Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ganwei Lu"'
Autor:
Harry C. Blair, Tamer M Hadi, Jolene J. Windle, Verónica García-Palacios, Christina S. Boykin, Noriyoshi Kurihara, G. David Roodman, Ganwei Lu, Deborah L. Galson, Heju Zhang, Sun Jin Choi, Hisako Ishizuka, Kenneth D. Patrene, Liena Zhao, Mark A. Subler
Publikováno v:
Journal of Bone and Mineral Research
ADAM8 expression is increased in the interface tissue around a loosened hip prosthesis and in the pannus and synovium of patients with rheumatoid arthritis, but its potential role in these processes is unclear. ADAM8 stimulates osteoclast (OCL) forma
Autor:
Irene M. Ghobrial, Hai Ngo, Michael Timm, Xiaoying Jia, Xavier Leleu, G. David Roodman, Lori A. Ehrlich, Yazan Alsayed, Suzanne Lentzsch, Elizabeth A. Dimmock, Ganwei Lu, Teru Hideshima, Judith L. Anderson, Alissa Huston, Ujjal K. Singha, Lanie Francis, Kenneth C. Anderson
Publikováno v:
Clinical Cancer Research. 12:6826-6835
Purpose: The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (mTOR) pathway and the heat shock protein family are up-regulated in multiple myeloma and are both regulators of the cyclin D/retinoblastoma pathway, a critical pathway in m
Autor:
Judith L. Anderson, Ganwei Lu, G. David Roodman, Hidefumi Maeda, Robin J. Leach, Sakamuri V. Reddy, Noriyoshi Kurihara
Publikováno v:
Journal of Biological Chemistry. 281:30542-30550
Annexin II is a heterotetramer, consisting of two 11-kDa (p11) and two 36-kDa (p36) subunits, that is produced by osteoclasts and stimulates osteoclast formation. However, its receptor is unknown. We showed that annexin II binds to normal primary hum
Autor:
Harry C. Blair, Dean Sheppard, Ken Patrene, Verónica García-Palacios, Sun Jin Choi, Ganwei Lu, Jolene J. Windle, Hiroshi Kajiya, Noriyoshi Kurihara, G. David Roodman, Hongwei Rao, Judy Anderson
Publikováno v:
Journal of Bone and Mineral Research. 21:1657-1665
We identified a previously unknown integrin, alpha(9)beta(1), on OCLs and their precursors. Antibody to alpha(9) inhibited OCL formation in human marrow cultures, and OCLs from alpha(9) knockout mice had a defect in actin ring reorganization and an i
Autor:
Petar J. Popovic, Ayan K. Chakrabarti, Valeria P. Makarenkova, Simon C. Watkins, Nikola L. Vujanovic, Jennifer A. Liberatore, Ganwei Lu
Publikováno v:
Journal of Leukocyte Biology. 77:408-413
Dendritic cells (DC) and natural killer (NK) cells are essential components of the innate immune system, which rapidly sense and eliminate invading pathogens and transformed cells, mediate inflammation, and initiate adaptive immune responses. During
Autor:
Qiming Jane Wang, Ganwei Lu, Walter A. Schlapkohl, Axel Goerke, Christer Larsson, Harald Mischak, Peter M. Blumberg, J. Frederic Mushinski
Publikováno v:
Molecular Cancer Research. 2:129-140
The catalytic domain of overexpressed protein kinase C (PKC)-δ mediates phorbol 12-myristate 13-acetate (PMA)-induced differentiation or apoptosis in appropriate model cell lines. To define the portions of the catalytic domain that are critical for
Autor:
Jelena M. Janjic, Nikola L. Vujanovic, Bratislav Janjic, Ganwei Lu, Walter J. Storkus, Theresa L. Whiteside
Publikováno v:
The Journal of Immunology. 168:1831-1839
Our recent studies have demonstrated that human immature dendritic cells (DCs) are able to directly and effectively mediate apoptotic killing against a wide array of cultured and freshly-isolated cancer cells without harming normal cells. In the pres
Autor:
Jianhua Wang, Younghun Jung, Aaron M. Havens, Elisabeth A. Pedersen, Jingcheng Wang, Robert D. Loberg, Anne M. Ziegler, Yusuke Shiozawa, G. David Roodman, Russell S. Taichman, Kenneth J. Pienta, Ganwei Lu
One of the most life-threatening complications of prostate cancer is skeletal metastasis. In order to develop treatment for metastasis, it is important to understand its molecular mechanisms. Our work in this field has drawn parallels between hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3251d93cdefc26a7e895fe44b6e53a
https://europepmc.org/articles/PMC3614912/
https://europepmc.org/articles/PMC3614912/
Autor:
Hai Ngo, Mona F. Melhem, Alexey A. Leontovich, Morie A. Gertz, Rafael Fonseca, Yazan Alsayed, Steven P. Treon, Diane George, Evdoxia Hatjiharissi, Irene M. Ghobrial, Kenneth C. Anderson, Michael Timm, Xavier Leleu, Xiaoying Jia, Anne Moreau, Steven C. Zeismer, Thomas E. Witzig, Ganwei Lu, Miguel E. Cabanela, Alex Nehme, Joanna M. Ghobrial
Publikováno v:
Cancer research. 67(8)
To better understand the molecular changes that occur in Waldenstrom macroglobulinemia (WM), we employed antibody-based protein microarrays to compare patterns of protein expression between untreated WM and normal bone marrow controls. Protein expres
Autor:
Joanna M. Ghobrial, G. David Roodman, Xavier Leleu, Irene M. Ghobrial, Teru Hideshima, Costas Pitsillides, Kenneth C. Anderson, Yazan Alsayed, Ashok Kumar, Ganwei Lu, Andrew L. Kung, Charles P. Lin, Teresa K. Kimlinger, Joel A. Spencer, Michael Timm, Judith Runnels, Karen E. Hedin, Xiaoying Jia, Hai Ngo, Ujjal K. Singha, Thomas E. Witzig, Daniel Côté, I. Veilleux
The mechanisms by which multiple myeloma (MM) cells migrate and home to the bone marrow are not well understood. In this study, we sought to determine the effect of the chemokine SDF-1 (CXCL12) and its receptor CXCR4 on the migration and homing of MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01a94f6da85270355862451f140909a
https://hdl.handle.net/20.500.14279/1672
https://hdl.handle.net/20.500.14279/1672