Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gannon Cottone"'
Autor:
Shivangi Yadav, Ranya Virk, Carolina H. Chung, Mariana Bustamante Eduardo, David VanDerway, Duojiao Chen, Kirsten Burdett, Hongyu Gao, Zexian Zeng, Manish Ranjan, Gannon Cottone, Xiaoling Xuei, Sriram Chandrasekaran, Vadim Backman, Robert Chatterton, Seema Ahsan Khan, Susan E. Clare
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Improved understanding of local breast biology that favors the development of estrogen receptor negative (ER−) breast cancer (BC) would foster better prevention strategies. We have previously shown that overexpression of specific lipid met
Externí odkaz:
https://doaj.org/article/52f370b4b3ad414294bef582910b2c61
Autor:
Manish Ranjan, Oukseub Lee, Gannon Cottone, Elnaz Mirzaei Mehrabad, Benjamin T. Spike, Zexian Zeng, Shivangi Yadav, Robert Chatterton, J. Julie Kim, Susan E. Clare, Seema A. Khan
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background The ovarian hormones estrogen and progesterone (EP) are implicated in breast cancer causation. A specific consequence of progesterone exposure is the expansion of the mammary stem cell (MSC) and luminal progenitor (LP) compartment
Externí odkaz:
https://doaj.org/article/54ebd66fced14276b1e7e69565c3d521
Autor:
Shivangi Yadav, Ranya Virk, Carolina H. Chung, Mariana Bustamante Eduardo, David VanDerway, Duojiao Chen, Kirsten Burdett, Hongyu Gao, Zexian Zeng, Manish Ranjan, Gannon Cottone, Xiaoling Xuei, Sriram Chandrasekaran, Vadim Backman, Robert Chatterton, Seema Ahsan Khan, Susan E. Clare
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0482c004ab534c9386ad84675aab7af9
Publikováno v:
Cancer Research. 83:P6-11
Introduction. The identification of women specifically at risk for estrogen receptor negative breast cancer (ER- BC) and the targeted treatment of this disease are significantly unmet clinical needs. We analyzed the gene expression profiles of epithe
Publikováno v:
Cancer Research. 83:P6-11
Introduction: The identification of women specifically at risk for estrogen receptor negative breast cancer (ER-BC) and the targeted treatment of this disease are significantly unmet clinical needs. To that end, we analyzed the gene expression profil
Publikováno v:
Cancer Research. 82:P3-13
Background: Women carrying a germline BRCA1 mutation, have 60% risk of developing breast cancer during their lifetime and frequently develop triple-negative, basal-like, aggressive breast tumors. Humans produce around 150,000 different proteins from
Publikováno v:
Cancer Research. 82:P3-09
Background: As bulk and single-cell RNA (scRNA) sequencing studies and data continue to accrue to publicly accessible databases, bioinformatic tools continue being developed to analyze these datasets. The resulting pipelines often focus on either bul
Autor:
Shivangi Yadav, Ranya Virk, Carolina H. Chung, Mariana Bustamante Eduardo, David VanDerway, Duojiao Chen, Kirsten Burdett, Hongyu Gao, Zexian Zeng, Manish Ranjan, Gannon Cottone, Xiaoling Xuei, Sriram Chandrasekaran, Vadim Backman, Robert Chatterton, Seema Ahsan Khan, Susan E. Clare
Publikováno v:
NPJ breast cancer. 8(1)
Improved understanding of local breast biology that favors the development of estrogen receptor negative (ER−) breast cancer (BC) would foster better prevention strategies. We have previously shown that overexpression of specific lipid metabolism g
Autor:
Kum Chuan Shim, Yoel E. Stuart, Nicholas C. Herrmann, Heather Falkner, Kiyoko M. Gotanda, Jacob LaFond, Gannon Cottone, Ambika Kamath, Todd S. Campbell
Publikováno v:
Evolution; international journal of organic evolutionLITERATURE CITED. 74(10)
Negative interactions between species can generate divergent selection that causes character displacement. However, other processes cause similar divergence. We use spatial and temporal replication across island populations of Anolis lizards to asses
Autor:
Gannon Cottone, Batzaya Davaadelger, J. Julie Kim, Shivangi Yadav, Seema A. Khan, Susan E. Clare
Publikováno v:
Cancer Research. 81:PS19-09
Background: Progesterone (P) and progestin are instrumental in the breast cancer risk associated with reproductive hormones. Progesterone receptor (PR) signaling has been shown to be inhibited by the wild-type BRCA1 protein and it is hypothesized tha