Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level.

Autor: Liao TW; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Huang L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China., Wilson TJ; Nucleic Acid Structure Research Group, MSI/WTB Complex, The University of Dundee, Dundee, Dow Street, Dundee DD1 5EH, UK., Ganser LR; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Lilley DMJ; Nucleic Acid Structure Research Group, MSI/WTB Complex, The University of Dundee, Dundee, Dow Street, Dundee DD1 5EH, UK., Ha T; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Baltimore, MD, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2023 Sep 22; Vol. 51 (17), pp. 8957-8969.

Switch-like compaction of poly(ADP-ribose) upon cation binding.

Autor: Badiee M; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205., Kenet AL; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205., Ganser LR; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218., Paul T; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218., Myong S; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218., Leung AKL; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.; Department of Molecular Biology and Genetics, School of Medicine, Johns Hopkins University, Baltimore, MD 21205.; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205.; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 09; Vol. 120 (19), pp. e2215068120. Date of Electronic Publication: 2023 May 01.

Nucleation and dissolution mechanism underlying amyotrophic lateral sclerosis/frontotemporal lobar dementia-linked fused in sarcoma condensates.

Autor: Djaja NA; Program in Cellular Molecular Developmental Biology and Biophysics, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA., Chang MT; Department of Biophysics, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA., Beinart FR; Department of Biology, Kenyon College, 106 College Park Dr, Gambler, OH 43022, USA., Morris VM; Lymphoid Malignancy Branch, National Cancer Institute, National Institutes of Health, Building 10, Bethesda, MD 20814, USA., Ganser LR; Department of Biophysics, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA., Myong S; Program in Cellular Molecular Developmental Biology and Biophysics, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA.; T.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA.

Publikováno v: IScience [iScience] 2023 Mar 31; Vol. 26 (4), pp. 106537. Date of Electronic Publication: 2023 Mar 31 (Print Publication: 2023).

Poly(ADP-ribose) drives condensation of FUS via a transient interaction.

Autor: Rhine K; Program in Cell, Molecular, Developmental Biology, and Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA., Dasovich M; Chemistry-Biology Interface Program, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA., Yoniles J; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Badiee M; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA., Skanchy S; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Ganser LR; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Ge Y; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA., Fare CM; Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Shorter J; Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Leung AKL; Chemistry-Biology Interface Program, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Molecular Biology and Genetics, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; McKusick-Nathans Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. Electronic address: anthony.leung@jhu.edu., Myong S; Program in Cell, Molecular, Developmental Biology, and Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA; Physics Frontier Center (Center for the Physics of Living Cells), University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address: smyong@jhu.edu.

Publikováno v: Molecular cell [Mol Cell] 2022 Mar 03; Vol. 82 (5), pp. 969-985.e11. Date of Electronic Publication: 2022 Feb 18.