Precise control of microfluidic flow conditions is critical for harnessing the in vitro transfection capability of pDNA-loaded lipid-Eudragit nanoparticles.

Autor: Santhanes D; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia., Zhang H; Electron Microscopy and X-Ray Unit, Research and Innovation Division, University of Newcastle, Callaghan, NSW, 2308, Australia., Wilkins A; School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, 2308, Australia., Aitken RJ; School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, 2308, Australia., Gannon AL; School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, 2308, Australia., Liang M; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia. roger.liang@newcastle.edu.au.

Publikováno v: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Nov; Vol. 14 (11), pp. 3055-3069. Date of Electronic Publication: 2024 Feb 12.

A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function.

Autor: Gannon AL; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Darbey AL; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Chensee G; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Lawrence BM; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., O'Donnell L; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Kelso J; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Reed N; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Parameswaran S; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Smith S; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia., Smith LB; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia.; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.; Office for Research, Griffith University, Southport, QLD 4222, Australia., Rebourcet D; College of Engineering, Science and Environment, The University of Newcastle, Callaghan, NSW 2308, Australia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 30; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 30.

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

Autor: Gannon AL; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom.; School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Callaghan, NSW, Australia., O'Hara L; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom.; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, Edinburgh, United Kingdom., Mason IJ; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom., Jørgensen A; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, Copenhagen, Denmark., Frederiksen H; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, Copenhagen, Denmark., Curley M; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom., Milne L; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom., Smith S; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom., Mitchell RT; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom., Smith LB; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, United Kingdom.; School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Callaghan, NSW, Australia.

Publikováno v: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2021 Jan 21; Vol. 11, pp. 599869. Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2020).

Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders.

Autor: Gannon AL; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.; School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Callaghan, 2308, NSW, Australia., O'Hara L; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.; Centre for Discovery Brain Sciences, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK., Mason JI; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK., Rebourcet D; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.; School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Callaghan, 2308, NSW, Australia., Smith S; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK., Traveres A; Edinburgh Preclinical Imaging, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Alcaide-Corral CJ; Edinburgh Preclinical Imaging, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, EH16 4TJ, UK., Frederiksen H; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, Denmark., Jørgensen A; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, Denmark., Milne L; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK., Mitchell RT; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK., Smith LB; MRC Centre for Reproductive Health, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK. Lee.Smith@ed.ac.uk.; School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Callaghan, 2308, NSW, Australia. Lee.Smith@ed.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2019 Mar 01; Vol. 9 (1), pp. 3250. Date of Electronic Publication: 2019 Mar 01.

ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells.

Autor: Vaidyanathan A; Division of Cancer Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Sawers L; Division of Cancer Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Gannon AL; Division of Cancer Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Chakravarty P; Bioinformatics and Biostatistics Service, Cancer Research UK, 44 Lincolns Inn Fields, London WC2A 3PX, UK., Scott AL; Division of Cancer Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Bray SE; Tayside Tissue Bank, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Ferguson MJ; NHS Tayside, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Smith G; Division of Cancer Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

Publikováno v: British journal of cancer [Br J Cancer] 2016 Aug 09; Vol. 115 (4), pp. 431-41. Date of Electronic Publication: 2016 Jul 14.