Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gangmin Deng"'
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 245-252 (1998)
Expression of the growth arrest DNA damage-inducible protein,GADD45, has recently been reported to be induced by a wide range of stimuli, especially those that produce a high level of base pair damage. We have investigated the expression ofGADD45in b
Externí odkaz:
https://doaj.org/article/1c9f30b4f4624546a3de7ba18acee8f3
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 259-270 (1998)
We have isolated an ATP receptor clone by screening a bovine corpus callosum cDNA library. The clone includes one open reading frame encoding for a protein of 373 amino acid residues (42 kDa) which belongs to the G-protein-coupled receptor superfamil
Externí odkaz:
https://doaj.org/article/5b7eb67a197b48c09ffc674214750647
Publikováno v:
Neurobiology of Disease, Vol 4, Iss 5, Pp 365-375 (1997)
Neurofibrillary tangles and dystrophic neurites appear to develop in a highly characteristic spatial and temporal sequence in AD. In order to examine the nature of the cellular progression we have studied the trisynaptic entorhinal, dentate gyrus, CA
Externí odkaz:
https://doaj.org/article/bd356dcc60434e6f8218b4abcc9f9632
Publikováno v:
Journal of the American Society of Nephrology. 12:1892-1899
Interaction of reactive oxygen species with nitric oxide promotes nitric oxide inactivation and generation of cytotoxic reactive nitrogen species that attack DNA, lipids, and proteins. Nitration of free tyrosine and tyrosine residues of proteins resu
Publikováno v:
Nephrology Dialysis Transplantation. 14:1462-1466
Background Chronic renal failure (CRF) is associated with hypertriglyceridaemia and depressed plasma high-density lipoprotein (HDL)-cholesterol and apolipoprotein A-I (Apo A-I) concentrations. Uraemic hypertriglyceridaemia is due, in part, to lipopro
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 259-270 (1998)
We have isolated an ATP receptor clone by screening a bovine corpus callosum cDNA library. The clone includes one open reading frame encoding for a protein of 373 amino acid residues (42 kDa) which belongs to the G-protein-coupled receptor superfamil
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 245-252 (1998)
Expression of the growth arrest DNA damage-inducible protein, GADD45, has recently been reported to be induced by a wide range of stimuli, especially those that produce a high level of base pair damage. We have investigated the expression of GADD45 i
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 56:86-93
We have shown that many neurons in Alzheimer's disease (AD) exhibit terminal deoxynucleotidyl transferase (TdT) labeling for DNA strand breaks, and upregulation of Bcl-2 is associated with neurons exhibiting nuclear DNA fragmentation, while downregul
Publikováno v:
FEBS Letters. 397:50-54
Presenilin-2 is a gene of unknown function recently identified based upon linkage with some forms of familial Alzheimer's disease. To investigate potential effects of PS-2 on cell viability, rat pheochromocytoma (PC12) cells were stably transfected w
Publikováno v:
Experimental neurology. 159(1)
Oxidative stress is a major factor affecting the brain during aging and neurodegenerative diseases such as Alzheimer's disease (AD). Understanding the mechanisms by which neurons can be protected from oxidative stress, therefore, is critical for the