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Amidative Cyclization of Alkynyl Esters to Access Pyrazin-1(2H)‑ones: Application to the Synthesis of Peramine and Dibromophakellin.

Autor: Gangnale, Laxmikant D., Miriyala, Satya Ravi Teja, Pasunooti, Kalyan Kumar, Reddy, D. Srinivasa

Publikováno v: Journal of Organic Chemistry; 12/15/2023, Vol. 88 Issue 24, p17330-17344, 15p

Amidative Cyclization of Alkynyl Esters to Access Pyrazin-1(2 H )-ones: Application to the Synthesis of Peramine and Dibromophakellin.

Autor: Gangnale LD; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Miriyala SRT; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Pasunooti KK; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, United States., Reddy DS; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2023 Dec 15; Vol. 88 (24), pp. 17330-17344. Date of Electronic Publication: 2023 Dec 05.