Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gangarao Davuluri"'
Autor:
Elizabeth R. M. Zunica, Christopher L. Axelrod, Eunhan Cho, Guillaume Spielmann, Gangarao Davuluri, Stephanie J. Alexopoulos, Martina Beretta, Kyle L. Hoehn, Wagner S. Dantas, Krisztian Stadler, William T. King, Kathryn Pergola, Brian A. Irving, Ingeborg M. Langohr, Shengping Yang, Charles L. Hoppel, L. Anne Gilmore, John P. Kirwan
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Background Enhanced metabolic plasticity and diversification of energy production is a hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy efficacy, recurrence, and metastases. We have previously identif
Externí odkaz:
https://doaj.org/article/73646908050a40a890022b3871277182
Autor:
Shashi Shekhar Singh, Avinash Kumar, Nicole Welch, Jinendiran Sekar, Saurabh Mishra, Annette Bellar, Mahesha Gangadhariah, Amy Attaway, Hayder Al Khafaji, Xiaoqin Wu, Vai Pathak, Vandana Agrawal, Megan R. McMullen, Troy A. Hornberger, Laura E. Nagy, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 91-116 (2021)
Externí odkaz:
https://doaj.org/article/149adb9bba314f0284ac3b35b53225aa
Autor:
Avinash Kumar, Nicole Welch, Saurabh Mishra, Annette Bellar, Rafaella Nasciemento Silva, Ling Li, Shashi Shekhar Singh, Mary Sharkoff, Alexis Kerr, Aruna Kumar Chelluboyina, Jinendiran Sekar, Amy H. Attaway, Charles Hoppel, Belinda Willard, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including senescence induction. During dysregulated ammonia metabolism, which occurs in chronic diseases, skeletal muscle becomes a major organ for nonhepatocyte ammo
Externí odkaz:
https://doaj.org/article/0ebae34ec55e4a5d9fee0cbae28c8a7f
Autor:
Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp n/a-n/a (2020)
Abstract Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerab
Externí odkaz:
https://doaj.org/article/61fe5cb6b2dd4631b169f643148abc19
Autor:
Jenny G. Parvani, Gangarao Davuluri, Michael K. Wendt, Christine Espinosa, Maozhen Tian, David Danielpour, Khalid Sossey-Alaoui, William P. Schiemann
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 3, Pp 317-328 (2015)
Transforming growth factor–β (TGF-β) functions to suppress tumorigenesis in normal mammary tissues and early-stage breast cancers and, paradoxically, acts to promote the metastasis and chemoresistance in late-stage breast cancers, particularly tr
Externí odkaz:
https://doaj.org/article/fc71e4ecab9a41399bb0ea076e55c862
Autor:
Gangarao Davuluri, Katarzyna Augoff, William P Schiemann, Edward F Plow, Khalid Sossey-Alaoui
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110627 (2014)
The WAVE3 cytoskeletal protein promotes cancer invasion and metastasis. We have shown that the WAVE3-mediated activation of cancer cell invasion is due, in part, to its regulation of expression and activity of key metalloproteinases (MMPs), including
Externí odkaz:
https://doaj.org/article/c8729518957c4a64928cb890dde581b0
Autor:
Christoph Seiler, Gangarao Davuluri, Joshua Abrams, Fitzroy J Byfield, Paul A Janmey, Michael Pack
Publikováno v:
PLoS Biology, Vol 10, Iss 9, p e1001386 (2012)
The signals that initiate cell invasion are not well understood, but there is increasing evidence that extracellular physical signals play an important role. Here we show that epithelial cell invasion in the intestine of zebrafish meltdown (mlt) muta
Externí odkaz:
https://doaj.org/article/a095d5f72b0f457893d63f841e869257
Autor:
Gangarao Davuluri, Weilong Gong, Shamila Yusuff, Kristin Lorent, Manimegalai Muthumani, Amy C Dolan, Michael Pack
Publikováno v:
PLoS Genetics, Vol 4, Iss 10, p e1000240 (2008)
The recessive lethal mutation flotte lotte (flo) disrupts development of the zebrafish digestive system and other tissues. We show that flo encodes the ortholog of Mel-28/Elys, a highly conserved gene that has been shown to be required for nuclear in
Externí odkaz:
https://doaj.org/article/595b53caeb74487caf4f2ec9a39d0356
Autor:
Gangarao Davuluri, Maradumane L. Mohan, George R. Stark, Rebecca L. McCullough, Samjhana Thapaliya, Srinivasan Dasarathy, Laura E. Nagy, Megan R. McMullen, Sathyamangla V. Naga Prasad, Jinendiran Sekar, Mahesha Gangadhariah, Nicole Welch, McKenzie Stine, Sashi Kant, Avinash Kumar, Khaled Alsabbagh Alchirazi
Publikováno v:
Hepatology
BACKGROUND AND AIMS Despite the high clinical significance of sarcopenia in alcohol-associated cirrhosis, there are currently no effective therapies because the underlying mechanisms are poorly understood. We determined the mechanisms of ethanol-indu
Autor:
Megan R. McMullen, Mahesha Gangadhariah, Srinivasan Dasarathy, Troy A. Hornberger, Saurabh Mishra, Gangarao Davuluri, Hayder Al Khafaji, Avinash Kumar, Annette Bellar, Laura E. Nagy, Xiaoqin Wu, Amy Attaway, Nicole Welch, Vandana Agrawal, Shashi Shekhar Singh, Vai Pathak, Jinendiran Sekar
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 91-116 (2021)
BACKGROUND/AIMS: Signaling and metabolic perturbations contribute to dysregulated skeletal muscle protein homeostasis and secondary sarcopenia in response to a number of cellular stressors including ethanol exposure. Using an innovative multiomics-ba