Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ganlan Bian"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The tumor microenvironment (TME) is variable across tumor types and has diverse effects on malignant progression, based on the type and number of infiltrating stromal cells. In particular, TME effector genes and their competitive endogenous RNA (ceRN
Externí odkaz:
https://doaj.org/article/53d99213d1a44dc2921b59cb47aad054
Autor:
Ling Liu, Kun Chen, Jun Song, Chao Fang, Jian Wang, Chunfeng Wu, Gong Ju, Caiyong Yu, Pan Ren, Kun Zhang, Ganlan Bian, Fangfang Liu, Dan Hu, Jie Xiang, Qian Zhang, Ruixia Sun
Publikováno v:
The FASEB Journal. 32:3597-3613
Spinster homolog 2 (SPNS2) is the membrane transporter of sphingosine-1-phosphate (S1P), and it participates in several physiologic processes by activating different S1P receptors (S1PRs). However, its functions in the nervous system remain largely u
Autor:
Qian Xue, Ganlan Bian, Jie Xiang, Qian Zhang, Jian Wang, Pan Ren, Hongmin Guo, Ruixia Sun, Fangfang Liu, Ling Liu, Gong Ju, Yu Zhao, Kun Zhang, Chao Fang, Wutian Wu, Jun Song, Sookja K. Chung, Caiyong Yu, Kun Chen
Publikováno v:
Science Signaling. 11
In many mammals, the eyelids migrate over the eye and fuse during embryogenesis to protect the cornea from damage during birth and early life. Loss-of-function mutations affecting the epidermal growth factor receptor (EGFR) signaling pathway cause an
Autor:
Yazhou Wang, Li Zhang, Chen Wang, Shengxi Wu, Dong Wang, Rou-Gang Xie, Mengmeng Wang, Ceng Luo, Youyi Zhao, Junjia Shan, Ganlan Bian, Chuchu Qi, Jiping Yang
Publikováno v:
Glia. 67(6)
Chronic pain is one of the most prevalent chronic diseases in the world. The plastic changes of sensory neurons in dorsal root ganglia (DRG) have been extensively studied as the underlying periphery mechanism. Recent studies revealed that satellite c
Autor:
Fangfang Liu, Caiyong Yu, Ling Liu, Kun Chen, Chao Fang, Kun Zhang, Jun Song, Gong Ju, Jian Wang, Qian Xue, Ganlan Bian
Publikováno v:
Molecular immunology. 114
Programmed cell death 1 ligand 1 (PD-L1) plays a critical role in mediating autoimmune diseases, including type I diabetes (T1D). B cells are important antigen-presenting cells (APCs) that make a major contribution to T1D development. However, B cell
Autor:
Ling Liu, Fangfang Liu, Bing Song, Chao Fang, Caiyong Yu, Angang Yang, Gong Ju, Kun Zhang, Jian Wang, Qian Xue, Ganlan Bian, Yan Wang
Publikováno v:
Scientific Reports
A single microRNA (miRNA) can regulate expression of multiple proteins and expression of an individual protein may be controlled by numerous miRNAs. This regulatory pattern strongly suggests that synergistic effects of miRNAs play critical roles in r
Autor:
Peng Chen, Qian Xue, Ganlan Bian, Gong Ju, Jian Wang, Caiyong Yu, Sookja K. Chung, Fangfang Liu, Ling Liu, Qian Zhang, Bing Song
Inflammatory reactions are the most critical pathological processes occurring after spinal cord injury (SCI). Activated microglia/macrophages have either detrimental or beneficial effects on neural regeneration based on their functional polarized M1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ced4971bdd1c08b1eaf826d45597ef
Autor:
Caiyong Yu, Ling Liu, Yu Zhao, Jian Wang, Ganlan Bian, Hongmin Guo, Jun Guo, Fangfang Liu, Gong Ju
Publikováno v:
Science China Life Sciences. 55:940-947
The inhibitory co-receptor programmed death 1 (PD-1, encoded by pdcd1) and its two ligands PD-L1 and PD-L2 comprise an important immune inhibitory signaling pathway for defense against microbes and for self-tolerance. Unlike other members of the B7-C
Autor:
Caiyong Yu, Qian Xue, Fangfang Liu, Gong Ju, Ganlan Bian, Ling Liu, Kun Zhang, Sookja K. Chung, Bing Song, Haifeng Zhang, Jingjing Zheng, Jian Wang
Publikováno v:
Molecular Therapy
Spinal cord injury (SCI) frequently provokes serious detrimental outcomes because neuronal regeneration is limited in the central nervous system (CNS). Thus, the creation of a permissive environment for transplantation therapy with neural stem/progen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67aea2f4e74b34aa37fac4d79f434d33
https://orca.cardiff.ac.uk/id/eprint/116064/1/1-s2.0-S1525001616301356-main.pdf
https://orca.cardiff.ac.uk/id/eprint/116064/1/1-s2.0-S1525001616301356-main.pdf
Autor:
Ganlan Bian, Caiyong Yu, Kun Zhang, Gong Ju, Fangfang Liu, Jingjing Zheng, Liang Tang, Jian Wang, Kun Chen, Ling Liu, An-Hui Yao, Peng Cheng, Hongmin Guo
Publikováno v:
Neurotherapeutics
The inflammatory response following spinal cord injury (SCI) involves the activation of resident microglia and the infiltration of macrophages. Macrophages and microglia can be polarized into the classically activated proinflammatory M1 phenotype or