Supplementary figures 1-2 from Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

Autor: Alexander Drilon, Marc Ladanyi, Pratik Multani, Rupal Patel, Jennifer W. Oliver, Ge Wei, Shunqi Yan, Jason Harris, Gregory J. Riely, Eric Martin, Anni Schairer, Aleksandra Franovic, Leenus Martin, Takuo Hayashi, Roger S. Smith, James Joseph, Romel Somwar, Gang G. Li

Supplementary Figure 1. In vitro characterization of RET inhibitory activity of RXDX-105 in HBEC3KT-RET cells; Supplementary Figure 2. In vivo efficacy of RXDX-105 in a xenograft model of HBEC3KT-RET harboring CCDC6-RET fusion.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf2627da5d44cfbb7ffef3f298ea800
https://doi.org/10.1158/1078-0432.22462959

Supplementary figure legends from Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

Autor: Alexander Drilon, Marc Ladanyi, Pratik Multani, Rupal Patel, Jennifer W. Oliver, Ge Wei, Shunqi Yan, Jason Harris, Gregory J. Riely, Eric Martin, Anni Schairer, Aleksandra Franovic, Leenus Martin, Takuo Hayashi, Roger S. Smith, James Joseph, Romel Somwar, Gang G. Li

Supplementary figure legends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8744d89bf98cc5c97a904a370b94485d
https://doi.org/10.1158/1078-0432.22462962.v1

Antitumor Activity of RXDX-105 in Multiple Cancer Types with

Autor: Gang G, Li, Romel, Somwar, James, Joseph, Roger S, Smith, Takuo, Hayashi, Leenus, Martin, Aleksandra, Franovic, Anni, Schairer, Eric, Martin, Gregory J, Riely, Jason, Harris, Shunqi, Yan, Ge, Wei, Jennifer W, Oliver, Rupal, Patel, Pratik, Multani, Marc, Ladanyi, Alexander, Drilon

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 23(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91049061c6f5ea54258cab2e386e715f
https://pubmed.ncbi.nlm.nih.gov/28011461

Probing the effect of protein corona on SERS signals: insights from melamine detection in milk matrix.

Autor: Mi S; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Du Y; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Gao F; Center of Agro-product Safety and Quality, Ministry of Agriculture and Rural Affairs, Beijing, China., Yuan S; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Yu H; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Guo Y; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Cheng Y; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China., Li G; Inner Mongolia Agricultural and Livestock Product Quality and Safety Center, Hohhot, China., Yao W; State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, China. Electronic address: yaoweirongcn@jiangnan.edu.cn.

Publikováno v: Food chemistry [Food Chem] 2024 Nov 30; Vol. 459, pp. 140416. Date of Electronic Publication: 2024 Jul 14.

Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma.

Autor: Fernandez EG; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Mai WX; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Song K; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA., Bayley NA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Kim J; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA., Zhu H; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Pioso M; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Young P; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Andrasz CL; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Department of Human Genetics, University of California, Los Angeles, CA, 90095-7088, USA., Cadet D; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Liau LM; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Li G; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA., Yong WH; Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Rodriguez FJ; Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Dixon SJ; Department of Biology, Stanford University, Stanford, CA, 94305, USA., Souers AJ; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Li JJ; Department of Biostatistics, Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California, Los Angeles, CA, 90095-7088, USA.; Department of Computational Medicine, University of California, Los Angeles, CA, 90095-1766, USA.; Department of Statistics and Data Science, University of California, Los Angeles, CA, 90095-1554, USA., Graeber TG; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; UCLA Metabolomics Center, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Crump Institute for Molecular Imaging, University of California Los Angeles, Los Angeles, CA, 90095, USA., Cloughesy TF; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nathanson DA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA. dnathanson@mednet.ucla.edu.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA. dnathanson@mednet.ucla.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 21; Vol. 15 (1), pp. 10089. Date of Electronic Publication: 2024 Nov 21.