Reply to: Accurate Determinants of Outcome in ALL.

Autor: Chang TC; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Chen W; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Qu C; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Cheng Z; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Elsayed A; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Pounds SB; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Shago M; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Rabin KR; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Raetz EA; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Devidas M; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Cheng C; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Angiolillo A; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Baviskar P; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Borowitz M; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Burke MJ; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Carroll A; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Carroll WL; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Chen IM; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Harvey R; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Heerema N; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Iacobucci I; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Wang JR; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Jeha S; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Larsen E; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Mattano L; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Maloney K; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Pui CH; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Ramirez NC; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Salzer W; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Willman C; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Winick N; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Wood B; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Hunger SP; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Wu G; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Mullighan CG; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA., Loh ML; Ti-Cheng Chang, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Wenan Chen, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Division of Computational Biology, Mayo Clinic, Rochester, MN; Chunxu Qu, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Zhongshan Cheng, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN; Abdelrahman Elsayed, PhD and Stanley B. Pounds, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Mary Shago, PhD, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Karen R. Rabin, MD, PhD, Department of Pediatrics, Baylor College of Medicine, Houston, TX; Elizabeth A. Raetz, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; Meenakshi Devidas, PhD, Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN; Cheng Cheng, PhD, Department of Biostatistics, St Jude Children's Research Hospital, Memphis, TN; Anne Angiolillo, MD, Children's National Medical Center, Washington, DC; Pradyuamma Baviskar, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Michael Borowitz, MD, Department of Pathology, Johns Hopkins University, Baltimore, MD; Michael J. Burke, MD, Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI; Andrew Carroll, PhD, Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; William L. Carroll, MD, Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Hospital, New York, NY; I-Ming Chen, DVM and Richard Harvey, PhD, Department of Pathology, University of New Mexico, Albuquerque, NM; Nyla Heerema, PhD, The Ohio State University, Columbus, OH; Ilaria Iacobucci, PhD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Jeremy R. Wang, PhD, Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Sima Jeha, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Eric Larsen, MD, Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, MD, HARP Pharma Consulting, Mystic, CT; Kelly Maloney, MD, Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO; Ching-Hon Pui, MD, Department of Oncology, St Jude Children's Research Hospital, Memphis, TN; Nilsa C. Ramirez, MD, Institute for Genomic Medicine and Biopathology Center, Nationwide Children's Hospital, Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH; Wanda Salzer, MD, Uniformed Services University, School of Medicine, Bethesda, MD; Cheryl Willman, MD, Department of Laboratory Medicine and Pathology and Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN; Naomi Winick, MD, Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Brent Wood, MD, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA; Stephen P. Hunger, MD, Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Gang Wu, PhD, Center for Applied Bioinformatics, St Jude Children's Research Hospital, Memphis, TN, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; Charles G. Mullighan, MBBS, MD, Department of Pathology, St Jude Children's Research Hospital, Memphis, TN; and Mignon L. Loh, MD, Department of Pediatrics and the Ben Towne Center for Childhood Cancer Research, Seattle Children's Hospital, University of Washington, Seattle, WA.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Dec 23, pp. JCO2402335. Date of Electronic Publication: 2024 Dec 23.