Lumasiran for Advanced Primary Hyperoxaluria Type 1: Phase 3 ILLUMINATE-C Trial

Autor: Michael, M., Groothoff, J. W., Shasha-Lavsky, H., Lieske, J. C., Frishberg, Y., Simkova, E., Sellier-Leclerc, A. L., Devresse, A., Guebre-Egziabher, F., Bakkaloglu, S. A., Mourani, C., Saqan, R., Singer, R., Willey, R., Habtemariam, B., Gansner, J. M., Bhan, I., Mcgregor, T., Magen, D.

Publikováno v: American journal of kidney diseases, 81(2), 145-155.e1. W.B. Saunders Ltd
American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 81, no.2, p. 145-155.e1 (2023)
American Journal of Kidney Diseases, (2022)
American Journal of Kidney Diseases
American Journal of Kidney Diseases, 2022, S0272-6386 (22), pp.00771-5. ⟨10.1053/j.ajkd.2022.05.012⟩

Rationale & Objective: Lumasiran reduces urinary and plasma oxalate (POx) in patients with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ILLUMINATE-C evaluates the efficacy, safety, pharmacokinetics, and pharmacodynamic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e766f52870784a99182763b902908469
https://doi.org/10.1053/j.ajkd.2022.05.012

ILLUMINATE-A, une étude de phase 3 du lumasiran, un ARNi thérapeutique expérimental, chez les enfants et les adultes atteints d’hyperoxalurie primaire de type 1

Autor: Garrelfs, S., Frishberg, Y., Hulton, S., Koren, M., O’Riordan, W., Cochat, P., Deschenes, G., Shasha-Lavsky, H., Saland, J., van’t Hoff, W., Fuster, D., Magen, D., Moochhala, S., Schalk, G., Simkova, E., Groothoff, J., Sas, D., Meliambro, K., Lu, J., Garg, P., Gansner, J., McGregor, T., Lieske, J.

Publikováno v: In Nephrologie et Thérapeutique September 2020 16(5):262-262

Thymoma‐associated autoimmune encephalitis: Analysis of factors determining prognosis.

Autor: Song, Wenli¹ (AUTHOR), Li, Keru¹ (AUTHOR), Li, Jiao¹ (AUTHOR), Liu, Xiaoni^2,3 (AUTHOR), Wu, Xiaoke¹ (AUTHOR), Xu, Xiaodong¹ (AUTHOR), Xiong, Kangping¹ (AUTHOR), Chen, Xiangjun^2,3,4 (AUTHOR) xiangjchen@fudan.edu.cn, Zhang, Yanlin¹ (AUTHOR) zhangyanlin0012006@163.com

Publikováno v: CNS Neuroscience & Therapeutics. May2023, Vol. 29 Issue 5, p1213-1221. 9p.

Ventricular Tachycardia in a Pediatric Patient with High-Risk Thrombotic Thrombocytopenia Purpura.

Autor: Kratochvil, Taylor J.^1,2,3 (AUTHOR), Robinson, Jeffrey A.^4,5 (AUTHOR)

Publikováno v: Case Reports in Cardiology. 1/18/2023, Vol. 2023, p1-4. 4p.

Dynamic crosstalk between hematopoietic stem cells and their niche from emergence to aging.

Autor: Deng ZH; Center for cell lineage and development, CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China., Ma LY; Center for cell lineage and development, CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China., Chen Q; Center for cell lineage and development, CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China., Liu Y; School of Medicine, South China University of Technology, Guangzhou, China.

Publikováno v: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2023 Mar; Vol. 45 (3), pp. e2200121. Date of Electronic Publication: 2023 Jan 27.