Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Ganglioside GD2"'
Autor:
Daniel V. Kalinovsky, Irina V. Kholodenko, Elena V. Svirshchevskaya, Alexey V. Kibardin, Dmitry Yu. Ryazantsev, Fedor N. Rozov, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8112-8125 (2023)
Oligomerization of antibody fragments via modification with polyethylene glycol (pegylation) may alter their function and properties, leading to a multivalent interaction of the resulting constructs with the target antigen. In a recent study, we gene
Externí odkaz:
https://doaj.org/article/bf8e0d4d6862409b924c8a06a327194f
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 5, Pp 777-784 (2023)
Objective To explore the feasibility of ganglioside GD2 as a marker for lung cancer stem cells (LCSCs). Methods Cancer stem cells (CSCs) of lung cancer cell lines were enriched by spheroid culturing in vitro; The expression of stemness-related genes
Externí odkaz:
https://doaj.org/article/d3cf2685c3f6488d981d8032ff7c3c95
Autor:
Yong-Liang Sha, Yun Liu, Jia-Xing Yang, Yang-Yang Wang, Bao-Cheng Gong, Yan Jin, Tong-Yuan Qu, Fan-Tong Xia, Lei Han, Qiang Zhao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)
Abstract Background Beta-1,3-galactosyltransferase-4 (B3GALT4) plays a critical regulatory role in tumor biology. However, the role of B3GALT4 in modulating the tumor microenvironment (TME) of neuroblastoma (NB) remains unknown. Methods Public datase
Externí odkaz:
https://doaj.org/article/d84f092e7cd040f799528f0a390c2e64
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Neuroblastoma (NB) is one of the most common solid tumors in children. Glycosyltransferases (GTs) play a crucial role in tumor development and immune escape and have been used as prognostic biomarkers in various tumors. However, the biological functi
Externí odkaz:
https://doaj.org/article/34422d09aa024307902f17c7e586dd64
Publikováno v:
Journal of Bone Oncology, Vol 28, Iss , Pp 100357- (2021)
Background: Osteosarcoma (OS) is the most common primary bone tumor and the third leading cause of pediatric cancer deaths. Liquid biopsies are an alternative to current diagnostic imaging modalities that can be used to monitor treatment efficacy and
Externí odkaz:
https://doaj.org/article/c393c9c136434686be930673e840370c
Akademický článek
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Autor:
Wieczorek, Holger N. Lode, Ruth Ladenstein, Sascha Troschke-Meurer, Linda Struppe, Nikolai Siebert, Maxi Zumpe, Karoline Ehlert, Stefanie Huber, Evgenia Glogova, Patrick Hundsdoerfer, Angelika Eggert, Anna Zaniewska-Tekieli, Walentyna Balwierz, Aleksandra
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3364
The anti-disialoganglioside (GD2) monoclonal antibody dinutuximab beta is approved for the maintenance treatment of high-risk neuroblastoma. Dinutuximab beta combined with different chemotherapy regimens is being investigated in various clinical sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9f56d6fe47ef7c0b475a4af7ee4fa43c
Autor:
Daniel V. Kalinovsky, Irina V. Kholodenko, Alexey V. Kibardin, Igor I. Doronin, Elena V. Svirshchevskaya, Dmitriy Y. Ryazantsev, Maria V. Konovalova, Fedor N. Rozov, Sergey S. Larin, Sergey M. Deyev, Roman V. Kholodenko
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1239
Ganglioside GD2 is a well-established target expressed on multiple solid tumors, many of which are characterized by low treatment efficiency. Antibody-drug conjugates (ADCs) have demonstrated marked success in a number of solid tumors, and GD2-direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e726fa50e723fc9f1d5c2294f92c7f5e
Autor:
Maxim Sorokin, Irina Kholodenko, Daniel Kalinovsky, Tatyana Shamanskaya, Igor Doronin, Dmitry Konovalov, Aleksei Mironov, Denis Kuzmin, Daniil Nikitin, Sergey Deyev, Anton Buzdin, Roman Kholodenko
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 142 (2020)
The tumor-associated ganglioside GD2 represents an attractive target for cancer immunotherapy. GD2-positive tumors are more responsive to such targeted therapy, and new methods are needed for the screening of GD2 molecular tumor phenotypes. In this w
Externí odkaz:
https://doaj.org/article/f3c8283c0f534e1091453307ac5af52a
Akademický článek
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