Výsledky vyhledávání - "Gang-Jun Yuan"

Data from CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

Autor: Dan Xie, Fang-Jian Zhou, Tie-Bang Kang, Xin-Yuan Guan, Wei Chen, Hai-Liang Liu, Xiao-Han Jin, Jie-Wei Chen, Li-Juan Jiang, Jun Lu, Ri-Xin Chen, Mu-Yan Cai, Yong Feng, Ning-Fang Ma, Gang-Jun Yuan, Song Wu, Jun-Hang Luo, Jia-Xing Zhang, Xin Chen

Shortening of the 3′ untranslated regions (3′UTR) of mRNA is an important mechanism for oncogene activation. However, 3′UTR alteration events, their pathologic functions, and underlying mechanisms in human urothelial carcinoma of the bladder (U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f9e32d992ab68581454cf3db0ac66d2
https://doi.org/10.1158/0008-5472.c.6510432.v1

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Supplementary Data from CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

Supplementary Figure S1. Identification of 3'UTR shortening of RALA and RAC1 from UCB, colorectal carcinoma, hepatocellular carcinoma and non-small cell lung cancer samples. Supplementary Figure S2. RAC1 with short 3'UTR promotes tumorigenesis and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52aae70f232f3f3ff5cca38590d17955
https://doi.org/10.1158/0008-5472.22419636.v1

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Data from PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition

Autor: Dan Xie, Fang-Jian Zhou, Jun-Hang Luo, Zhuo-Wei Liu, Kang-Hua Xiao, Sheng-Jie Guo, Si-Liang Chen, Gang-Jun Yuan, Jie-Wei Chen, Lei Tan, Zi-Hao Feng, Yong-Hong Li, Wen-Su Wei, Ri-Xin Chen, Xin Chen

Purpose: Circular RNAs (circRNAs), a novel class of noncoding RNAs, have recently drawn lots of attention in the pathogenesis of human cancers. However, the role of circRNAs in cancer cells epithelial–mesenchymal transition (EMT) remains unclear. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cec5ede6704f3b40b6d5d9d02b5db4
https://doi.org/10.1158/1078-0432.c.6527492

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PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition

Autor: Fangjian Zhou, Gang Jun Yuan, Yong Hong Li, Zi Hao Feng, Ri Xin Chen, Kang Hua Xiao, Lei Tan, Wen Su Wei, Si Liang Chen, Jie Wei Chen, Jun Hang Luo, Xin Chen, Sheng Jie Guo, Zhuo Wei Liu, Dan Xie

Publikováno v: Clinical Cancer Research. 24:6319-6330

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7b8d54706d79f2788ba3448f7c9e62
https://doi.org/10.1158/1078-0432.ccr-18-1270

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CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

Autor: Gang Jun Yuan, Xiao Han Jin, Li Juan Jiang, Fangjian Zhou, Jie Wei Chen, Tiebang Kang, Jun Lu, Dan Xie, Wei Chen, Jia Xing Zhang, Jun Hang Luo, Xin Yuan Guan, Xin Chen, Mu Yan Cai, Ri Xin Chen, Yong Feng, Song Wu, Ning-Fang Ma, Hailiang Liu

Publikováno v: Cancer Research. 78:5848-5862

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::476f4a79bf93d984388354321bd5b571
https://doi.org/10.1158/0008-5472.can-18-0822

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Chromobox homolog 8 is a predictor of muscle invasive bladder cancer and promotes cell proliferation by repressing the p53 pathway

Autor: Gang Jun Yuan, Dan Xie, Ri Xin Chen, Xin Chen, Jun Lu, Wen Su Wei, Zi Hao Feng, Si Liang Chen, Fang Jian Zhou

Publikováno v: Cancer Science

Chromobox homolog 8 (CBX8), also known as human polycomb 8, is a repressor that maintains the transcriptionally repressive state in various cellular genes, and has been reported to promote tumorigenesis. In the present study, we examined CBX8 express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e545f73d1e6c261011349b5e4bf9934
http://europepmc.org/articles/PMC5665758

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TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation

Autor: Gang Jun Yuan, Xin Chen, Fangjian Zhou, Li Juan Jiang, Zhuo Wei Liu, Le Ye He, Yong Hong Li, Ning-Fang Ma, Dan Xie, Zhi Lin Zhang, Xiangdong Li, Xiao Dan Ma, Wen Su Wei, Li Yi Guo, Shi Wei, Ri Xin Chen, Ming Hui Deng, Jun Hang Luo

Publikováno v: Cancer letters. 435

Clinically, most of human urothelial carcinoma of the bladder (UCB)-related deaths result from tumor metastasis, but the underlying molecular mechanisms are largely unknown. Recently, a growing number of tripartite motif (TRIM) family members have be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11258860ff882774329162c8bc1c85fb
https://pubmed.ncbi.nlm.nih.gov/30075204

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CSTF2-Induced Shortening of the

Autor: Xin, Chen, Jia-Xing, Zhang, Jun-Hang, Luo, Song, Wu, Gang-Jun, Yuan, Ning-Fang, Ma, Yong, Feng, Mu-Yan, Cai, Ri-Xin, Chen, Jun, Lu, Li-Juan, Jiang, Jie-Wei, Chen, Xiao-Han, Jin, Hai-Liang, Liu, Wei, Chen, Xin-Yuan, Guan, Tie-Bang, Kang, Fang-Jian, Zhou, Dan, Xie

Publikováno v: Cancer research. 78(20)

Shortening of the 3' untranslated regions (3'UTR) of mRNA is an important mechanism for oncogene activation. However, 3'UTR alteration events, their pathologic functions, and underlying mechanisms in human urothelial carcinoma of the bladder (UCB) ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbe4f85a3123b758123f0622b3936a8d
https://pubmed.ncbi.nlm.nih.gov/30143523

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