Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ganta Madhusudhan Reddy"'
Autor:
Ganta Madhusudhan Reddy, V. V. N. K. V. Prasada Raju, Kisara Satyanarayana, G. Venkateshwarlu, Vedantham Ravindra
Publikováno v:
Synthetic Communications. 43:425-430
Synthesis of valganciclovir 1, a potent anticytomegalovirus (CMV) prodrug of ganciclovir 2, is described. The synthetic procedure involves protection–deprotection and reductive dehalogenation.
Autor:
Ghanta Mahesh Reddy, Mandava Venkata Naga Brahmeswara Rao, Khagga Mukkanti, Vajrala Venkata Reddy, Ganta Madhusudhan Reddy
Publikováno v:
Synthetic Communications. 42:3513-3523
Vardenafil hydrochloride trihydrate (Levitra) is used to treat erectile dysfunction (ED) and is an inhibitor of phosphodiesterase type 5 (PDE-5) enzyme. It maintains higher levels of cyclic guanosine monophosphate (cGMP), relaxes smooth muscles, prom
Autor:
Khagga Mukkanti, Cherukupally Praveen, Varanasi Ganesh, Mandava Venkata Naga Brahmeswara Rao, Vajrala Venkata Reddy, Adla Vijaya Kumar, Ganta Mahesh Reddy, Ganta Madhusudhan Reddy
Publikováno v:
Letters in Organic Chemistry. 7:149-154
Publikováno v:
Letters in Organic Chemistry. 7:45-49
Autor:
Ghanta Mahesh Reddy, Pingili Ramchandra Reddy, Ganta Madhusudhan Reddy, Lilakar Jaydeepkumar, Vurimidi Himabindu, Jonnalagadda Vijaya Kumar
Publikováno v:
Organic Process Research & Development. 13:896-899
The present work details the journey towards development of a simple and cost-viable process for large-scale synthesis of rabeprazole sodium substantially free from the impurities. The detailed study of different parameters affecting the quality and
Autor:
Ganta Madhusudhan Reddy, P. K. Dubey, Vijayavitthal T. Mathad, V. V. N. K. V. Prasada Raju, Vedantham Ravindra, Padi Pratap Reddy
Publikováno v:
Synthetic Communications. 39:2137-2145
Five related substances (impurities) were detected in lacidipine bulk drug substance by a simple high-performance liquid chromatographic method (HPLC) and were identified by liquid chromatography–mass spectrometry (LC-MS). These related substances
Publikováno v:
Synthetic Communications. 39:278-290
Rabeprazole sodium (Aciphex®) is a gastric proton pump inhibitor used for the prevention and treatment of gastric acid–related diseases. During the synthesis of bulk drug of rabeprazole sodium, we have observed metabolites rabeprazole sulfide and
Publikováno v:
Synthetic Communications. 38:3477-3489
Lansoprazole (Prevacid) is an antiulcerative drug used for the treatment of duodenal and gastric ulcers, reflux oesophagitis, and Zollinger–Ellison syndrome. During the bulk synthesis of lansoprazole, we have observed five impurities: lansoprazole
Autor:
V. V. N. K. V. Prasada Raju, Mayur Devjibhai Khunt, Ganta Madhusudhan Reddy, Padi Pratap Reddy, J. Moses Babu, Ch. Praveen, K. Mukkanti
Publikováno v:
Synthetic Communications. 38:1725-1736
Tenatoprazole (Ulsacare®) is a recently developed antiulcerative drug used for the treatment of both erosive and nonerosive gastroesophageal reflux disease. During the bulk synthesis of tenatoprazole, we have observed four impurities (tenatoprazole
Autor:
Krishnamurthi Vyas, S. Ashok, Ganta Madhusudhan Reddy, B. Vijaya Bhaskar, K. Mukkanti, P. Pratap Reddy, J. Moses Babu, P. C. Sudhakar
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 45:201-210
Six impurities in pantoprazole sodium bulk drug substance were detected by a simple high performance liquid chromatographic method (HPLC) whose area percentage ranged from ∼0.05 to 0.34%. Liquid chromatography–mass spectrometry (LC–MS) was perf