Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Gao Sun"'
Autor:
Helle Keinicke, Gao Sun, Caroline M Junker Mentzel, Merete Fredholm, Linu Mary John, Birgitte Andersen, Kirsten Raun, Marina Kjaergaard
Publikováno v:
Endocrine Connections, Vol 9, Iss 8, Pp 755-768 (2020)
The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased dramatically worldwide and, subsequently, also the risk of developing non-alcoholic steatohepatitis (NASH), hepatic fibrosis, cirrhosis and cancer. Today, weight lo ss is the o
Externí odkaz:
https://doaj.org/article/e68e13f481f74afe897403913b097076
Autor:
Gao Sun, Charles V. Jackson, Karen Zimmerman, Li-Kun Zhang, Courtney M. Finnearty, George E. Sandusky, Guodong Zhang, Richard G. Peterson, Yi-Xin (Jim) Wang
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH). Dietary rodent models employ high fat,
Externí odkaz:
https://doaj.org/article/94d47ec6dd364d2985b6a79a72c89c6a
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Background Managing infertility patients with poor ovarian response (POR) to ovarian stimulation remains unmet clinically. Besides economic burdens, patients with POR have a poor prognosis during in vitro fertilization and embryo transfer (I
Externí odkaz:
https://doaj.org/article/2a4dbf935c2e401bb4c0feb5ce43a584
Autor:
Gao Sun, Gabriela da Silva Xavier, Tracy Gorman, Claire Priest, Antonia Solomou, David J. Hodson, Marc Foretz, Benoit Viollet, Pedro-Luis Herrera, Helen Parker, Frank Reimann, Fiona M. Gribble, Stephanie Migrenne, Christophe Magnan, Anna Marley, Guy A. Rutter
Publikováno v:
Molecular Metabolism, Vol 4, Iss 4, Pp 277-286 (2015)
Aims/Hypothesis: Glucagon release from pancreatic alpha cells is required for normal glucose homoeostasis and is dysregulated in both Type 1 and Type 2 diabetes. The tumour suppressor LKB1 (STK11) and the downstream kinase AMP-activated protein kinas
Externí odkaz:
https://doaj.org/article/4f54fb1ea32f4d228578aa597d3cc524
Autor:
Sagen Zac-Varghese, Stefan Trapp, Paul Richards, Sophie Sayers, Gao Sun, Stephen R. Bloom, Frank Reimann, Fiona M. Gribble, Guy A. Rutter
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1275-1286 (2014)
Liver kinase B1 (LKB1; also known as STK11) is a serine/threonine kinase and tumour suppressor that is mutated in Peutz-Jeghers syndrome (PJS), a premalignant syndrome associated with the development of gastrointestinal polyps. Proglucagon-expressing
Externí odkaz:
https://doaj.org/article/7a4c3905c6084f389f2c2c6618256a19
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 2, Pp 193-202 (2011)
SUMMARY Axon degeneration is observed in neurodegenerative diseases and neuroinflammatory disorders, such as Alzheimer’s disease, Parkinson’s disease and multiple sclerosis. The molecular basis of this process remains largely unknown. Here, we sh
Externí odkaz:
https://doaj.org/article/c21d494c54614c389c2f4de917cf10f6
Autor:
Zachary Gao Sun, Vikrant Yadav, Sorosh Amiri, Wenxiang Cao, Enrique M. De La Cruz, Michael Murrell
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 1, Pp 151379- (2024)
The organization of actin filaments (F-actin) into crosslinked networks determines the transmission of mechanical stresses within the cytoskeleton and subsequent changes in cell and tissue shape. Principally mediated by proteins such as α-actinin, F
Externí odkaz:
https://doaj.org/article/07517b2f4f854a6bb922ac8321294967
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/28867b2ef6e74aefb1ff25ca30f062f8
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundSeveral studies have compared the effects of fixed and flexible gonadotropin releasing hormone antagonist (GnRH-ant) protocols during in vitro fertilization and embryo transfer (IVF-ET). However, which GnRH-ant initiation strategy is better
Externí odkaz:
https://doaj.org/article/6355763746364a5fa3ef94f85c4d6c9c
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
BackgroundThe use of frozen embryo transfer (FET) has grown exponentially over the past few years. However, in clinical practice, there are no specific criteria as to whether a delay of at least one menstrual cycle is required for an FET after a fail
Externí odkaz:
https://doaj.org/article/f62172377bdc44aabe6533de2fb59d0a