Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Gangyi Yang"'
Autor:
Huawei Shen, Yafei Fu, Feifei Liu, Wanliang Zhang, Yin Yuan, Gangyi Yang, Mengliu Yang, Ling Li
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract As the pathophysiological basis of type 2 diabetes mellitus (T2DM), insulin resistance (IR) is closely related to oxidative stress (OS) and inflammation, while nanozymes have a good therapeutic effect on inflammation and OS by scavenging rea
Externí odkaz:
https://doaj.org/article/087bde1201c845b7910e253a5142d196
Autor:
Sheng Qiu, Qinan Wu, Hao Wang, Dongfang Liu, Chen Chen, Zhiming Zhu, Hongting Zheng, Gangyi Yang, Ling Li, Mengliu Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Zinc-alpha2-glycoprotein (AZGP1) has been implicated in peripheral metabolism; however, its role in regulating energy metabolism in the brain, particularly in POMC neurons, remains unknown. Here, we show that AZGP1 in POMC neurons plays a cr
Externí odkaz:
https://doaj.org/article/c93d618df6514905ab89cda957549f82
Publikováno v:
The Aging Male, Vol 27, Iss 1 (2024)
AbstractBackground Metabolic dysfunction and obesity are closely related to chronic kidney disease (CKD). However, studies on the relationship between various metabolic syndrome-body mass index (MetS-BMI) phenotypes and the risk of CKD in the Chinese
Externí odkaz:
https://doaj.org/article/9e00e5ba3e2040bf93f40ab8760a5611
Autor:
Yi Zheng, Yuren Wang, Xin Xiong, Linlin Zhang, Jiaran Zhu, Bangliang Huang, Xiufei Liu, Jinbo Liu, Zhiming Zhu, Gangyi Yang, Hua Qu, Hongting Zheng
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Glucagon receptor (GCGR) agonism offers potentially greater effects on the mitigation of hepatic steatosis. However, its underlying mechanism is not fully understood. Here, it screened tetraspanin CD9 might medicate hepatic effects of GCGR a
Externí odkaz:
https://doaj.org/article/953c2a076bc04ab486d4553d49c5fbb5
Autor:
Hua Qu, Xiufei Liu, Jiaran Zhu, Niexia He, Qingshan He, Linlin Zhang, Yuren Wang, Xiaoli Gong, Xin Xiong, Jinbo Liu, Chuan Wang, Gangyi Yang, Qingwu Yang, Gang Luo, Zhiming Zhu, Yi Zheng, Hongting Zheng
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109796- (2024)
Summary: Metabolic diseases such as obesity and diabetes induce lipotoxic cardiomyopathy, which is characterized by myocardial lipid accumulation, dysfunction, hypertrophy, fibrosis and mitochondrial dysfunction. Here, we identify that mitochondrial
Externí odkaz:
https://doaj.org/article/542d068c51524cd59aedf10830676b99
Autor:
Shiyao Xue, Jiaxiu Ling, Mingyuan Tian, Ke Li, Shengbing Li, Dongfang Liu, Ling Li, Mengliu Yang, Gangyi Yang
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30029- (2024)
Aims: This study aimed to examine the alterations in the serum CTRP7 and CTRP15 concentrations in patients newly diagnosed with type 2 diabetes mellitus (T2DM) and to assess the diagnostic potential of the log10 (CTRP7+CTRP15) for insulin resistance
Externí odkaz:
https://doaj.org/article/b745250385ba49e8857cf75ffd2e99ba
Publikováno v:
Journal of Analytical Science and Technology, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract MicroRNAs (miRNAs) play a significant role in the pathogenesis of various diseases throughout biological processes, and the accurate detection of miRNA biomarkers holds great potential for early stage disease diagnosis and treatment. In this
Externí odkaz:
https://doaj.org/article/4b1015b3c2af4dca9e68f8fb81a82069
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background C-reactive protein(CRP), is an inflammatory marker that weaken leptin bioavailability and insulin sensitivity to disturb energy and glucose metabolism. Polycystic ovary syndrome (PCOS) exhibit a metabolic component consisting of h
Externí odkaz:
https://doaj.org/article/b80b8e510d4a4833919b0da87d6f87cc
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1525-1536 (2023)
Metabolic cardiovascular diseases have become a global health concern, and some of their risk factors are linked to several metabolic disorders. They are the leading causes of death in developing countries. Adipose tissues secrete a variety of adipok
Externí odkaz:
https://doaj.org/article/1354a50f5649429585783ce70175facc
Autor:
Hao Wang, Yanping Wang, Hongmin Zhang, Zerong Liang, Wenjing Hu, Sheng Qiu, Ke Li, Lili Zhang, Han Dai, Mengliu Yang, Gangyi Yang, Ling Li
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground Although a study found a significant increase in serum hedgehog interacting protein (HHIP) concentrations in impaired fasting blood glucose, impaired glucose tolerance and newly diagnosed T2DM patients, the variation in circulating
Externí odkaz:
https://doaj.org/article/1e360206b5474bd2a3c2a95a777ff874