Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Gaojun Wu"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background In this study, we examine the association between the hyperuricemia(HU) and hypertension(HTN) in Chinese young adults. Besides, the correlation between the occurrence of thickened left ventricular wall and HU was identified in pat
Externí odkaz:
https://doaj.org/article/308d2ddc185c4d569ac8c4cde914dbbb
Autor:
Ying Zhao, Shijie Fan, Hong Zhu, Qingqing Zhao, Zimin Fang, Diyun Xu, Wante Lin, Liming Lin, Xiang Hu, Gaojun Wu, Julian Min, Guang Liang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Recent studies have shown the crucial role of podocyte injury in the development of diabetic kidney disease (DKD). Deubiquitinating modification of proteins is widely involved in the occurrence and development of diseases. Here, we explore t
Externí odkaz:
https://doaj.org/article/19222389563c4e27af0dbca23196de8b
Autor:
Xiong Chen, Jinfu Qian, Shiqi Liang, Jianchang Qian, Wu Luo, Yujuan Shi, Hong Zhu, Xiang Hu, Gaojun Wu, Xiaokun Li, Guang Liang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1693-1710 (2024)
Protein tyrosine kinases (RTKs) modulate a wide range of pathophysiological events in several non-malignant disorders, including diabetic complications. To find new targets driving the development of diabetic cardiomyopathy (DCM), we profiled an RTKs
Externí odkaz:
https://doaj.org/article/6c14b6a9fb5e4523a1c83f658d7fa81a
Autor:
Jinfu Qian, Qinyan Wang, Jiachen Xu, Shiqi Liang, Qingsong Zheng, Xiaocheng Guo, Wu Luo, Weijian Huang, Xiaohong Long, Julian Min, Yi Wang, Gaojun Wu, Guang Liang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Abstract Background Chronic inflammation contributes to the progression of isoproterenol (ISO)‐induced heart failure (HF). Caspase‐associated recruitment domain (CARD) families are crucial proteins for initiation of inflammation in innate immunit
Externí odkaz:
https://doaj.org/article/66fdcc9941db4b60a02b485ff6e3fd6b
Autor:
Minxiu Wang, Qianhui Zhang, Shuaijie Lou, Leiming Jin, Gaojun Wu, Wenqi Wu, Qidong Tang, Yi Wang, Xiaohong Long, Ping Huang, Wu Luo, Guang Liang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115660- (2023)
Diabetic kidney disease (DKD) is one of the severe complications of diabetes mellitus-related microvascular lesions, which remains the leading cause of end-stage kidney disease. The genesis and development of DKD is closely related to inflammation. M
Externí odkaz:
https://doaj.org/article/721f6bba648f49838d9606b58ef6a922
Autor:
Zhuqi Huang, Sirui Shen, Xue Han, Weixin Li, Wu Luo, Liming Lin, Mingjiang Xu, Yi Wang, Weijian Huang, Gaojun Wu, Guang Liang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-15 (2023)
Abstract Atherosclerosis is a chronic inflammatory disease with high morbidity and mortality rates worldwide. Doublecortin‐like kinase 1 (DCLK1), a microtubule‐associated protein kinase, is involved in neurogenesis and human cancers. However, the
Externí odkaz:
https://doaj.org/article/77588e6d0d2c4f83a5fb111b485a11b3
Autor:
Tingting Yuan, Honglin Tang, Xiaojie Xu, Jingjing Shao, Gaojun Wu, Young-Chang Cho, Yuan Ping, Guang Liang
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107251- (2023)
Externí odkaz:
https://doaj.org/article/7900afceac8047fc9801a283ef2290a3
Autor:
Zimin Fang, Gaojun Wu, Jian Sheng, Bozhi Ye, Zhouqing Huang, Jianjiang Xu, Jianqin Zhang, Jibo Han, Bingjiang Han, Jiajun Xu
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16619- (2023)
Vascular smooth muscle cells (VSMCs) are primarily responsible for vasoconstriction and the regulation of blood pressure1. Pyroptosis, a particular form of regulated cell death, is involved in multiple vascular injuries, including hypertensive vascul
Externí odkaz:
https://doaj.org/article/17a744035b594b2195d295204217115f
Autor:
Wu Luo, Ke Lin, Junyi Hua, Jibo Han, Qiuyan Zhang, Lingfeng Chen, Zia A. Khan, Gaojun Wu, Yi Wang, Guang Liang
Publikováno v:
Advanced Science, Vol 9, Iss 31, Pp n/a-n/a (2022)
Abstract Diabetes manifests as chronic inflammation and leads to the development diabetic cardiomyopathy (DCM). Targeting key proteins in inflammatory signaling may provide new therapy for DCM. In this study, the authors explore the pharmacological e
Externí odkaz:
https://doaj.org/article/c1c7750e56114b77a9290ad9d1c5ba39
Autor:
Xiaodong Zhou, Ruiyu Shi, Gaojun Wu, Qianli Zhu, Changzuan Zhou, Liangguo Wang, Chenglong Xue, Yuanyuan Jiang, Xueli Cai, Weijian Huang, Peiren Shan
Publikováno v:
ESC Heart Failure, Vol 8, Iss 2, Pp 1284-1294 (2021)
Abstract Aims This study aimed to determine prevalence, predictors, and association with ischaemic stroke risk of spontaneous echocardiographic contrast (SEC) or left ventricular thrombus (LVT) in patients with heart failure with reduced ejection fra
Externí odkaz:
https://doaj.org/article/f79defcb94954448a1bcb6b3db00218a