Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gangde Zhao"'
Autor:
Shike Lou, Xiaoyin Wang, Fei Yuan, Gangde Zhao, Mingyang Feng, Yezhou Ding, Lanyi Lin, Kehui Liu, Xiaolin Wang, Wanqing Chi, Hui Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
This study investigated the potential of immune checkpoint inhibitors (ICIs) combined with chemotherapy as a promising treatment approach for malignancies. This report focuses on a patient with drug-induced liver injury (DILI) following the administr
Externí odkaz:
https://doaj.org/article/a1cc9b01e6e44e138b308e962bed9d49
Autor:
Shike Lou, Zhujun Cao, Wanqing Chi, Xiaoyin Wang, Mingyang Feng, Lanyi Lin, Yezhou Ding, Kehui Liu, Lihong Qu, Gangde Zhao, Shisan Bao, Hui Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Aim: To analyze the safety of immune checkpoint inhibitors in primary liver cancer patients and to identify the risk factors for immune-related adverse events (irAEs).Methods: The study enrolled 106 patients with primary liver cancer, including 81 wi
Externí odkaz:
https://doaj.org/article/be93bbaabd00471ab2a33a0cf5ff268d
Autor:
Yezhou Ding, Mingyang Feng, Di Ma, Gangde Zhao, Xiaolin Wang, Baoyan An, Yumin Xu, Shike Lou, Lanyi Lin, Qing Xie, Kehui Liu, Shisan Bao, Hui Wang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe clinical characteristics of primary liver cancer (PLC) patients are changing, maybe due to hepatitis viral vaccination and lifestyle changes, etc. The linkage between these changes and outcomes among these PLCs has not yet been fully el
Externí odkaz:
https://doaj.org/article/87663128b2e848ffaafdda2a6b986ec2
Autor:
Dabao Shang, Peng Wang, Weiliang Tang, Ruidong Mo, Rongtao Lai, Jie Lu, Ziqiang Li, Xiaolin Wang, Wei Cai, Hui Wang, Gangde Zhao, Qing Xie, Xiaogang Xiang
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2), members of the alcohol dehydrogenase family, have important roles in liver diseases. The roles of the polymorphisms of ADH1B rs1229984 and ALDH2 rs671 in hepatitis B virus (HBV) s
Externí odkaz:
https://doaj.org/article/e11fe8b86c9a49a986f9fabfb48c24f6
Autor:
Yan Huang, Qinyi Gan, Rongtao Lai, Weijing Wang, Simin Guo, Zike Sheng, Lu Chen, Qing Guo, Wei Cai, Hui Wang, Gangde Zhao, Zhujun Cao, Qing Xie
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Backgrounds and PurposeConcurrent non-alcoholic fatty liver disease (NAFLD) in chronic hepatitis B (CHB) patients is a frequent and increasingly concerning problem because of the NAFLD pandemic. Admittedly, NAFLD can progress to non-alcoholic steatoh
Externí odkaz:
https://doaj.org/article/c2af87f541834da59b8cf04f5a4f4710
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background and Aim: A prediction model of hepatocellular carcinoma (HCC) risk in patients with chronic liver diseases, based on age, male sex, albumin-bilirubin, and platelets (aMAP), has been previously reported. We validated the aMAP score and comp
Externí odkaz:
https://doaj.org/article/8e633822018f4230b20db2c6a2d124ac
Autor:
Liwen Chen, Chuanwu Zhu, Fengdi Li, Yun Wang, Rebecca Bao, Zhujun Cao, Xiaogang Xiang, Lei Yan, Lanyi Lin, Gangde Zhao, Qing Xie, Shisan Bao, Hui Wang
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Background Chronic hepatitis B (CHB) remains a global health dilemma with high morbidity and mortality. Human males absent on the first (hMOF) (a histone acetyltransferase) is responsible for DNA damage repair, tumorigenesis and cell cycle r
Externí odkaz:
https://doaj.org/article/afce2ec8c8544b868852e7af0c8e2ebb
Autor:
Yumin Xu, Hui Wang, Shishan Bao, Fazal Tabassam, Wei Cai, Xiaogang Xiang, Gangde Zhao, Haiqing Wu, Ting Gao, Hai Li, Qing Xie
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68757 (2013)
BackgroundAcute-on-chronic liver failure (ACLF) is an acute deterioration of established liver disease. Blocking the TNF (tumor necrosis factor)/TNFR (tumor necrosis factor receptor) 1 pathway may reduce hepatocyte apoptosis/necrosis, and subsequentl
Externí odkaz:
https://doaj.org/article/509d4d59493d41ff92e01a20d25824c0
Autor:
Shike Lou, Xiaolin Wang, Fei Yuan, Gangde Zhao, Lanyi Lin, Yezhou Ding, Kehui Liu, Qing Xie, Shisan Bao, Hui Wang
Immune checkpoint inhibitors (ICIs) are mAbs against cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed death-1 receptor (PD-1) and programmed death-ligand 1 (PD-L1), which the inhibitory pathways that leads to T cell inactivation. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861af16f8d668f51ce39da6e7d550ff0
https://doi.org/10.21203/rs.3.rs-1224141/v1
https://doi.org/10.21203/rs.3.rs-1224141/v1
Autor:
Hui Wang, Xiaogang Xiang, Minghao Cai, Qing Xie, Yumin Xu, Gangde Zhao, Wei Cai, Yuhan Liu, Zhujun Cao, Weijing Wang
Publikováno v:
American Journal of Gastroenterology. 115:2026-2035
INTRODUCTION Acute-on-chronic liver failure (ACLF) is defined by the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) consortium and the North American Consortium for the Study of End-Stage Liver Disease (NACSELD) as