Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gaochao, Lv"'
Autor:
Yinfei Chen, Shiyu Zhu, Jiayu Fu, Jianguo Lin, Yan Sun, Gaochao Lv, Minhao Xie, Tao Xu, Ling Qiu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 12, Iss 6, Pp 869-878 (2022)
Despite advances in immunotherapy for the treatment of cancers, not all patients can benefit from programmed cell death ligand 1 (PD-L1) immune checkpoint blockade therapy. Anti-PD-L1 therapeutic effects reportedly correlate with the PD-L1 expression
Externí odkaz:
https://doaj.org/article/973b9fbccc764f1aa05203155e8d8c55
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 213 (2023)
Immunotherapy blocking programmed cell death protein 1/programmed death ligand 1 (PD-1/PD-L1) pathway has achieved great therapeutic effect in the clinic, but the overall response rate is not satisfactory. Early studies showed that response to treatm
Externí odkaz:
https://doaj.org/article/a0be3c1591cf4b19b8a961440ae33b23
Autor:
Jianguo Lin, Dingyao Gao, Shijie Wang, Gaochao Lv, Xiuting Wang, Chunmei Lu, Ying Peng, Ling Qiu
Publikováno v:
Journal of the American Chemical Society. 144:7667-7675
Publikováno v:
Cancer Immunology, Immunotherapy. 70:1721-1733
The checkpoint blockade immunotherapy has become a potent treatment strategy for cancers, and programmed death ligand-1 (PD-L1) is a prominent checkpoint ligand that is highly expressed in some cancers. The identification of immune checkpoint marker
Publikováno v:
Nuclear Medicine and Biology. :72-79
Introduction Peptide analogues have attracted considerable attention in the field of developing novel positron emission tomography (PET) imaging agents due to their unique properties. Nevertheless, the complicated radiolabeling process and fast metab
Autor:
Ling Qiu, Yann Seimbille, Jianguo Lin, Gaochao Lv, Ke Li, Ying Peng, Qingzhu Liu, Minhao Xie, Xi Li
Publikováno v:
Analytical Chemistry, 92(17), 11627-11634. American Chemical Society
Overexpression of legumain is closely associated with tumor proliferation, invasion, and metastasis. Because of its intrinsic properties, such as high sensitivity and resolution, positron emission tomography (PET) has become an effective imaging tech
Autor:
Jianguo Lin, Dingyao Gao, Shijie Wang, Gaochao Lv, Xiuting Wang, Chunmei Lu, Ying Peng, Ling Qiu
Publikováno v:
Journal of the American Chemical Society. 145:748-748
Autor:
Gaochao, Lv, Yinxing, Miao, Yinfei, Chen, Chunmei, Lu, Xiuting, Wang, Minhao, Xie, Ling, Qiu, Jianguo, Lin
Publikováno v:
Bioorganic chemistry. 115
Programmed death ligand 1 (PD-L1) expression level is a reproducible biomarker for guiding stratification of patients to immunotherapy. However, the most widely used immunohistochemistry method is incompetent to fully understand the PD-L1 expression
Publikováno v:
New Journal of Chemistry. 43:3419-3427
A new hybrid metallic prodrug Te–S–S–NHC–Ru (Te–S–S–NHC: 17-α-[1,3-bis(4-(tert-butyl)benzyl)-4-methyl-2,3-dihydro-1H-imidazole-bis(2-diethylcarbonate)disulfide-1H-1,2,3-triazol-1-yl]-19-testosterone) was designed and synthesized by a t
Autor:
Ke Li, Yann Seimbille, Ying Peng, Qingzhu Liu, Jianguo Lin, Gaochao Lv, Minhao Xie, Ling Qiu, Feng Gao, Wei Wang
Publikováno v:
Theranostics, 9(23), 6962-6975. Ivyspring International Publisher
Theranostics
Theranostics
Purpose: Positron emission tomography (PET) imaging of apoptosis is very important for early evaluation of tumor therapeutic efficacy. A stimuli-responsive probe based on the peptide sequence Asp-Glu-Val-Asp (DEVD), [18F]DEVD-Cys(StBu)-PPG(CBT)-AmBF3