Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ganlu Deng"'
Autor:
Yiming Qin, Xiongbing Zu, Yin Li, Ying Han, Jun Tan, Changjing Cai, Edward Shen, Ping Liu, Ganlu Deng, Ziyang Feng, Wantao Wu, Yinghui Peng, Yongting Liu, Jiayao Ma, Shan Zeng, Yihong Chen, Hong Shen
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107722- (2023)
Summary: Bladder cancer (BLCA) is one of the most prevalent and heterogeneous urinary malignant tumors. Previous researches have reported a significant association between cancer-associated fibroblasts (CAFs) and poor prognosis of tumor patients. How
Externí odkaz:
https://doaj.org/article/d1a2457d9074400c822f44ed288d04a9
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Hepatocellular carcinoma (HCC) is the deadliest malignancy. Long non-coding RNAs (lncRNAs) are involved in the development of multiple human malignancies. This study aimed to establish a reliable signature and identify novel biomarkers fo
Externí odkaz:
https://doaj.org/article/111063f794e2419e8c51c140938c2217
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundAs the prevalence of Hashimoto’s thyroiditis (HT) and thyroid cancer (TC) has been increasing dramatically in recent years, the association between the two diseases has been widely debated and studied. However, no consistent findings are
Externí odkaz:
https://doaj.org/article/1842ad1bf5f444f19043073575f29c27
Autor:
Ganlu Deng, Shan Zeng, Yanling Qu, Qingqing Luo, Cao Guo, Ling Yin, Ying Han, Yiyi Li, Changjing Cai, Yaojie Fu, Hong Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Abstract Background Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role i
Externí odkaz:
https://doaj.org/article/d1b27030679a43e4bf5a316ef76ac1f1
Autor:
Shan Zeng, Yaojie Fu, Ling Yin, Cao Guo, Yihong Chen, Ying Han, Shaobin Wu, Ganlu Deng, Hong Shen, Changjing Cai
Publikováno v:
OncoTargets and Therapy. 13:1625-1635
Background Chemoresistance is a major obstacle to improving the survival rate of colorectal cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the forkhead box (Fox) transcription factor family, is reported to be an important regulat
BMP4 promotes the metastasis of gastric cancer by inducing epithelial-mesenchymal transition via Id1
Autor:
Ying Han, Ganlu Deng, Yiyi Li, Yaojie Fu, Changjing Cai, Hong Shen, Ling Yin, Yihong Chen, Cao Guo, Shan Zeng
Publikováno v:
Journal of Cell Science.
Epithelial-mesenchymal transition (EMT) is a crucial process for cancer cells to acquire metastatic potential, which primarily causes death in gastric cancer (GC) patients. Bone morphogenetic protein 4 (BMP4) is a member of the TGF-β family that pla
Autor:
Shan Zeng, Ying Han, Ling Yin, Hong Shen, Ganlu Deng, Cao Guo, Changjing Cai, Shanshan Liu, Yaojie Fu, Yiyi Li
Publikováno v:
Journal of Cellular Biochemistry. 119:7022-7031
Activation of autophagy significantly affects cancer cell behaviors, such as proliferation, differentiation, and invasiveness. Epithelial-to-mesenchymal transition (EMT) as an initial step of malignant transformation of cancer cells was linked to the
Autor:
Herbert L. Bonkovsky, Guqi Wang, Junli Ma, Yan Zhang, Ying Han, Yanling Qu, Ganlu Deng, Yiyi Li, Hong Shen, Changjing Cai, Shan Zeng, Ling Yin, Cao Guo
Publikováno v:
Cancer Letters. 411:117-129
Background Bone morphogenetic protein-4 (BMP4) is a key regulator of epithelial-mesenchymal transition (EMT), which is crucial for cancer cells to acquire chemoresistance. The effects of BMP4 on OXA sensitivity in HCC need to be elucidated. Methods F
Autor:
Ling Yin, Ying Han, Yan Zhang, Hong Shen, Cao Guo, Guqi Wang, Shan Zeng, Herbert L. Bonkovsky, Yanlin Qu, Ganlu Deng, Junli Ma, Yiyi Li, Changjing Cai
Publikováno v:
Cancer Letters. 390:67-76
The role of bone morphogenetic protein 4 (BMP4), a crucial epithelial–mesenchymal transition (EMT) mediator, in the progression of hepatocellular carcinoma (HCC) patients heretofore has not been elucidated. The present study analyzed BMP4 expressio
Autor:
Changjing Cai, Ying Han, Ling Yin, Cao Guo, Ganlu Deng, Junli Ma, Yiyi Li, Hong Shen, Shan Zeng, Yanlin Qu
Publikováno v:
Journal of Cancer
Background: Oxaliplatin (OXA) chemotherapy is widely used in the clinical treatment of colon cancer. However, chemo-resistance is still a barrier to effective chemotherapy in cases of colon cancer. Accumulated evidence suggests that the epithelial me