Výsledky vyhledávání

Study on a New Numerical Method for Solving Heat Conduction Problems

Autor: Gangfeng Xu, Pengjie Liu, Ning Wang, Fucheng Pan, Lini Zhang, Weidong Shi

Publikováno v: 2019 2nd World Conference on Mechanical Engineering and Intelligent Manufacturing (WCMEIM).

In this paper, a new numerical method, the half boundary method (HBM) is studied. HBM reduced the order of the basic equation by substitution, and then calculated the relationship between the adjacent two nodes on the geometric model by integral solu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa2160a1f208ede02cdd319f78a9913f
https://doi.org/10.1109/wcmeim48965.2019.00083

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Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

Autor: S. Felzmann, D R Lowy, Gangfeng Xu, M. R. Johnson, William C. Vass, R. White, Jeffrey E. DeClue

Publikováno v: Molecular and Cellular Biology. 14:641-645

The NF1 gene, which is altered in patients with type 1 neurofibromatosis, has been postulated to function as a tumor suppressor gene. The NF1 protein product neurofibromin stimulates the intrinsic GTPase activity of active GTP-bound Ras, thereby inac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562f6a7092ede973616ad99d96e78e10
https://doi.org/10.1128/mcb.14.1.641-645.1994

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cDNA sequence and genomic structure of EVI2B, a gene lying within an intron of the neurofibromatosis type 1 gene

Autor: Francis S. Collins, David Viskochil, Ray White, Peter O'Connell, Nancy A. Jenkins, Douglas A. Marchuk, Richard M. Cawthon, Margaret R. Wallace, Jeff Stevens, Melanie Culver, Gangfeng Xu, Neal G. Copeland, Arthur M. Buchberg, Lone B. Andersen, Robert B. Weiss

Publikováno v: Genomics. 9:446-460

The gene responsible for neurofibromatosis type 1 (NF1), one of the more common inherited human disorders, was identified recently, and segments of it were cloned. Two translocation breakpoints that interrupt the NF1 gene in NF1 patients flank a 60-k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1c486d4f59479b7bd18852960231849
https://doi.org/10.1016/0888-7543(91)90410-g

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The Gene Encoding the Oligodendrocyte-Myelin Glycoprotein Is Embedded within the Neurofibromatosis Type 1 Gene

Autor: David Viskochil, Gangfeng Xu, Ray White, John C. Carey, Peter O'Connell, Richard M. Cawthon, Melanie Culver, Jeff Stevens

Publikováno v: Molecular and Cellular Biology. 11:906-912

In the course of efforts to identify the neurofibromatosis type 1 gene (NF1), three genes were found embedded within an intron of NF1. The cDNA sequence of one of these genes (OMGP) encodes oligodendrocyte-myelin glycoprotein. OMGP spans at least 2.7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882de093b4ff9f8797884b7201625e8d
https://doi.org/10.1128/mcb.11.2.906-912.1991

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The neurofibromatosis type 1 gene encodes a protein related to GAP

Autor: Margaret Robertson, Robert B. Weiss, Melanie Culver, Richard M. Cawthon, Gangfeng Xu, Diane M. Dunn, Ray White, Jeff Stevens, Raymond F. Gesteland, Peter O'Connell, David Viskochil

Publikováno v: Cell. 62:599-608

cDNA walking and sequencing have extended the open reading frame for the neurofibromatosis type 1 gene (NF1). The new sequence now predicts 2485 amino acids of the NF1 peptide. A 360 residue region of the new peptide shows significant similarity to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ed05bb51ef4fad44502a50389c2acc
https://doi.org/10.1016/0092-8674(90)90024-9

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A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

Autor: Diane M. Dunn, Ray White, Richard M. Cawthon, Gangfeng Xu, David Viskochil, Peter O'Connell, Jeff Stevens, Melanie Culver, Raymond F. Gesteland, Margaret Robertson, Robert B. Weiss

Publikováno v: Cell. 62:193-201

Overlapping cDNA clones from the translocation break-point region (TBR) gene, recently discovered at the neurofibromatosis type 1 locus and found to be interrupted by deletions and a t(17;22) translocation, have been sequenced. A 4 kb sequence of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9c3de3a28c1ac0a2de3b652d8a082a
https://doi.org/10.1016/0092-8674(90)90253-b

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Cyclin A-Kinase Binding to and Regulation of the Function of a Growth-Promoting Transcription Factor

Autor: Gangfeng Xu, David M. Livingston, Wilhelm Krek

Publikováno v: Cancer Genes ISBN: 9781461377047

Cyclin A function is required for a successful S phase of the mammalian cell cycle(Girard et al., 1991; Pagano et al., 1992; Zindy et al., 1992). In this role, it functions in complex with its cdk partner, cdk2 (Pines and Hunter, 1990), and it is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10e84751c10f028a7c5a2a349fd2c691
https://doi.org/10.1007/978-1-4615-5895-8_11

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Multiple members of the E2F transcription factor family are the products of oncogenes

Autor: Wilhelm Krek, Gangfeng Xu, David M. Livingston

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 92(5)

The retinoblastoma gene product (pRB) is a known tumor suppressor, capable of arresting growth in mid-to-late G1. Part of its growth suppression action arises from interaction(s) with one or more members of the E2F family of transcription factors. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15dbff90df367fd08aa22d6300ce256
https://pubmed.ncbi.nlm.nih.gov/7877982

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