The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment

Autor: Kalogera, Stefania, He, Yi, Bay-Jensen, Anne-Christine, Gantzel, Thorbjørn, Sun, Shu, Manon-Jensen, Tina, Karsdal, Morten Asser, Thudium, Christian S.

Publikováno v: Kalogera, S, He, Y, Bay-Jensen, A C, Gantzel, T, Sun, S, Manon-Jensen, T, Karsdal, M A & Thudium, C S 2021, ' The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment ', Scientific Reports, vol. 11, no. 1, 24285 . https://doi.org/10.1038/s41598-021-03346-0
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
He, Yi
Scientific Reports

Osteoarthritis (OA) and rheumatoid arthritis (RA) are serious and painful diseases. Protease-activated receptor 2 (PAR2) is involved in the pathology of both OA and RA including roles in synovial hyperplasia, cartilage destruction, osteophyogenesis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a471ad2477ec340181d7491bdd056c
https://doi.org/10.1038/s41598-021-03346-0

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A Highly Sensitive Biomarker of Type II Collagen C-Terminal Pro-Peptide Associated with Cartilage Formation.

Autor: Port H; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 København, Denmark., Bay-Jensen AC; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark., He Y; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark., Karsdal MA; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark., Gantzel T; Orthopedic Surgery Unit, Gentofte University Hospital, 2820 Gentofte, Denmark., Thudium CS; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark., Holm Nielsen S; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 27; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 27.