced glycolipid metabolism disorder remains un
Externí odkaz:
https://doaj.org/article/28084cda474d4e3384273eaf2d775d28
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100188- (2022)
Chronic wounds caused by severe trauma remain a serious challenge for clinical treatment. In this study, we developed a novel angiogenic 3D-bioprinted peptide patch to improve skin wound healing. The 3D-bioprinted technology can fabricate individual
Externí odkaz:
https://doaj.org/article/1bb81a06a40d4ca7a42c4d88454d1156
Publikováno v:
The World Journal of Men's Health, Vol 37, Iss 2, Pp 186-198 (2019)
Purpose: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secre-tion in mouse Leydig cells.Materials and Methods: Mouse testis of different postnatal stages was isolated to detect the ex
Externí odkaz:
https://doaj.org/article/1604851177244100a121f96164a63880
Publikováno v:
Hormone and Metabolic Research. 55:136-141
KLF11 regulates insulin gene expression through binding to the insulin promoter and has been reported as a causative gene for maturity-onset diabetes of the young 7 (MODY7). Here, we report a novel KLF11 variant associated with a three-generation fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2495d2a9bc5dbf99dc81d5c98ae8f256
https://doi.org/10.1055/a-1961-6281
https://doi.org/10.1055/a-1961-6281
Publikováno v:
Small. 18:2203064
Diabetic wound is one of the common complications in diabetic patients, which exhibits chronic, hard-to-heal characteristics. The healing process of wounds is impaired by several factors, including excessive oxidative stress, blocked angiogenesis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84da660005325ce431dc11aed6a4075f
https://doi.org/10.1002/smll.202203064
https://doi.org/10.1002/smll.202203064
Autor:
Shengyuan Liu, Wenyin Huang, Huan Yu, Jun Zhang, Xiang Gu, Pu-Hua Zhang, Gaopeng Guan, Lei Yang
Publikováno v:
Molecular Medicine Reports
Endoplasmic reticulum (ER) stress and autophagy are involved in myocardial ischemia‑reperfusion (I/R) injury; however, their roles in this type of injury remain unclear. The present study investigated the roles of ER stress and autophagy, and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ce305524e10c22bd4d7c9713734144
http://europepmc.org/articles/PMC6580049
http://europepmc.org/articles/PMC6580049
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 392:715-722
Endoplasmic reticulum (ER) stress-induced apoptosis is a major cause of myocardial ischemia/reperfusion (I/R) injury. Emerging evidence indicates that glucagon-like peptide-1 (GLP-1) has potential cardioprotective effects. However, the precise mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4303fd7ad73c6147223ae91e1ce4923
https://doi.org/10.1007/s00210-019-01625-2
https://doi.org/10.1007/s00210-019-01625-2
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Objectives. We aimed to determine the effects of curcumin on palmitic acid- (PA-) induced human osteoblast-like Saos-2 cell apoptosis and to explore the potential molecular mechanisms in vitro level. Methods. Saos-2 cell were cultured with PA with or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79da08a4c2d191d5247141c81728a7d0
Autor:
Lanjie Lei, Shengyuan Liu, Lei Yang, Gaopeng Guan, Xiang Gu, Zhenzhen Jiang, Qizhuang Lv, Xiuwen Zhan
Publikováno v:
Cell Stress and Chaperones. 23:1283-1294
Palmitic acid (PA) is the most common saturated long-chain fatty acid in food that causes cell apoptosis. However, little is known about the molecular mechanisms of PA toxicity. In this study, we explore the effects of PA on proliferation and apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c116a9b3de8fd639eb4a145aba2ae6
https://doi.org/10.1007/s12192-018-0936-8
https://doi.org/10.1007/s12192-018-0936-8