Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gani Oruqaj"'
Autor:
Eistine Boateng, Rocio Bonilla-Martinez, Barbara Ahlemeyer, Vannuruswamy Garikapati, Mohammad Rashedul Alam, Omelyan Trompak, Gani Oruqaj, Natalia El-Merhie, Michael Seimetz, Clemens Ruppert, Andreas Günther, Bernhard Spengler, Srikanth Karnati, Eveline Baumgart-Vogt
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung epithelial phenotypes, fibroblast activation, and increased extracellular matrix deposition. Transforming growth factor-beta (TGF-β)1-induced Smad signaling an
Externí odkaz:
https://doaj.org/article/497c1b77bedd4f42ab38ca4d615984cc
Autor:
Gani Oruqaj, Gabriele Krombach, Stefan Gattenloehner, Susanne Herold, István Vadász, Werner Seeger, Khodr Tello, Matthias Hecker
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionEndobronchial foreign body aspiration is not common in adults, but it is a life-threatening event. Recurrent pneumonias by chronic retention of foreign body often lead to initial medical presentation of the patient. However, lymphoplasmac
Externí odkaz:
https://doaj.org/article/b00373d39f0742c791515d64d77abb20
Autor:
Srikanth Karnati, Gani Oruqaj, Harshavardhan Janga, Srinu Tumpara, Claudia Colasante, Paul P Van Veldhoven, Nancy Braverman, Adrian Pilatz, Thomas J Mariani, Eveline Baumgart-Vogt
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203466 (2018)
Despite the important functions of PPARγ in various cell types of the lung, PPARγ-deficiency in club cells induces only mild emphysema. Peroxisomes are distributed in a similar way as PPARγ in the lung and are mainly enriched in club and AECII cel
Externí odkaz:
https://doaj.org/article/8b4fd6fea18d41279e2508bb98c1b19b
Autor:
Gani Oruqaj, Srikanth Karnati, Lakshmi Kanth Kotarkonda, Eistine Boateng, Marek Bartkuhn, Wenming Zhang, Clemens Ruppert, Andreas Günther, Laurent Bartholin, Wei Shi, Eveline Baumgart-Vogt
Publikováno v:
The American journal of pathology.
Idiopathic pulmonary fibrosis (IPF) is a chronic human disease with persistent destruction of lung parenchyma. A pivotal role in the initiation and pathogenesis of IPF is played by transforming growth factor (TGF)-β1 signaling. As shown herein, TGF-
Autor:
Thomas J. Mariani, Srikanth Karnati, Susanne Pfreimer, Eveline Baumgart-Vogt, Michael Seimetz, Tilman Graulich, Gani Oruqaj, Norbert Weissmann, Cordula Stamme, Christian Mühlfeld
Publikováno v:
Cell and Tissue Research. 364:543-557
Club (Clara) cells are nonciliated secretory epithelial cells present in bronchioles of distal pulmonary airways. So far, no information is available on the postnatal differentiation of club cells by a combination of molecular biological, biochemical
Autor:
Eveline Baumgart-Vogt, Srikanth Karnati, Saranya Palaniswamy, Cordula Stamme, Mohammad Rashedul Alam, Gani Oruqaj
Publikováno v:
Histochemistry and Cell Biology. 145:287-304
In pulmonary research, temperature-sensitive immortalized cell lines derived from the lung of the "immortomouse" (H-2k(b)-tsA58 transgenic mouse), such as C22 club cells and T7 alveolar epithelial cells type II (AECII), are frequently used cell cultu
Autor:
Wenming Zhang, Clemens Ruppert, Andreas Günther, Eistine Boateng, Gani Oruqaj, Vijith Vijayan, Eveline Baumgart-Vogt, Lakshmi Kanth Kotarkonda, Wei Shi, Srikanth Karnati
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Idiopathic pulmonary fibrosis (IPF) is a devastating disease, and its pathogenic mechanisms remain incompletely understood. Peroxisomes are known to be important in ROS and proinflammatory lipid degradation, and their deficiency induces liver fibrosi