Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gaohua Yang"'
Autor:
Pengjie Yang, Jinzhong Tian, Lu Zhang, Hui Zhang, Gaohua Yang, Yimeng Ren, Jingyuan Fang, Yang Gu, Weihong Jiang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 1, Pp 43-54 (2024)
Gut microbes are closely related with human health, but remain much to learn. Clostridium symbiosum is a conditionally pathogenic human gut bacterium and regarded as a potential biomarker for early diagnosis of intestinal tumors. However, the absence
Externí odkaz:
https://doaj.org/article/f2acde9e8ed441268fb2b545fbfc58ce
Autor:
Jinci Yan, Chengli Fang, Gaohua Yang, Jianxu Li, Yanqiang Liu, Lu Zhang, Pengjie Yang, Jingyuan Fang, Yang Gu, Yu Zhang, Weihong Jiang
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Berberine (BBR) is a commonly used anti-intestinal inflammation drug, and its anti-cancer activity has been found recently. BBR can intervene and control malignant colorectal cancer (CRC) through intestinal microbes, but the direc
Externí odkaz:
https://doaj.org/article/9a83a7854e6b4c9ca86918aecf56ec71
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune severity index (SII), and prognostic nutritional index (PNI) are associated with the prognosis of gastric, lung, and breast cancers. However, the predictive
Externí odkaz:
https://doaj.org/article/d343717fb62b415f8e9008400e30b464
Autor:
Gaohua Yang, Sen Hong, Pengjie Yang, Yuwei Sun, Yong Wang, Peng Zhang, Weihong Jiang, Yang Gu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Flavonoids are abundant polyphenols in plants but it is not well understood how their metabolism is initiated by microbes in the human gut. Here, the authors identify and characterise an ene-reductase from the gut bacterium, Flavonifractor plautii AT
Externí odkaz:
https://doaj.org/article/20b0c36a9d084476a6121df172d0f507
Publikováno v:
Experimental and Therapeutic Medicine. 23
The expression profile and role of yes-associated protein (YAP) in occurrence and development of breast cancer is ambiguous. The present study aimed to explore the relationship among the YAP, β-catenin and smoothened (SMO) signaling pathways to prov
Publikováno v:
Nucleic Acids Research
Quorum-sensing (QS) mediated dynamic regulation has emerged as an effective strategy for optimizing product titers in microbes. However, these QS-based circuits are often created on heterologous systems and require careful tuning via a tedious testin
Background: The mechanism of the Yes-associated protein in the occurrence and development of breast cancer is still unclear. Here, we aimed to explore the relationship among the Yes-associated protein, β-catenin, and Smoothened signaling pathways to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c03d5c6d57581e0ddcaa56a35d70007c
https://doi.org/10.21203/rs.3.rs-1010969/v1
https://doi.org/10.21203/rs.3.rs-1010969/v1
Autor:
Pengjie Yang, Sen Hong, Peng Zhang, Gaohua Yang, Yang Gu, Sun Yuwei, Weihong Jiang, Yong Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Gut microbial transformations of flavonoids, an enormous class of polyphenolic compounds abundant in plant-based diets, are closely associated with human health. However, the enzymes that initiate the gut microbial metabolism of flavones and flavonol
Dynamic regulation has emerged as an effective strategy to improve product titers by balancing metabolic networks, which can be implemented by coupling gene expression to pathway-independent regulatory elements, such as quorum-sensing (QS) systems. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc962fb6d76d3fb0737775b3648835d
Publikováno v:
Metabolic Engineering. 35:121-128
An efficient production process is important for industrial microorganisms. The cellular efficiency of solventogenic clostridia, a group of anaerobes capable of producing a wealth of bulk chemicals and biofuels, must be improved for competitive comme