Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Gaochao, Zhou"'
Autor:
Gaochao Zhou, Bo Zhu, Junming Zhao, Guanghao Zhu, Biaobing Jin, Yijun Feng, Lin Kang, Weiwei Xu, Jian Chen, Peiheng Wu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract We propose and demonstrate a type of a broadband half-wave plate that operates in the reflective mode. It consists of a metal grating embedded in a dielectric slab and placed on top of a grounded metal surface. We theoretically show that owi
Externí odkaz:
https://doaj.org/article/fee4e736e17f4ce4b4de829065a3a25d
Autor:
Thomas W. Rosahl, Jin Cao, Kithsiri Herath, Ku Lu, Guillaume Pavlovic, Gaochao Zhou, Taro E. Akiyama, Corin O. Miller, Cai Li, Xiaodong Yang, Roger Askew
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E386-E393
Fructose consumption in humans and animals has been linked to enhanced de novo lipogenesis, dyslipidemia, and insulin resistance. Hereditary deficiency of ketohexokinase (KHK), the first enzymatic step in fructose metabolism, leads to essential fruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5919e13d4211b01af9fbec4c5834b6
https://doi.org/10.1152/ajpendo.00027.2018
https://doi.org/10.1152/ajpendo.00027.2018
Autor:
F. Anthony Romero, Robert W. Myers, Hong-Ping Guan, Anantha Gollapudi, Gaochao Zhou, Ku Lu, James F. Dropinski, Marc M. Kurtz, Xiaodong Yang, Cai Li, Iyassu K. Sebhat, Tesfaye Biftu, Danqing Feng, Ahmet Kekec, Ann E. Weber, Qing Shao, Daniel M. Kemp, Andrew Kassick, Shiyao Xu, Maria E. Trujillo
Publikováno v:
ACS Medicinal Chemistry Letters. 9:39-44
5'-Adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of mammalian energy homeostasis and has been implicated in mediating many of the beneficial effects of exercise and weight loss including lipid and glucose trafficking. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523ed2d42da00835ac297ba9e01c4ffe
https://doi.org/10.1021/acsmedchemlett.7b00417
https://doi.org/10.1021/acsmedchemlett.7b00417
Autor:
Joe Clemas, Jerry Andrew Taylor, Feroze Ujjainwalla, Jim Tata, Doris F. Cully, Tom Wisniewski, Wei Tang, Charlene Bopp, Clare London, Andreas Verras, Scott B. Hoyt, Andrea Sok, Elaine Tung, Douglas J. MacNeil, Gaochao Zhou, Amjad Ali, Qing Chen, Gino Salituro, Yusheng Xiong, Daniel R. McMasters, Mary Struthers, Ning Ren, Ruth A. Duffy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2384-2388
We report the discovery and hit-to-lead optimization of a structurally novel indazole series of CYP11B2 inhibitors. Benchmark compound 34 from this series displays potent inhibition of CYP11B2, high selectivity versus related steroidal and hepatic CY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f9a114775b2eff2c4ce3ec96aa4668
https://doi.org/10.1016/j.bmcl.2017.04.021
https://doi.org/10.1016/j.bmcl.2017.04.021
Publikováno v:
2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz).
Recently, with the development of artificial electromagnetic medium, metamaterials offer people the ability to subjectively control electromagnetic wave and provide a promising solution for scarce terahertz (THz) functional devices. In this paper, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11404d1379b8c2bdc9c66c9a45682056
https://doi.org/10.1109/irmmw-thz.2019.8874219
https://doi.org/10.1109/irmmw-thz.2019.8874219
Autor:
Yahua Tang, Jian Chen, Jiaguang Han, Qi-Ye Wen, Peiheng Wu, Gaochao Zhou, Caihong Zhang, Shaoxian Li, Biaobing Jin, Jingbo Wu
Publikováno v:
Physical Review Applied. 11
This article describes the active control of terahertz waves using hybrid metamaterials containing embedded vanadium dioxide. VO${}_{2}$ undergoes an insulator-metal phase transition at around 68 \ifmmode^\circ\else\textdegree\fi{}C, causing its cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b978033005a50c74ca3842d2fcc001
https://doi.org/10.1103/physrevapplied.11.054016
https://doi.org/10.1103/physrevapplied.11.054016
Autor:
Chris J. van Koppen, Scott B. Hoyt, Gino Salituro, Elaine Tung, Jim Tata, Joe Clemas, Mark Rosenbach, Jack Gibson, Daphne Szeto, Wei Tang, Andreas Verras, Lee-Yuh Pai, Ning Ren, Carrie Ann Maxwell, Joe Metzger, Jose Castro-Perez, Qing Chen, Lina Yin, Daniel R. McMasters, Yusheng Xiong, Rolf W. Hartmann, Mary Struthers, Gui-Bai Liang, Charlene Bopp, Xiuying Ma, Gaochao Zhou, Richard Hajdu, Tom Wisniewski, Mike E. Lassman, Nicole Buist, Clare London, Andrea Sok, Gail Forrest, Sloan Stribling, Theresa McLaughlin, Qingzhong Hu, Tian-Quan Cai, Whitney Lane Petrilli
Publikováno v:
ACS Medicinal Chemistry Letters. 6:861-865
Hit-to-lead efforts resulted in the discovery of compound 19, a potent CYP11B2 inhibitor that displays high selectivity vs related CYPs, good pharmacokinetic properties in rat and rhesus, and lead-like physical properties. In a rhesus pharmacodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e60459ea9849aaebdf1fc299badb367
https://doi.org/10.1021/acsmedchemlett.5b00048
https://doi.org/10.1021/acsmedchemlett.5b00048
Autor:
Junming Zhao, Gaochao Zhou, Biaobing Jin, Weiwei Xu, Lin Kang, Peiheng Wu, Bo Zhu, Jian Chen, Guanghao Zhu, Yijun Feng
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
We propose and demonstrate a type of a broadband half-wave plate that operates in the reflective mode. It consists of a metal grating embedded in a dielectric slab and placed on top of a grounded metal surface. We theoretically show that owing to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f686dc8f5e7838179a6ff4b3f7da73fe
https://doi.org/10.1038/s41598-017-09561-y
https://doi.org/10.1038/s41598-017-09561-y
Autor:
Gaochao, Zhou, Penghui, Dai, Jingbo, Wu, Biaobing, Jin, Qiye, Wen, Guanghao, Zhu, Ze, Shen, Caihong, Zhang, Lin, Kang, Weiwei, Xu, Jian, Chen, Peiheng, Wu
Publikováno v:
Optics express. 25(15)
An active vanadium dioxide integrated metasurface offering broadband transmitted terahertz wave modulation with large modulation-depth under electrical control is demonstrated. The device consists of metal bias-lines arranged with grid-structure patt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb328b9de341b5d849a42848a868e7b5
https://pubmed.ncbi.nlm.nih.gov/28789224
https://pubmed.ncbi.nlm.nih.gov/28789224
Publikováno v:
Science China Information Sciences. 57:1-8
In this work we establish an equivalent circuit model to analyze the resonace of the metamaterial considering the loss of the unit cell and coupling effect between them. From this model, we find that metamaterial can be divided into three categories:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac0a625ae282c224e887d46f472b1d0
https://doi.org/10.1007/s11432-014-5184-7
https://doi.org/10.1007/s11432-014-5184-7