Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Ganna V. Kalayda"'
Autor:
Sophie Möltgen, Eleonora Piumatti, Giuseppe M. Massafra, Sabine Metzger, Ulrich Jaehde, Ganna V. Kalayda
Publikováno v:
Cells, Vol 9, Iss 6, p 1322 (2020)
Cisplatin is a widely used drug in the treatment of various solid tumors, such as ovarian cancer. However, while the acquired resistance significantly limits the success of therapy, some tumors, such as colorectal cancer, are intrinsically insensitiv
Externí odkaz:
https://doaj.org/article/ab749920f29540d0badb67fccf0e84e7
Autor:
Shahana Dilruba, Alessia Grondana, Anke C. Schiedel, Naoto T. Ueno, Chandra Bartholomeusz, Jindrich Cinatl Jr, Katie-May McLaughlin, Mark N. Wass, Martin Michaelis, Ganna V. Kalayda
Publikováno v:
Cells, Vol 9, Iss 2, p 515 (2020)
The efficacy of cisplatin-based chemotherapy in ovarian cancer is often limited by the development of drug resistance. In most ovarian cancer cells, cisplatin activates extracellular signal-regulated kinase1/2 (ERK1/2) signalling. Phosphoprotein enri
Externí odkaz:
https://doaj.org/article/d7ca6759aa7441a4bb97161a2063f3b4
Autor:
Navin Sarin, Florian Engel, Ganna V Kalayda, Mareike Mannewitz, Jindrich Cinatl, Florian Rothweiler, Martin Michaelis, Hisham Saafan, Christoph A Ritter, Ulrich Jaehde, Roland Frötschl
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181081 (2017)
The efficacy of cisplatin-based chemotherapy in cancer is limited by the occurrence of innate and acquired drug resistance. In order to better understand the mechanisms underlying acquired cisplatin resistance, we have compared the adenocarcinoma-der
Externí odkaz:
https://doaj.org/article/29faa58f678e40c0a520742228b169f6
Autor:
Navin Sarin, Florian Engel, Florian Rothweiler, Jindrich Cinatl, Martin Michaelis, Roland Frötschl, Holger Fröhlich, Ganna V. Kalayda
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 767 (2018)
The major obstacle in the clinical use of the antitumor drug cisplatin is inherent and acquired resistance. Typically, cisplatin resistance is not restricted to a single mechanism demanding for a systems pharmacology approach to understand a whole ce
Externí odkaz:
https://doaj.org/article/aa6c768df68e450ebc30ffc0d633e706
Autor:
Florian Holsboer, Julia C. Stingl, Abdul Karim Barakat, Ganna V. Kalayda, Michael Steffens, Marcus Ising, Susanne Lucae, Catharina Scholl, Kerstin Brandenburg, Gonzalo Laje, Ulrich Jaehde
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry, 10:210
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry, 10:210
Antidepressant therapy is still associated with delays in symptomatic improvement and low response rates. Incomplete understanding of molecular mechanisms underlying antidepressant effects hampered the identification of objective biomarkers for antid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e880878cc9a251727243f9ff10deac05
http://europepmc.org/articles/PMC7329820
http://europepmc.org/articles/PMC7329820
Autor:
Ganna V. Kalayda, Eleonora Piumatti, Giuseppe M Massafra, Sabine Metzger, Sophie Möltgen, Ulrich Jaehde
Publikováno v:
Cells
Volume 9
Issue 6
Cells, Vol 9, Iss 1322, p 1322 (2020)
Volume 9
Issue 6
Cells, Vol 9, Iss 1322, p 1322 (2020)
Cisplatin is a widely used drug in the treatment of various solid tumors, such as ovarian cancer. However, while the acquired resistance significantly limits the success of therapy, some tumors, such as colorectal cancer, are intrinsically insensitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7bc496d64a1e9b83f0fc3ea66c55e9
Autor:
Naoto T. Ueno, Ganna V. Kalayda, Alessia Grondana, Katie-May McLaughlin, Martin Michaelis, Shahana Dilruba, Mark N. Wass, Anke C. Schiedel, Chandra Bartholomeusz, Jindrich Cinatl
Publikováno v:
Cells
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 515 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 515 (2020)
The efficacy of cisplatin-based chemotherapy in ovarian cancer is often limited by the development of drug resistance. In most ovarian cancer cells, cisplatin activates extracellular signal-regulated kinase1/2 (ERK1/2) signalling. Phosphoprotein enri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ad9ce227f717c81aefd35f65461b94
https://kar.kent.ac.uk/80336/1/cells-09-00515-v2.pdf
https://kar.kent.ac.uk/80336/1/cells-09-00515-v2.pdf
Autor:
Ganna V. Kalayda, Shahana Dilruba
Publikováno v:
Cancer Chemotherapy and Pharmacology. 77:1103-1124
Platinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of human neoplasms. Their clinical success is, however, limited due to severe side effects and intrinsic or acquired resistance to the treatment. Much effort h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79669532af00d5c09f33511637e1748c
https://doi.org/10.1007/s00280-016-2976-z
https://doi.org/10.1007/s00280-016-2976-z
Autor:
Malte Hellwig, Ralf A. Hilger, Ulrich Jaehde, Maximilian Kullmann, Ganna V. Kalayda, Sabine Metzger, Sandra Kotz
Publikováno v:
Journal of Inorganic Biochemistry. 153:247-252
Intracellular binding of cisplatin to non-DNA partners, such as proteins, has received increasing attention as an additional mode of action and as mechanism of resistance. We investigated two cisplatin-interacting isoforms of protein disulfide isomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639669f756ea0bbc99deb9db26f33fd4
https://doi.org/10.1016/j.jinorgbio.2015.08.028
https://doi.org/10.1016/j.jinorgbio.2015.08.028
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 53:1041-1045
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e5805dced11fa7fa924cd1619dda68
https://doi.org/10.5414/cpxces14ea03
https://doi.org/10.5414/cpxces14ea03