Evaluation of Dexamethasone-Eluting Cell-Seeded Constructs in a Preclinical Canine Model of Cartilage Repair.

Autor: Lee AJ; Department of Biomedical Engineering, Columbia University, New York, New York, USA., Gangi LR; Department of Biomedical Engineering, Columbia University, New York, New York, USA., Hu YJ; Department of Biomedical Engineering, Columbia University, New York, New York, USA., Dinescu AT; Department of Biomedical Engineering, Columbia University, New York, New York, USA., Guo XE; Department of Biomedical Engineering, Columbia University, New York, New York, USA., Bozynski CC; Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA., Kuroki K; Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA., Stoker AM; Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA., Marra KG; Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ateshian GA; Department of Biomedical Engineering, Columbia University, New York, New York, USA.; Department of Mechanical Engineering, Columbia University, New York, New York, USA., Cook JL; Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA., Hung CT; Department of Biomedical Engineering, Columbia University, New York, New York, USA.; Department of Orthopedic Surgery, Columbia University, New York, New York, USA.

Publikováno v: Tissue engineering. Part A [Tissue Eng Part A] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.

Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis.

Autor: Lee AJ; Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, Mail Code 8904, 1210 Amsterdam Avenue, New York, NY, USA. Electronic address: jl3924@columbia.edu., Gangi LR; Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, Mail Code 8904, 1210 Amsterdam Avenue, New York, NY, USA. Electronic address: lrg2147@columbia.edu., Zandkarimi F; Department of Chemistry, Columbia University, 216 Havemeyer Hall, 3000 Broadway, Mail Code 3183, New York, NY, USA. Electronic address: fz2262@columbia.edu., Stockwell BR; Department of Chemistry, Columbia University, 216 Havemeyer Hall, 3000 Broadway, Mail Code 3183, New York, NY, USA; Department of Biological Sciences, Columbia University, 1208 NWC Building, 550 West 120th St. M.C. 4846, New York, NY, USA. Electronic address: bstockwell@columbia.edu., Hung CT; Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, Mail Code 8904, 1210 Amsterdam Avenue, New York, NY, USA; Department of Orthopaedic Surgery, Columbia University, New York, NY, USA. Electronic address: cth6@columbia.edu.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Oct; Vol. 31 (10), pp. 1365-1376. Date of Electronic Publication: 2023 Jun 25.

Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear.

Autor: Pellicore MJ; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Gangi LR; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Murphy LA; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Lee AJ; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Jacobsen T; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Kenawy HM; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Shah RP; Department of Orthopedic Surgery, Columbia University, New York, NY, USA., Chahine NO; Department of Biomedical Engineering, Columbia University, New York, NY, USA; Department of Orthopedic Surgery, Columbia University, New York, NY, USA., Ateshian GA; Department of Orthopedic Surgery, Columbia University, New York, NY, USA; Department of Mechanical Engineering, Columbia University, New York, NY, USA., Hung CT; Department of Biomedical Engineering, Columbia University, New York, NY, USA; Department of Orthopedic Surgery, Columbia University, New York, NY, USA. Electronic address: cth6@columbia.edu.

Publikováno v: Journal of biomechanics [J Biomech] 2023 Feb; Vol. 148, pp. 111472. Date of Electronic Publication: 2023 Jan 26.

Attachment of cartilage wear particles to the synovium negatively impacts friction properties.

Autor: Estell EG; Columbia University, Department of Biomedical Engineering, New York, NY, United States., Murphy LA; Columbia University, Department of Biomedical Engineering, New York, NY, United States., Gangi LR; Columbia University, Department of Biomedical Engineering, New York, NY, United States., Shah RP; Columbia University, Department of Orthopedic Surgery, New York, NY, United States., Ateshian GA; Columbia University, Department of Biomedical Engineering, New York, NY, United States; Columbia University, Department of Mechanical Engineering, New York, NY, United States., Hung CT; Columbia University, Department of Biomedical Engineering, New York, NY, United States; Columbia University, Department of Orthopedic Surgery, New York, NY, United States. Electronic address: cth6@columbia.edu.

Publikováno v: Journal of biomechanics [J Biomech] 2021 Oct 11; Vol. 127, pp. 110668. Date of Electronic Publication: 2021 Aug 04.