Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gaofei Wei,"'
Autor:
Renming Fan, Ruizhuo Lin, Shuo Zhang, Aohua Deng, Yongrui Hai, Junyan Zhuang, Yang Liu, Maosheng Cheng, Gaofei Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1742-1758 (2024)
Mitochondrial membrane remodeling can trigger the release of mitochondrial DNA (mtDNA), leading to the activation of cellular oxidative stress and immune responses. While the role of mitochondrial membrane remodeling in promoting inflammation in hepa
Externí odkaz:
https://doaj.org/article/2246674c496b4cbdaf7c70db58d65f07
Autor:
Renming Fan, Aohua Deng, Ruizhuo Lin, Shuo Zhang, Caiyan Cheng, Junyan Zhuang, Yongrui Hai, Minggao Zhao, Le Yang, Gaofei Wei
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Ferroptosis is an iron‐dependent cell death form that initiates lipid peroxidation (LPO) in tumors. In recent years, there has been growing interest on ferroptosis, but how to propel it forward translational medicine remains in mist. Altho
Externí odkaz:
https://doaj.org/article/1f72fe9e26cf4b11a50c98ddb6416e36
Autor:
Yongrui Hai, Renming Fan, Ting Zhao, Ruizhuo Lin, Junyan Zhuang, Aohua Deng, Shanshui Meng, Zhuang Hou, Gaofei Wei
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107115- (2024)
Dihydroorotate dehydrogenase (DHODH)-mediated ferroptosis defense is a targetable vulnerability in cancer. Currently, only a few DHODH inhibitors have been utilized in clinical practice. To further enhance DHODH targeting, we introduced the mitochond
Externí odkaz:
https://doaj.org/article/0f0a8868cb46407fb20e10e039054461
Autor:
Wei Wang, Tingting Pan, Rui Su, Mingbin Chen, Wandi Xiong, Congjun Xu, Ling Huang, Wenbao Wang, Yunlei Hou, Zhenghui Kang, Gaofei Wei,
Publikováno v:
Frontiers in Chemistry; 2024, p01-11, 11p
Autor:
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Maosheng Cheng, Gaofei Wei
Publikováno v:
Journal of Medicinal Chemistry. 66:875-889
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ebb6597f7304249d8698ca0c8175ab
https://doi.org/10.1021/acs.jmedchem.2c01719
https://doi.org/10.1021/acs.jmedchem.2c01719
Publikováno v:
CCS Chemistry. 3:2245-2258
A highly efficient and chemoselective dual functionalization of unprotected phenols with α- or β-hydroxyl acids is presented. A variety of valuable benzofuranones and dihydrocoumarins are delivered...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d769dffa31e5fe030861ecb4d280958
https://doi.org/10.31635/ccschem.020.202000404
https://doi.org/10.31635/ccschem.020.202000404
Publikováno v:
International Journal of Electrochemical Science. 18:100057
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbab3fefb08bd0957fad226d8caeed0
https://doi.org/10.1016/j.ijoes.2023.100057
https://doi.org/10.1016/j.ijoes.2023.100057
Autor:
Yifeng Shen, Congjun Xu, Yanjuan Huang, Zeqian Huang, Zishan Zeng, Liangfeng Huang, Gaofei Wei, Xiaoqi Sun, Chunshun Zhao
Publikováno v:
Theranostics
Cancer metastases is still a hurdle for good prognosis and live quality of breast cancer patients. Treatment strategies that can inhibit metastatic cancer while treating primary cancer are needed to improve the therapeutic effect of breast cancer. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae385531e2df673e099134a64724d0e
http://europepmc.org/articles/PMC6735384
http://europepmc.org/articles/PMC6735384
Autor:
Chunshun Zhao, Yali Jiang, Yifeng Shen, Yanjuan Huang, Xiaoqi Sun, Gaofei Wei, Zeqian Huang, Liangfeng Huang
Publikováno v:
European Journal of Medicinal Chemistry. 169:53-64
The therapeutic efficacy of targeted therapy is dramatically hindered by multidrug resistance (MDR) because of elevated GSH levels. Thus, depletion of intracellular GSH level is highly desirable for targeted-therapeutic agents to reverse tumor drug r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744a3aefcbc79663fe6814d246a850f6
https://doi.org/10.1016/j.ejmech.2019.02.065
https://doi.org/10.1016/j.ejmech.2019.02.065
Publikováno v:
2021 IEEE 4th International Conference on Electronics Technology (ICET).
To calculate the burning surface of the dual burning rate star grain in a more efficient and generalized way, a bidirectional coupled SRM performance prediction method, which combined with the burnback simulation and the internal ballistics calculati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c59f460aca085bc74e25e4b6e66f2063
https://doi.org/10.1109/icet51757.2021.9451031
https://doi.org/10.1109/icet51757.2021.9451031